Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tomasz Pawiński"'
Autor:
Arkadiusz Kocur, Agnieszka Czajkowska, Mateusz Moczulski, Bartłomiej Kot, Jacek Rubik, Tomasz Pawiński
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8760 (2024)
Ganciclovir (GCV) and its prodrug valganciclovir (VGCV) are antiviral medications primarily used to treat infections caused by cytomegalovirus (CMV), particularly in immunocompromised individuals such as solid organ transplant (SOT) recipients. Thera
Externí odkaz:
https://doaj.org/article/3f8f0b54e5d544e9bc9315cf5d509795
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 299 (2023)
Tacrolimus (TAC) is post-transplant pharmacotherapy’s most widely used immunosuppressant. In routine clinical practice, frequent uncomfortable venipuncture is necessary for whole-blood (WB) collection to check trough TAC levels. Volumetric absorpti
Externí odkaz:
https://doaj.org/article/5cf0cfc8b1794019b0a18aabb900ede2
Autor:
Arkadiusz Kocur, Tomasz Pawiński
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 681 (2022)
Miniaturisation and simplification are novel approaches in clinical bioanalysis, especially in therapeutic drug monitoring (TDM). These contemporary trends are related to the sampling, pre-treatment, and analysis of biological fluids. Currently, drie
Externí odkaz:
https://doaj.org/article/580a9b692f2b495984e8c5d8bb57ac92
Autor:
Magdalena Bodnar-Broniarczyk, Karola Warzyszyńska, Katarzyna Czerwińska, Dorota Marszałek, Natalia Dziewa, Maciej Kosieradzki, Tomasz Pawiński
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 632 (2022)
(1) Background: Only unbound tacrolimus particles are considered to be active and capable of crossing cellular membranes. Thus, the free-drug concentration might be better associated with clinical effects than the total drug concentration used for do
Externí odkaz:
https://doaj.org/article/54b146439f3b47e189daa207d8989922
Autor:
Magdalena Bodnar-Broniarczyk, Magdalena Durlik, Teresa Bączkowska, Katarzyna Czerwińska, Ryszard Marszałek, Tomasz Pawiński
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1576 (2021)
Tacrolimus (TAC) has a narrow therapeutic index and highly variable pharmacokinetic characteristics. Close monitoring of the TAC concentrations is required in order to avoid the risk of acute rejection or adverse drug reaction. The results in some st
Externí odkaz:
https://doaj.org/article/8085468a116040dabed66bdf13854e14
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8, p 2778 (2020)
The endocannabinoid system (ECS) is one of the most crucial systems in the human organism, exhibiting multi-purpose regulatory character. It is engaged in a vast array of physiological processes, including nociception, mood regulation, cognitive func
Externí odkaz:
https://doaj.org/article/6afac12a14ec41bd8ecbbbcfe248f9cf
Publikováno v:
Therapeutic Drug Monitoring. 45:173-190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92b770aa609f8393e3c06d32f6a1ce0c
https://doi.org/10.1097/ftd.0000000000001041
https://doi.org/10.1097/ftd.0000000000001041
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 50:486-496
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ab5c65dbc75d973312aa7f6ffd35a13
https://doi.org/10.1111/1440-1681.13765
https://doi.org/10.1111/1440-1681.13765
Publikováno v:
Acta Poloniae Pharmaceutica - Drug Research. 79:799-807
This paper describes a simple, rapid and cost-effective HPLC-UV method for the determination of venlafaxine and its active metabolite O-desmethylvenlafaxine in human plasma. Sample preparation is based on a liquid-liquid extraction procedure with a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2dab65029ffc126cdea548e566a74a2
https://doi.org/10.32383/appdr/159659
https://doi.org/10.32383/appdr/159659
Autor:
Adam Stasiulewicz, Anna Lesniak, Magdalena Bujalska-Zadrożny, Tomasz Pawiński, Joanna I. Sulkowska
Publikováno v:
Journal of Chemical Information and Modeling. 63:1012-1027
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::401a8ecc5a0bf7ae4731dd8f910f5143
https://doi.org/10.1021/acs.jcim.2c01503
https://doi.org/10.1021/acs.jcim.2c01503