Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tomasz Domoradzki"'
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2799 (2022)
Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor in adults with a poor prognosis. Despite significant progress in drug development, the blood–brain barrier (BBB) continues to limit the use of novel chemotherapeutics. T
Externí odkaz:
https://doaj.org/article/52984fec04664b2380270c0d309d5d14
Autor:
Beata Pająk, Ewelina Siwiak-Niedbalska, Anna Jaśkiewicz, Maja Sołtyka, Rafał Zieliński, Tomasz Domoradzki, Izabela Fokt, Stanisław Skóra, Waldemar Priebe
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1749 (2021)
Over the last decade, we have seen tremendous progress in research on 2-deoxy-D-glucose (2-DG) and its analogs. Clinical trials of 2-DG have demonstrated the challenges of using 2-DG as a monotherapy, due to its poor drug-like characteristics, leadin
Externí odkaz:
https://doaj.org/article/0059a481e2a447b882323f913e1c01d8
Autor:
Maciej Błaszczyk, Małgorzata Gajewska, Marta Dymowska, Alicja Majewska, Tomasz Domoradzki, Adam Prostek, Rafał Pingwara, Magdalena Hulanicka, Katarzyna Grzelkowska-Kowalczyk
Publikováno v:
Histochemistry and cell biology. 157(5)
Interleukin (IL)-6, a known proinflammatory cytokine, is released in both visceral adipose tissue and contracting skeletal muscle. In this study, we used microRNA profiling as a screening method to identify miRNA species modified by IL-6 treatment in
Autor:
Ewelina Siwiak-Niedbalska, Waldemar Priebe, Izabela Fokt, Rafal Zielinski, Stanislaw Skora, Tomasz Domoradzki, Anna Jaśkiewicz, Beata Pająk, Maja Sołtyka
Publikováno v:
Biomedicines
Biomedicines, Vol 9, Iss 1749, p 1749 (2021)
Biomedicines; Volume 9; Issue 12; Pages: 1749
Biomedicines, Vol 9, Iss 1749, p 1749 (2021)
Biomedicines; Volume 9; Issue 12; Pages: 1749
Over the last decade, we have seen tremendous progress in research on 2-deoxy-D-glucose (2-DG) and its analogs. Clinical trials of 2-DG have demonstrated the challenges of using 2-DG as a monotherapy, due to its poor drug-like characteristics, leadin
Publikováno v:
Journal of applied genetics. 63(2)
Our concerns have been raised about whether prolonged exposure to ammunition-related chemicals could correlate with genomic instability predisposing to lung carcinogenesis. The group of professional soldiers engaged in routine ammunition analysis and
Autor:
Tomasz Domoradzki, Marta Milewska, Małgorzata Gajewska, Maciej Błaszczyk, Alicja Majewska, Katarzyna Grzelkowska-Kowalczyk, Magdalena Hulanicka
Publikováno v:
Cell and tissue research. 380(1)
Interleukin (IL)-6 is a proinflammatory cytokine released in injured and contracting skeletal muscles. In this study, we examined cellular expression of proteins associated with cytoskeleton organization and cell migration, chosen on the basis of mic
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8261, p 8261 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Muscle cachexia is one of the most critical unmet medical needs. Identifying the molecular background of cancer-induced muscle loss revealed a promising possibility of new therapeutic targets and new drug development. In this review, we will define t
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1889
Microarray-based transcriptomic profiling enables simultaneous measurement of expression of multiple genes from one biological sample. Here we describe a detailed protocol, which serves to examine global gene expression using whole genome oligonucleo
Publikováno v:
Methods in Molecular Biology ISBN: 9781493988969
Microarray-based transcriptomic profiling enables simultaneous measurement of expression of multiple genes from one biological sample. Here we describe a detailed protocol, which serves to examine global gene expression using whole genome oligonucleo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5a841dc3ab017d1b97427219aa5d123
https://doi.org/10.1007/978-1-4939-8897-6_9
https://doi.org/10.1007/978-1-4939-8897-6_9
Autor:
Tomasz Domoradzki, Marta Milewska, Magdalena Hulanicka, Małgorzata Gajewska, Katarzyna Grzelkowska-Kowalczyk, Alicja Majewska, Anna Ciecierska, Maciej Błaszczyk
Publikováno v:
Journal of cellular physiology. 234(11)
Interleukin (IL)-8 is released both in visceral adipose tissue and in contracting skeletal muscles. In this study, we examined cellular pathways associated with muscle hypertrophy, chosen on the basis of microRNA profiling, in differentiating rat pri