Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Tomasz Brudek"'
Autor:
Jonas Folke, Marie Skougaard, Trine-Line Korsholm, Anne-Line Strange Laursen, Lisette Salvesen, Anne-Mette Hejl, Sara Bech, Annemette Løkkegaard, Tomasz Brudek, Sisse Bolm Ditlev, Susana Aznar
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-6 (2024)
Abstract This study investigates the presence of antinuclear antibodies (ANA) in three primary synucleinopathies – Parkinson’s disease (PD), multiple system atrophy (MSA), and dementia with Lewy bodies (DLB), compared to healthy controls. Autoinf
Externí odkaz:
https://doaj.org/article/42b448ee7219460495a8218d0bfd77d1
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
BackgroundAlcohol use disorder (AUD) is a major problem of our society and is often characterized and worsened by relapse. Prolonged alcohol exposure leads to numerous biochemical alterations that, upon cessation of alcohol intake, cause an array of
Externí odkaz:
https://doaj.org/article/5ccb12d54ea24bc6a28d887c49ec8b02
Autor:
Rasmus Rydbirk, Jonas Folke, Florence Busato, Elodie Roché, Alisha Shahzad Chauhan, Annemette Løkkegaard, Anne-Mette Hejl, Matthias Bode, Morten Blaabjerg, Mette Møller, Erik Hvid Danielsen, Tomasz Brudek, Bente Pakkenberg, Jorg Tost, Susana Aznar
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-14 (2020)
Abstract Multiple system atrophy (MSA) is a rare disease with a fatal outcome. To date, little is known about the molecular processes underlying disease development. Its clinical overlap with related neurodegenerative movement disorders underlines th
Externí odkaz:
https://doaj.org/article/b14bb7e1bdfb44779cb1ebeea84015cd
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 168 (2022)
Alpha-synucleinopathies include Parkinson’s disease, dementia with Lewy bodies, pure autonomic failure and multiple system atrophy. These are all progressive neurodegenerative diseases that are characterized by pathological misfolding and accumulat
Externí odkaz:
https://doaj.org/article/b974646d6bcb42389313e47f045edc8d
Autor:
Rasmus Rydbirk, Betina Elfving, Mille Dahl Andersen, Mia Aggergaard Langbøl, Jonas Folke, Kristian Winge, Bente Pakkenberg, Tomasz Brudek, Susana Aznar
Publikováno v:
Neurobiology of Disease, Vol 106, Iss , Pp 269-278 (2017)
Parkinson's Disease (PD) and Multiple System Atrophy (MSA) are neurodegenerative diseases characterized neuropathologically by alpha-synuclein accumulation in brain cells. This accumulation is hypothesized to contribute to constitutive neuroinflammat
Externí odkaz:
https://doaj.org/article/e72e45ce5e7d48bb968e685d05b015d5
Autor:
Tomasz Brudek, Kristian Winge, Jonas Folke, Søren Christensen, Karina Fog, Bente Pakkenberg, Lars Østergaard Pedersen
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-16 (2017)
Abstract Background Parkinson’s’ disease (PD) and Multiple System Atrophy (MSA) are progressive brain disorders characterized by intracellular accumulations of α-synuclein and nerve cell loss in specific brain areas. This loss causes problems wi
Externí odkaz:
https://doaj.org/article/39591607b2e94ca28088cbc05061b783
Autor:
Jonas Folke, Rasmus Rydbirk, Annemette Løkkegaard, Lisette Salvesen, Anne-Mette Hejl, Charlotte Starhof, Sára Bech, Kristian Winge, Søren Christensen, Lars Østergaard Pedersen, Susana Aznar, Bente Pakkenberg, Tomasz Brudek
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Aggregation of alpha-synuclein (α-syn) is considered to be the major pathological hallmark and driving force of Multiple System Atrophy (MSA) and Parkinson's disease (PD). Immune dysfunctions have been associated with both MSA and PD and recently we
Externí odkaz:
https://doaj.org/article/d8a97787e33849beb9489320df1be604
Autor:
Lisette Salvesen, Birgitte H. Ullerup, Fatma B. Sunay, Tomasz Brudek, Annemette Løkkegaard, Tina K. Agander, Kristian Winge, Bente Pakkenberg
Publikováno v:
Neurobiology of Disease, Vol 74, Iss , Pp 104-113 (2015)
Total numbers of neurons, oligodendrocytes, astrocytes, and microglia in the basal ganglia and red nucleus were estimated in brains from 11 patients with multiple system atrophy (MSA) and 11 age- and gender-matched control subjects with unbiased ster
Externí odkaz:
https://doaj.org/article/37314f73bf2c4eb0b242811a279f2319
Autor:
Nadja Bredo Rasmussen, Mikkel Vestergaard Olesen, Tomasz Brudek, Per Plenge, Anders Bue Klein, Jenny E. Westin, Karina Fog, Gitta Wörtwein, Susana Aznar
Publikováno v:
Parkinson's Disease, Vol 2016 (2016)
The 5-HT2A receptor is highly involved in aspects of cognition and executive function and seen to be affected in neurodegenerative diseases like Alzheimer’s disease and related to the disease pathology. Even though Parkinson’s disease (PD) is pri
Externí odkaz:
https://doaj.org/article/cb0b696cf31340e59888b6fb784b77dd
Autor:
Bjørn A Nexø, Tove Christensen, Jette Frederiksen, Anné Møller-Larsen, Annette B Oturai, Palle Villesen, Bettina Hansen, Kari K Nissen, Magdalena J Laska, Trine S Petersen, Sandra Bonnesen, Anne Hedemand, Tingting Wu, Xinjie Wang, Xiuqing Zhang, Tomasz Brudek, Romana Maric, Helle B Søndergaard, Finn Sellebjerg, Klaus Brusgaard, Anders L Kjeldbjerg, Henrik B Rasmussen, Anders L Nielsen, Mette Nyegaard, Thor Petersen, Anders D Børglum, Finn S Pedersen
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16652 (2011)
We have investigated the role of human endogenous retroviruses in multiple sclerosis by analyzing the DNA of patients and controls in 4 cohorts for associations between multiple sclerosis and polymorphisms near viral restriction genes or near endogen
Externí odkaz:
https://doaj.org/article/ac1043867bf5448089991b19aab17907