Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tomas Vikner"'
Autor:
Tomas Vikner, Kevin M. Johnson, Robert V. Cadman, Tobey J. Betthauser, Rachael E. Wilson, Nathaniel Chin, Laura B. Eisenmenger, Sterling C. Johnson, Leonardo A. Rivera-Rivera
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-11 (2024)
Abstract Background Cerebrospinal fluid (CSF) dynamics are increasingly studied in aging and neurological disorders. Models of CSF-mediated waste clearance suggest that altered CSF dynamics could play a role in the accumulation of toxic waste in the
Externí odkaz:
https://doaj.org/article/666e52bf2c404fdfa18dc835eca83698
Autor:
Tomas Vikner, Anders Garpebring, Cecilia Björnfot, Lars Nyberg, Jan Malm, Anders Eklund, Anders Wåhlin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Blood–brain barrier (BBB) disruption may contribute to cognitive decline, but questions remain whether this association is more pronounced for certain brain regions, such as the hippocampus, or represents a whole-brain mechanism. Further,
Externí odkaz:
https://doaj.org/article/3633223a451448a182f93b94b91daa36
Autor:
Lars Nyberg, Nina Karalija, Goran Papenberg, Alireza Salami, Micael Andersson, Robin Pedersen, Tomas Vikner, Douglas D. Garrett, Katrine Riklund, Anders Wåhlin, Martin Lövdén, Ulman Lindenberger, Lars Bäckman
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Cognitive functions are well-preserved for some older individuals, but the underlying brain mechanisms remain disputed. Here, 5-year longitudinal 3-back in-scanner and offline data classified individuals in a healthy older sample (baseline a
Externí odkaz:
https://doaj.org/article/43df79de146a44cc84de35d419a2fd9e
Autor:
Lars Bäckman, Anders Wahlin, Nina Karalija, Jan Malm, Tomas Vikner, Anders Eklund, Katrine Riklund, Ulman Lindenberger, Lars Nyberg
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism
Microvascular damage in the hippocampus is emerging as a central cause of cognitive decline and dementia in aging. This could be a consequence of age-related decreases in vascular elasticity, exposing hippocampal capillaries to excessive cardiac-rela
Autor:
Tomas Vikner, Nina Karalija, Anders Eklund, Jan Malm, Anders Lundquist, Nikodemus Gallewicz, Magnus Dahlin, Ulman Lindenberger, Katrine Riklund, Lars Bäckman, Lars Nyberg, Anders Wåhlin
Publikováno v:
Annals of Neurology
Objective: High cerebral arterial pulsatility index (PI), white matter lesions (WMLs), enlarged perivascular spaces (PVSs), and lacunar infarcts are common findings in the elderly population, and considered indicators of small vessel disease (SVD). H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a903ec2b0a6dee4c5c50664fea3855b
https://hdl.handle.net/21.11116/0000-000B-4F9F-B21.11116/0000-000A-D8B7-4
https://hdl.handle.net/21.11116/0000-000B-4F9F-B21.11116/0000-000A-D8B7-4
Publikováno v:
J Cereb Blood Flow Metab
Recent reports have suggested that age-related arterial stiffening and excessive cerebral arterial pulsatility cause blood–brain barrier breakdown, brain atrophy and cognitive decline. This has spurred interest in developing non-invasive methods to