Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tomasz Pawiński"'
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 299 (2023)
Tacrolimus (TAC) is post-transplant pharmacotherapy’s most widely used immunosuppressant. In routine clinical practice, frequent uncomfortable venipuncture is necessary for whole-blood (WB) collection to check trough TAC levels. Volumetric absorpti
Externí odkaz:
https://doaj.org/article/5cf0cfc8b1794019b0a18aabb900ede2
Autor:
Magdalena Bodnar-Broniarczyk, Karola Warzyszyńska, Katarzyna Czerwińska, Dorota Marszałek, Natalia Dziewa, Maciej Kosieradzki, Tomasz Pawiński
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 632 (2022)
(1) Background: Only unbound tacrolimus particles are considered to be active and capable of crossing cellular membranes. Thus, the free-drug concentration might be better associated with clinical effects than the total drug concentration used for do
Externí odkaz:
https://doaj.org/article/54b146439f3b47e189daa207d8989922
Autor:
Magdalena Bodnar-Broniarczyk, Magdalena Durlik, Teresa Bączkowska, Katarzyna Czerwińska, Ryszard Marszałek, Tomasz Pawiński
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1576 (2021)
Tacrolimus (TAC) has a narrow therapeutic index and highly variable pharmacokinetic characteristics. Close monitoring of the TAC concentrations is required in order to avoid the risk of acute rejection or adverse drug reaction. The results in some st
Externí odkaz:
https://doaj.org/article/8085468a116040dabed66bdf13854e14
Publikováno v:
Therapeutic Drug Monitoring. 45:173-190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92b770aa609f8393e3c06d32f6a1ce0c
https://doi.org/10.1097/ftd.0000000000001041
https://doi.org/10.1097/ftd.0000000000001041
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 50:486-496
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ab5c65dbc75d973312aa7f6ffd35a13
https://doi.org/10.1111/1440-1681.13765
https://doi.org/10.1111/1440-1681.13765
Publikováno v:
Acta Poloniae Pharmaceutica - Drug Research. 79:799-807
This paper describes a simple, rapid and cost-effective HPLC-UV method for the determination of venlafaxine and its active metabolite O-desmethylvenlafaxine in human plasma. Sample preparation is based on a liquid-liquid extraction procedure with a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2dab65029ffc126cdea548e566a74a2
https://doi.org/10.32383/appdr/159659
https://doi.org/10.32383/appdr/159659
Autor:
Adam Stasiulewicz, Anna Lesniak, Magdalena Bujalska-Zadrożny, Tomasz Pawiński, Joanna I. Sulkowska
Publikováno v:
Journal of Chemical Information and Modeling. 63:1012-1027
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::401a8ecc5a0bf7ae4731dd8f910f5143
https://doi.org/10.1021/acs.jcim.2c01503
https://doi.org/10.1021/acs.jcim.2c01503
Publikováno v:
Prospects in Pharmaceutical Sciences. 18:40-49
Dehydrogenaza inozynomonofosforanowa (IMPDH) pełni kluczową rolę w syntezie i metabolizmie nukleotydów purynowych w szlaku de novo, szczególnie w komórkach limfocytów typu B i T. Wyróżniamy dwie izoformy tego enzymu (IMPDH I i IMPDH II) kodo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef5f121dbe601b4934da1833d2560072
https://doi.org/10.56782/pps.13
https://doi.org/10.56782/pps.13
Publikováno v:
Biomedical chromatography : BMC. 30(6)
Estimating the influence of interfering compounds present in the biological matrix on the determination of an analyte is one of the most important tasks during bioanalytical method development and validation. Interferences from endogenous components
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::994edddfaa541dd00ffa6e85d0832a5f
https://pubmed.ncbi.nlm.nih.gov/26458096
https://pubmed.ncbi.nlm.nih.gov/26458096
Publikováno v:
Acta poloniae pharmaceutica. 65(1)
Combination therapy with protease inhibitors (PIs) is used for the treatment of patients infected with the human immunodeficiency virus (HIV). To achieve optimal drug concentrations for viral suppression and avoidance of drug toxicity, therapeutic dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41823dfd9fee44d9f980e422b94b24db
https://pubmed.ncbi.nlm.nih.gov/18536180
https://pubmed.ncbi.nlm.nih.gov/18536180