Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tomasz Budlewski"'
Autor:
Grzegorz Dudek, Sebastian Sakowski, Olga Brzezińska, Joanna Sarnik, Tomasz Budlewski, Grzegorz Dragan, Marta Poplawska, Tomasz Poplawski, Michał Bijak, Joanna Makowska
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0300717 (2024)
Machine learning (ML) algorithms can handle complex genomic data and identify predictive patterns that may not be apparent through traditional statistical methods. They become popular tools for medical applications including prediction, diagnosis or
Externí odkaz:
https://doaj.org/article/cacca4404d51460ea692419b62c432a3
Autor:
Konrad Walczak, Robert Stawski, Ewelina Perdas, Olga Brzezinska, Piotr Kosielski, Szymon Galczynski, Tomasz Budlewski, Gianluca Padula, Dariusz Nowak
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract It is believed that neutrophils extracellular traps (NETs) formation is responsible for the increase in cf DNA after exercise. Since T1DM is accompanied by enhanced NETs generation, we compared exercise-induced increase in cf DNA in 14 men w
Externí odkaz:
https://doaj.org/article/d06f130f80974e44958c3a6388e25aed
Autor:
Robert Stawski, Konrad Walczak, Ewelina Perdas, Anna Prymont-Przymińska, Anna Zwolińska, Piotr Kosielski, Tomasz Budlewski, Gianluca Padula, Hanna Jerczynska, Dariusz Nowak
Publikováno v:
Biology, Vol 10, Iss 3, p 181 (2021)
Numerous studies have shown that cf nDNA significantly rises in stress caused by exercise. However, during nuclear decondensation, released DNA is followed by histones. Histones are also a common disease marker. After PAD4 mediated hypercitrullinatio
Externí odkaz:
https://doaj.org/article/020390f7415747b7bfafda21ccbfae30
Autor:
Robert Stawski, Konrad Walczak, Piotr Kosielski, Pawel Meissner, Tomasz Budlewski, Gianluca Padula, Dariusz Nowak
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0178216 (2017)
Acute single strenuous exercise increases circulating cell free DNA (cf DNA). We tested whether three repeated bouts of exhaustive exercise induced the cf DNA response without development of tolerance in healthy men.Eleven average-trained men (age 34
Externí odkaz:
https://doaj.org/article/ed1585a3b10c4bc28b93816a92f6dd2e
Autor:
Grzegorz Galita, Joanna Sarnik, Gabriela Zajac, Olga Brzezinska, Tomasz Budlewski, Marta Poplawska, Karolina Przybyłowska-Sygut, Makowska Joanna, Tomasz Poplawski
Publikováno v:
Archives of Medical Science.
IntroductionRA is a common autoimmune heterogeneous joint disease of still unknown etiology. One of the characteristic features of RA is oxidative stress, most probably induced and stimulated by inappropriate B and T-cell activity. We have hypothesiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccb36d25edf3b384170a837b5de0d648
https://doi.org/10.5114/aoms/163133
https://doi.org/10.5114/aoms/163133
Autor:
Tomasz Budlewski, Joanna Sarnik, Grzegorz Galita, Grzegorz Dragan, Olga Brzezińska, Marta Popławska, Tomasz Popławski, Joanna Makowska
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7586
Single nucleotide polymorphisms in non-HLA genes are involved in the development of rheumatoid arthritis (RA). SNPS in genes: PADI4 (rs2240340), STAT4 (rs7574865), CD40 (rs4810485), PTPN22 (rs2476601), and TRAF1 (rs3761847) have been described as ris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ad02d51319f35d85a6d09a16c11b1f
Autor:
Robert Stawski, Tomasz Budlewski, Dariusz Nowak, Gianluca Padula, Szymon Gałczyński, Konrad Walczak, Piotr Kosielski, Olga Brzezińska, Ewelina Perdas
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
It is believed that neutrophils extracellular traps (NETs) formation is responsible for the increase in cf DNA after exercise. Since T1DM is accompanied by enhanced NETs generation, we compared exercise-induced increase in cf DNA in 14 men with T1DM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451d3ee0a6fac203ddd56041b957aa82
https://doi.org/10.1038/s41598-021-84201-0
https://doi.org/10.1038/s41598-021-84201-0
Autor:
Ewelina Perdas, Konrad Walczak, Piotr Kosielski, Tomasz Budlewski, Pawel Meissner, Dariusz Nowak, Agata Sarniak, Robert Stawski, Gianluca Padula, Anna Wlodarczyk
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04346e06606e3c06ebc705b75bb4289
https://doi.org/10.1038/s41598-020-68815-4
https://doi.org/10.1038/s41598-020-68815-4
Autor:
Tomasz Budlewski, Piotr Kosielski, Gianluca Padula, Pawel Meissner, Konrad Walczak, Anna Wlodarczyk, Agata Sarniak, Robert Stawski, Dariusz Nowak, Ewelina Perdas
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Objective Strenuous exercise increases circulating cell free DNA (cf DNA) and stimulates blood phagocytes to generate more reactive oxygen species (ROS) which may induce DNA strand breaks. We tested whether: (A) elevated cf DNA in response to three r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52691f8b60f074ca0eaa7ca46a309a3e
http://europepmc.org/articles/PMC6828751
http://europepmc.org/articles/PMC6828751
Autor:
Tomasz Budlewski, Konrad Walczak, Anna Zwolinska, Ewelina Perdas, Hanna Jerczynska, Dariusz Nowak, Anna Prymont-Przyminska, Piotr Kosielski, Robert Stawski, Gianluca Padula
Publikováno v:
Biology
Volume 10
Issue 3
Biology, Vol 10, Iss 181, p 181 (2021)
Volume 10
Issue 3
Biology, Vol 10, Iss 181, p 181 (2021)
Simple Summary Histones are also a common disease marker. After PAD4 mediated hypercitrullination extracellular H3Cit exhibits high toxicity contributing to tissue damage which, in cases of systemic inflammation, may lead to multiorgan failure and fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75254c9a4ec9c5fcd3bbf9a88908ef8f
https://doi.org/10.3390/biology10030181
https://doi.org/10.3390/biology10030181