Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tomasz Anchim"'
Publikováno v:
Folia Histochemica et Cytobiologica, Vol 42, Iss 4, Pp 221-227 (2005)
Doxorubicin (Adriamycin) is the most active drug in the treatment of breast cancer. The aim of this study was to investigate the interaction of doxorubicin and retinoids in the inhibition of proliferation of hormone sensitive (ER+) human breast cance
Externí odkaz:
https://doaj.org/article/91db1332829d465abddea681dc155c36
Publikováno v:
Biological and Pharmaceutical Bulletin. 28:1004-1009
A number of novel 2-chloroethylnitrosourea derivatives of Hoechst 33258 were synthesized and examined for cytotoxicity in breast cancer cell cultures and for inhibition of topoisomerases I and II. Evaluation of the cytotoxicity of these compounds emp
Publikováno v:
ResearcherID
Retinoic acid and transforming growth factor-beta (TGF-beta) affect differentiation, proliferation and carcinogenesis of epithelial cells. The effect of both compounds on the proliferation of cells of the hormone sensitive human breast cancer cell li
Publikováno v:
Il Farmaco. 59:211-214
New carbocyclic potential minor groove binders were synthesised, using 3-nitrobenzoyl chloride and aliphatic α,ω-diamines with three, four and five methylene fragments. The half structures, compounds IV–VI can be compared to bis-amidines, compoun
Autor:
Tomasz Anchim, Halina Porowska, Andrzej Gindzieński, Slawomir Wolczynski, Paszkiewicz-Gadek A
Publikováno v:
Gynecological Endocrinology. 17:37-44
Polymorphic epithelial mucin MUC1 is expressed by most epithelial cancers, although free natural MUC1 antibodies are present in the circulation of healthy subjects as well as in that of cancer patients. The role of MUC1 mucin molecules in cancer cell
Autor:
Tomasz Anchim, Slawomir Wolczynski, Jerzy Pałka, Ryszard Lesniewicz, Arkadiusz Surażyński, Anna Galicka
Publikováno v:
European Journal of Biochemistry. 268:2172-2178
We have studied the structure and metabolism of type I procollagen in a case of perinatal lethal osteogenesis imperfecta (OI) type II. Cultured skin fibroblasts from the proband synthesized both normal and abnormal forms of type I procollagen. Some a
Publikováno v:
Archiv der Pharmazie. 340(5)
Design, synthesis, and cytotoxic activity of amidine derivatives of melphalan are described and structure-activity relationships are discussed. Evaluation of the cytotoxicity of these compounds employing a MTT assay and inhibition of [(3)H]thymidine
Publikováno v:
ChemInform. 34
Publikováno v:
Scopus-Elsevier
A series of amidine analogues of chlorambucil (9-12), where 5-[4-(N-alkylamidino)phenyl]-2-furancarboxamide and the chlorambucil moiety are linked by a NH(CH(2))(2)NH chain, was synthesized and their cytotoxicity has been tested against the growth of
Autor:
Ewa, Czeczuga-Semeniuk, Sławomir, Wołczyński, Tomasz, Anchim, Janusz, Dziecioł, Milena, Dabrowska, Mirosława, Pietruczuk
Publikováno v:
Polish journal of pathology : official journal of the Polish Society of Pathologists. 53(2)
Melatonin in the in vitro conditions inhibits cell growth and proliferation of estrogen sensitive (ER+) cell line MCF-7 in culture. In the present study, during a 48-hour incubation melatonin at a concentration of 10(-5) M inhibited [3H]thymidine inc