Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tomasz Gogiel"'
Autor:
Marta Bruczko, Krzysztof Sobolewski, Lech Romanowicz, Radosław Kowalewski, Małgorzata Wolańska, Tomasz Gogiel
Publikováno v:
International Journal of Experimental Pathology. 100:94-101
Vascular surgical interventions are often burdened with late complications, including thrombosis or restenosis. The latter is generally caused by neointimal hyperplasia. Although extracellular matrix (ECM) remodelling is an important part of neointim
Autor:
Lech Romanowicz, Tomasz Gogiel, Tomasz Guszczyn, Janusz Popko, Małgorzata Wolańska, Justyna Bączyk, Marta Bruczko
Publikováno v:
International Journal of Peptide Research and Therapeutics. 26:271-280
The progressive damage of human articular cartilage is associated with loss of integrity of its extracellular matrix components. Their metabolism is under the control of cytokines produced locally. It is known that peptide growth factors stimulate ch
Autor:
Tomasz Gogiel, Lech Romanowicz, Justyna Bączyk, Wiesława Roszkowska-Jakimiec, Zofia Galewska, Krzysztof Sobolewski, Marta Bruczko
Publikováno v:
European Journal of Obstetrics & Gynecology and Reproductive Biology. 231:48-53
Objectives Preeclampsia is the most common disorder associated with pregnancy. Our earlier findings revealed a substantial increase in the amount of matrix metalloproteinase-26 (matrilysin 2; MMP-26) in preeclamptic umbilical cord blood. The role of
Autor:
Krzysztof Sobolewski, Piotr Kinalski, Małgorzata Wolańska, Tomasz Gogiel, Lech Romanowicz, Zofia Galewska
Publikováno v:
Acta Biochimica Polonica. 64:507-512
The extracellular matrix components show specific distribution patterns within various structures of the umbilical cord, among which Wharton's jelly is especially collagen-rich tissue. Cathepsin L is a potent cysteine protease engaged in degradation
Publikováno v:
Toxicology Mechanisms and Methods
Preeclampsia is accompanied by an extensive remodeling of the extracellular matrix of umbilical cord. It is associated with an increase in collagen content in the umbilical cord artery. Furthermore, preeclampsia distinctly reduces proteolytic and gel
Publikováno v:
Pathobiology. 73:310-316
Background: Our previous studies demonstrated that preeclampsia is accompanied by significant alterations in the amounts of peptide growth factors in the umbilical cord serum. Some of these factors (especially IGF-1) are known as regulators of collag
Autor:
Małgorzata Wolańska, Stefan Jaworski, Tomasz Gogiel, Edward Bańkowski, Lech Romanowicz, Zofia Galewska
Publikováno v:
Clinica Chimica Acta. 351:177-184
Background Preeclampsia is accompanied by an increase of collagen contents in the umbilical cord (UC) arteries and in Wharton's jelly. Cathepsin D is one of the enzymes which participates in collagen degradation and activates precursor forms of colla
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 35:1461-1469
Wharton’s jelly (WJ) is a myxomatous substance surrounding the blood vessels of the umbilical cord. Proteoglycans (PGs) of Wharton’s jelly have not been studied to date therefore it was decided to explore proteoglycan composition of this tissue.
Autor:
Tomasz Gogiel, Maciej Kinalski, Małgorzata Wolańska, Krzysztof Sobolewski, Zofia Galewska, Lech Romanowicz
Publikováno v:
European journal of obstetrics, gynecology, and reproductive biology. 185
Objective Cathepsin B is a major cysteine protease involved in the degradation of extracellular matrix proteins, as well as in the activation of precursor forms of other proteases and in release of matrix-bound growth factors. We assessed the express
Publikováno v:
Pathobiology. 69:212-218
Objective: The role of proteoglycans (PGs) of the umbilical cord arteries (UCAs) in the pathomechanism of pre-eclampsia is not known. Therefore we decided to compare the PGs of normal (control) UCAs and those of newborns delivered by mothers with pre