Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Tomasz M, Kulinski"'
Autor:
Daniel Andergassen, Markus Muckenhuber, Philipp C Bammer, Tomasz M Kulinski, Hans-Christian Theussl, Takahiko Shimizu, Josef M Penninger, Florian M Pauler, Quanah J Hudson
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1009151 (2020)
[This corrects the article DOI: 10.1371/journal.pgen.1008268.].
Externí odkaz:
https://doaj.org/article/e3b0679cd3ec4221a2c5e55dd74ef5f1
Dedicated surveillance mechanism controls G-quadruplex forming non-coding RNAs in human mitochondria
Autor:
Zbigniew Pietras, Magdalena A. Wojcik, Lukasz S. Borowski, Maciej Szewczyk, Tomasz M. Kulinski, Dominik Cysewski, Piotr P. Stepien, Andrzej Dziembowski, Roman J. Szczesny
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
G-rich RNAs encoded in mitochondrial DNA are prone to form four-stranded structures called G-quadruplexes (G4s). Here the authors show using in vitro and in vivo approaches that GRSF1 promotes melting of G4 RNA structures in mtRNAs, thus leading to t
Externí odkaz:
https://doaj.org/article/ecae75cc636546cf9e7e85d311c81677
Autor:
Daniel Andergassen, Markus Muckenhuber, Philipp C Bammer, Tomasz M Kulinski, Hans-Christian Theussl, Takahiko Shimizu, Josef M Penninger, Florian M Pauler, Quanah J Hudson
Publikováno v:
PLoS Genetics, Vol 15, Iss 7, p e1008268 (2019)
Long non-coding (lnc) RNAs are numerous and found throughout the mammalian genome, and many are thought to be involved in the regulation of gene expression. However, the majority remain relatively uncharacterised and of uncertain function making the
Externí odkaz:
https://doaj.org/article/7321d8c7237440ca83e2b086f04dd999
Autor:
Zbigniew Pietras, Magdalena A. Wojcik, Lukasz S. Borowski, Maciej Szewczyk, Tomasz M. Kulinski, Dominik Cysewski, Piotr P. Stepien, Andrzej Dziembowski, Roman J. Szczesny
Publikováno v:
Molecular & Cellular Oncology, Vol 5, Iss 6 (2018)
Transcription of the human mitochondrial genome produces a vast amount of non-coding antisense RNAs. These RNA species can form G-quadraplexes (G4), which affect their decay. We found that the mitochondrial degradosome, a complex of RNA helicase SUPV
Externí odkaz:
https://doaj.org/article/68a4455d506c46f09067bb904eb47092
Autor:
Roman J Szczesny, Katarzyna Kowalska, Kamila Klosowska-Kosicka, Aleksander Chlebowski, Ewelina P Owczarek, Zbigniew Warkocki, Tomasz M Kulinski, Dorota Adamska, Kamila Affek, Agata Jedroszkowiak, Anna V Kotrys, Rafal Tomecki, Pawel S Krawczyk, Lukasz S Borowski, Andrzej Dziembowski
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194887 (2018)
Deciphering a function of a given protein requires investigating various biological aspects. Usually, the protein of interest is expressed with a fusion tag that aids or allows subsequent analyses. Additionally, downregulation or inactivation of the
Externí odkaz:
https://doaj.org/article/5a180779111c48eab736888d65918961
Autor:
Daniel Andergassen, Christoph P Dotter, Daniel Wenzel, Verena Sigl, Philipp C Bammer, Markus Muckenhuber, Daniela Mayer, Tomasz M Kulinski, Hans-Christian Theussl, Josef M Penninger, Christoph Bock, Denise P Barlow, Florian M Pauler, Quanah J Hudson
Publikováno v:
eLife, Vol 6 (2017)
To determine the dynamics of allelic-specific expression during mouse development, we analyzed RNA-seq data from 23 F1 tissues from different developmental stages, including 19 female tissues allowing X chromosome inactivation (XCI) escapers to also
Externí odkaz:
https://doaj.org/article/56a76cb9f51a468ea09e84df56a0f1ab
Autor:
Tomasz M. Kulinski, Jacek Milek, Michał Wasilewski, Bozena Kuzniewska, Ewelina Knapska, Agnieszka Chacinska, Maciej Winiarski, Michal Dadlez, Paulina Sakowska, Magdalena Dziembowska, Paweł Kozielewicz, And Andrzej Dziembowski, Dominik Cysewski
Publikováno v:
EMBO Reports
Synapses are the regions of the neuron that enable the transmission and propagation of action potentials on the cost of high energy consumption and elevated demand for mitochondrial ATP production. The rapid changes in local energetic requirements at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfbd55251fa605129d3a51b0133f0960
http://europepmc.org/articles/PMC7403725
http://europepmc.org/articles/PMC7403725
Dedicated surveillance mechanism controls G-quadruplex forming non-coding RNAs in human mitochondria
Autor:
Tomasz M. Kulinski, Piotr P. Stepien, Zbigniew Pietras, Magdalena A. Wojcik, Dominik Cysewski, Andrzej Dziembowski, Lukasz S. Borowski, Maciej Szewczyk, Roman J. Szczesny
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications
Nature Communications
The GC skew in vertebrate mitochondrial genomes results in synthesis of RNAs that are prone to form G-quadruplexes (G4s). Such RNAs, although mostly non-coding, are transcribed at high rates and are degraded by an unknown mechanism. Here we describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aacf3071a377ce02ed789a616e29c7f
http://link.springer.com/article/10.1038/s41467-018-05007-9
http://link.springer.com/article/10.1038/s41467-018-05007-9
Autor:
Jacek Milek, Paulina Sakowska, Magdalena Dziembowska, Michal Dadlez, Dominik Cysewski, Agnieszka Chacinska, Andrzej Dziembowski, Tomasz M. Kulinski, Paweł Kozielewicz, Michał Wasilewski, Bozena Kuzniewska
SummarySynapses are the regions of the neuron that enable the transmission and propagation of action potentials on the cost of high energy consumption and elevated demand for mitochondrial ATP production. The rapid changes in local energetic requirem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee83985482edb3fd2de971378487a169
https://doi.org/10.1101/789164
https://doi.org/10.1101/789164
Autor:
Zbigniew Pietras, Rafal Tomecki, Andrzej Dziembowski, Aleksander Chlebowski, Dominik Cysewski, Tomasz M. Kulinski, Katarzyna Kowalska, Katarzyna Kalisiak
Publikováno v:
Nucleic Acids Research
The exosome complex is a major eukaryotic exoribonuclease that requires the SKI complex for its activity in the cytoplasm. In yeast, the Ski7 protein links both complexes, whereas a functional equivalent of the Ski7 has remained unknown in the human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6dafe1a7e18f67436b6c63aad4b442
http://europepmc.org/articles/PMC5389692
http://europepmc.org/articles/PMC5389692