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Autor:
Tomas Slamka, Zdena Bartosova, Bujalkova M, Tomas Krivulcik, David Martinicky, Denisa Ilencikova, Katarina Zavodna
Publikováno v:
BMC Cancer, Vol 9, Iss 1, p 405 (2009)
BMC Cancer
BMC Cancer
Background Depending on the population studied, large genomic rearrangements (LGRs) of the mismatch repair (MMR) genes constitute various proportions of the germline mutations that predispose to hereditary non-polyposis colorectal cancer (HNPCC). It