Nucleophilic additions of chiral non-racemic enolates to N-benzyl-C-(alkoxymethyl) nitrones

Autor: Pedro Merino, Santiago Franco, Juan A. Mates, Francisco L. Merchan, Pilar Romero, Tomas Tejero, Santiago Uriel, Rosa Matute

Publikováno v: ARKIVOC, Vol 2004, Iss 4, Pp 48-58 (2003)

Externí odkaz: https://doaj.org/article/9de49e8cb2cd41e493256c504f58a19f

1,3-Dipolar Cycloadditions of N-Benzyl Furfuryl Nitrones with Electron-rich Alkenes

Autor: Tomas Tejero, Francisco L. Merchan, Sonia Anoro, Pedro Merino

Publikováno v: Molecules, Vol 5, Iss 2, Pp 132-152 (2000)

The 1,3-dipolar cycloaddition reaction of N-benzyl-C-(2-furyl)nitrones with electron-rich alkenes gives preferentially trans-substituted 3,5-disubstituted isoxazolidines (endo approach). These experimental results are in good qualitative agreement wi

Externí odkaz: https://doaj.org/article/25409cd0d09046f6ac43fc7dc2a097ad

Absence of intermediates in the BINOL-derived mg(ii)/phosphate-catalyzed desymmetrizative ring expansion of 1-Vinylcyclobutanols

Autor: Estefania Capel, Marta Rodríguez-Rodríguez, Uxue Uria, Manuel Pedron, Tomas Tejero, Jose L. Vicario, Pedro Merino

Publikováno v: Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Addi. Archivo Digital para la Docencia y la Investigación
The Journal of Organic Chemistry
Digital.CSIC. Repositorio Institucional del CSIC

The catalyzed desymmetrizative ring expansion of alkenylcyclobutanols promoted by halofunctionalization of the alkene moiety with N-bromosuccinimide has been experimentally and computationally studied. The reaction yields highly enantioenriched cyclo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0a4a3fdee7d2429624f4e6e6489be7
http://zaguan.unizar.es/record/112144

Computational studies of Brønsted acid-catalyzed transannular cycloadditions of cycloalkenone hydrazones

Autor: Manuel Pedrón, Jana Sendra, Irene Ginés, Tomás Tejero, Jose L. Vicario, Pedro Merino

Publikováno v: Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 477-486 (2023)

The contribution to the energy barrier of a series of tethers in transannular cycloadditions of cycloalkenes with hydrazones has been computationally studied by using DFT. The Houk's distortion model has been employed to evaluate the influence of the

Externí odkaz: https://doaj.org/article/3fcec1dd78d24d579e737e7584775486

An investigation of the Lewis acid mediated 1,3-dipolar cycloaddition between N-benzyl-C-(2-pyridyl)nitrone and allylic alcohol. Direct entry to isoxazolidinyl C-nucleosides

Autor: Pedro, Merino, Tomas, Tejero, Mariano, Laguna, Elena, Cerrada, Ana, Moreno, Jose A, Lopez

Publikováno v: Organicbiomolecular chemistry. 1(13)

The cycloaddition reaction of N-benzyl C-(2-pyridyl) nitrone with allylic alcohol has been carried out to obtain the corresponding 2-benzyl-3-(2-pyridyl)-5-hydroxymethylisoxazolidine. The influence of Lewis acids in the reaction has been studied and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f979529f9e387df86ef826485657c503
https://pubmed.ncbi.nlm.nih.gov/12945706