The N-terminal signature motif on the transporter MCT1 is critical for CD147-mediated trafficking.

Autor: Seka DJ; Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona, USA., Schulz AK; Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona, USA., Thaker TM; Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona, USA., Tomasiak TM; Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona, USA. Electronic address: tomasiak@arizona.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2024 Jun; Vol. 300 (6), pp. 107333. Date of Electronic Publication: 2024 May 22.

Cryo-EM structure of the tetra-phosphorylated R-domain in Ycf1 reveals key interactions for transport regulation.

Autor: de Carvalho RSA; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721., Rasel SI; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721., Khandelwal NK; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721.; Current Address: Department of Biochemistry and Biophysics, University of California - San Francisco, San Francisco, CA 94., Tomasiak TM; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Mar 24. Date of Electronic Publication: 2024 Mar 24.

Vaccines to Prevent Coccidioidomycosis: A Gene-Deletion Mutant of Coccidioides Posadasii as a Viable Candidate for Human Trials.

Autor: Galgiani JN; Valley Fever Center for Excellence, University of Arizona College of Medicine-Tucson, Tucson, AZ 85724, USA.; Department of Medicine, University of Arizona College of Medicine-Tucson, Tucson, AZ 85724, USA.; Department of Immunobiology, University of Arizona College of Medicine-Tucson, Tucson, AZ 85724, USA.; Bio5 Institute, University of Arizona, Tucson, AZ 85721, USA., Shubitz LF; Valley Fever Center for Excellence, University of Arizona College of Medicine-Tucson, Tucson, AZ 85724, USA., Orbach MJ; Valley Fever Center for Excellence, University of Arizona College of Medicine-Tucson, Tucson, AZ 85724, USA.; Bio5 Institute, University of Arizona, Tucson, AZ 85721, USA.; School of Plant Sciences, College of Agriculture and Life Sciences, University of Arizona, Tucson, AZ 85721, USA., Mandel MA; Valley Fever Center for Excellence, University of Arizona College of Medicine-Tucson, Tucson, AZ 85724, USA., Powell DA; Valley Fever Center for Excellence, University of Arizona College of Medicine-Tucson, Tucson, AZ 85724, USA., Klein BS; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53706, USA.; Department of Internal Medicine, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53706, USA.; Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53706, USA., Robb EJ; Anivive Lifesciences, Long Beach, CA 90807, USA., Ohkura M; Department of Botany and Plant Pathology, College of Agricultural Sciences, Oregon State University, Corvallis, OR 97331, USA., Seka DJ; Department of Chemistry and Biochemistry, College of Science, University of Arizona, Tucson, AZ 85721, USA., Tomasiak TM; Bio5 Institute, University of Arizona, Tucson, AZ 85721, USA.; Department of Chemistry and Biochemistry, College of Science, University of Arizona, Tucson, AZ 85721, USA., Monath TP; Crozet Biopharma LLC, Lexington, MA 02420, USA.

Publikováno v: Journal of fungi (Basel, Switzerland) [J Fungi (Basel)] 2022 Aug 10; Vol. 8 (8). Date of Electronic Publication: 2022 Aug 10.

Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter.

Autor: Thaker TM; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA., Mishra S; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.; St Jude Children's Research Hospital, Memphis, TN, USA., Zhou W; Theoretical Molecular Biophysics Laboratory, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Mohan M; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Tang Q; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Faraldo-Goméz JD; Theoretical Molecular Biophysics Laboratory, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Mchaourab HS; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA. hassane.mchaourab@vanderbilt.edu., Tomasiak TM; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA. tomasiak@arizona.edu.

Publikováno v: Nature chemical biology [Nat Chem Biol] 2022 Feb; Vol. 18 (2), pp. 226-235. Date of Electronic Publication: 2021 Dec 20.

The role of novel COQ8B mutations in glomerulopathy and related kidney defects.

Autor: AbuMaziad AS; Department of Pediatrics, Division of Nephrology, University of Arizona, Tucson, Arizona, USA., Thaker TM; Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona, USA., Tomasiak TM; Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona, USA., Chong CC; Department of Medicine, Division of Nephrology, University of Arizona, Tucson, Arizona, USA., Galindo MK; Center for Applied Genetics and Genomic Medicine and Department of Pediatrics, University of Arizona College of Medicine, Tucson, Arizona, USA., Hoyme HE; Center for Applied Genetics and Genomic Medicine and Department of Pediatrics, University of Arizona College of Medicine, Tucson, Arizona, USA.

Publikováno v: American journal of medical genetics. Part A [Am J Med Genet A] 2021 Jan; Vol. 185 (1), pp. 60-67. Date of Electronic Publication: 2020 Oct 20.