Time- and Race-Specific Haematological Reference Intervals for Healthy Volunteer Trials: A Retrospective Analysis of Pooled Data From Multiple Phase I Trials

Autor: Simon Coates, Duolao Wang, Tomasz Pierscionek, Sara Fernandes, Dilshat Djumanov, Ulrike Lorch, Jörg Täubel

Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)

Most UK hospitals, laboratories, and research institutions use uniform reference intervals (RI) that do not take into account known diurnal and racial variation in total white blood cells (WBC) count and its constituent parameters. These risks of exc

Externí odkaz: https://doaj.org/article/51cc5242870b46cda644af7673f77490

Association between C677T polymorphism of methylene tetrahydrofolate reductase and congenital heart disease: meta-analysis of 7697 cases and 13,125 controls

Autor: Jamie Bentham, Tomasz Pierscionek, Jeroen Breckpot, Klaartje van Engelen, Antoon F.M. Moorman, Kerry Setchfield, Marc Gewillig, Catherine Cosgrove, Faith Pangilinan, Shoumo Bhattacharya, G. Mark Lathrop, Koenraad Devriendt, James L. Mills, R Reid Prentice, Lawrence C. Brody, Frances A. Bu'Lock, Barbara J.M. Mulder, Danielle L. Brown, Martin Farrall, Mark W. Russell, Chris Thornborough, Javier Granados Riveron, Kenneth A. Pass, Gillian M. Blue, Alex V. Postma, A. H. Zwinderman, Judith A. Goodship, Darroch Hall, David S. Winlaw, John O'Sullivan, Chrysovalanto Mamasoula, Bernard Keavney, Charlotte M. Druschel, A Graham Stuart, Diana Zelenika, J. David Brook, Thahira Rahman, Heather J. Cordell, Anita Rauch, Ana Töpf, Huay Lin Tan, Julian Palomino Doza

Publikováno v: Circulation. Cardiovascular genetics, 6(4), 347-353. Lippincott Williams and Wilkins
Circulation: Cardiovascular Genetics; Vol 6
Circulation: Cardiovascular Genetics, 6(4), 347-353. Lippincott Williams and Wilkins
Mamasoula, C, Prentice, R R, Pierscionek, T, Pangilinan, F, Mills, J L, Druschel, C, Pass, K, Russell, M W, Hall, D, Töpf, A, Brown, D L, Zelenika, D, Bentham, J, Cosgrove, C, Bhattacharya, S, Riveron, J G, Setchfield, K, Brook, J D, Bu'Lock, F A, Thornborough, C, Rahman, T J, Doza, J P, Tan, H L, O'Sullivan, J, Stuart, A G, Blue, G, Winlaw, D, Postma, A V, Mulder, B J M, Zwinderman, A H, Van Engelen, K, Moorman, A F M, Rauch, A, Gewillig, M, Breckpot, J, Devriendt, K, Lathrop, G M, Farrall, M, Goodship, J A, Cordell, H J, Brody, L C & Keavney, B D 2013, ' Association between C677T polymorphism of methylene tetrahydrofolate reductase and congenital heart disease : Meta-analysis of 7697 cases and 13 125 controls ', Circulation: Cardiovascular Genetics, vol. 6, no. 4, pp. 347-353 . https://doi.org/10.1161/CIRCGENETICS.113.000191

Background— Association between the C677T polymorphism of the methylene tetrahydrofolate reductase ( MTHFR ) gene and congenital heart disease (CHD) is contentious. Methods and Results— We compared genotypes between CHD cases and controls and bet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142eb8f9ba01d94e70d20edc760cea3c
https://doi.org/10.5167/uzh-88189

High prevalence of HER-2/neu overexpression in female breast cancer among an Iraqi population exposed to depleted uranium

Autor: Asad A Al-Janabi, Akeel A. Yasseen, Tomasz Pierscionek, Esraa A. AL-Dujaily

Publikováno v: Journal of Carcinogenesis

Background This study aimed to estimate the rate of HER-2/neu (c-erbB2) immunohistochemical overexpression in different histological types of breast cancer found in the middle Euphrates region of Iraq, a region that was exposed to high levels of depl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e72f3d7205779da89d5a0044c513592
http://europepmc.org/articles/PMC2669727

Scotland increase minimum unit price of alcohol to increase to 50p

Autor: Tomasz Pierscionek

Publikováno v: BMJ. :e3600

A national bill to increase the minimum price of alcoholic beverages is being debated for the second time in the Scottish parliament. The Alcohol Minimum Pricing Bill, proposed by the Scottish National Party, would raise the minimum price of a unit o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da324620f80935f9e264f314f85ff259
https://doi.org/10.1136/sbmj.e3600

BMA calls on government to abandon price based competition in NHS

Autor: Tomasz Pierscionek

Publikováno v: BMJ. 342:d1142-d1142

The BMA’s General Practitioners Committee yesterday called on the government to abandon its proposed move to competition on the basis of price in the NHS in England, saying that it would affect the quality of care. The government introduced the con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c6a703bdfd75c6bcec894e2f7b20903
https://doi.org/10.1136/bmj.d1142