Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tomas Paulenda"'
Autor:
Monika Bambouskova, Lucie Potuckova, Tomas Paulenda, Martina Kerndl, Denis A. Mogilenko, Kate Lizotte, Amanda Swain, Sebastian Hayes, Ryan D. Sheldon, Hyeryun Kim, Unnati Kapadnis, Abigail E. Ellis, Christine Isaguirre, Samantha Burdess, Anwesha Laha, Gaya K. Amarasinghe, Victor Chubukov, Thomas P. Roddy, Michael S. Diamond, Russell G. Jones, Donald M. Simons, Maxim N. Artyomov
Publikováno v:
Cell Reports, Vol 34, Iss 10, Pp 108756- (2021)
Summary: Itaconate is a unique regulatory metabolite that is induced upon Toll-like receptor (TLR) stimulation in myeloid cells. Here, we demonstrate major inflammatory tolerance and cell death phenotypes associated with itaconate production in activ
Externí odkaz:
https://doaj.org/article/dfbaa470a8684ff5a4d62690f4e0c2bb
Autor:
Viktor Bugajev, Tomas Paulenda, Pavol Utekal, Michal Mrkacek, Ivana Halova, Ladislav Kuchar, Ondrej Kuda, Petra Vavrova, Björn Schuster, Sergio Fuentes-Liso, Lucie Potuckova, Daniel Smrz, Sara Cernohouzova, Lubica Draberova, Monika Bambouskova, Petr Draber
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100121- (2021)
Leukotrienes (LTs) and sphingolipids are critical lipid mediators participating in numerous cellular signal transduction events and developing various disorders, such as bronchial hyperactivity leading to asthma. Enzymatic reactions initiating produc
Externí odkaz:
https://doaj.org/article/058a630f0eee440cb9b82b31fbd5f3ff
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
C-terminal Src kinase (CSK) is a major negative regulator of Src family tyrosine kinases (SFKs) that play critical roles in immunoreceptor signaling. CSK is brought in contiguity to the plasma membrane-bound SFKs via binding to transmembrane adaptor
Externí odkaz:
https://doaj.org/article/b1534bb8aa6147629b09b2f58b29c96f
Autor:
Lubica Draberova, Tomas Paulenda, Ivana Halova, Lucie Potuckova, Viktor Bugajev, Monika Bambouskova, Magda Tumova, Petr Draber
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144596 (2015)
Ethanol has multiple effects on biochemical events in a variety of cell types, including the high-affinity immunoglobulin E receptor (FcεRI) signaling in antigen-activated mast cells. However, the underlying molecular mechanism remains unknown. To g
Externí odkaz:
https://doaj.org/article/b80b828ae57f47ab897b2cee161bd25f
Autor:
Lucie Potuckova, Christine Isaguirre, Ryan D. Sheldon, Monika Bambouskova, Amanda Swain, Hyeryun Kim, Samantha Burdess, Maxim N. Artyomov, Martina Kerndl, Tomas Paulenda, Anwesha Laha, Abigail E. Ellis, Victor Chubukov, Michael S. Diamond, Sebastian Hayes, Unnati Kapadnis, Russell G. Jones, Kate Lizotte, Gaya K. Amarasinghe, Donald M. Simons, Thomas P. Roddy, Denis A. Mogilenko
Publikováno v:
Cell Reports, Vol 34, Iss 10, Pp 108756-(2021)
Summary: Itaconate is a unique regulatory metabolite that is induced upon Toll-like receptor (TLR) stimulation in myeloid cells. Here, we demonstrate major inflammatory tolerance and cell death phenotypes associated with itaconate production in activ
Autor:
Pavol Utekal, Lucie Potuckova, Lubica Dráberová, Tomas Paulenda, Michal Mrkacek, Ivana Halova, Ondrej Kuda, Monika Bambouskova, Petr Dráber, Petra Vavrova, Björn Schuster, Daniel Smrz, Viktor Bugajev, Sara Cernohouzova, Sergio Fuentes-Liso, Ladislav Kuchar
Publikováno v:
Journal of Lipid Research, Vol 62, Iss, Pp 100121-(2021)
Journal of Lipid Research
Journal of Lipid Research
Leukotrienes (LTs) and sphingolipids are critical lipid mediators participating in numerous cellular signal transduction events and developing various disorders, such as bronchial hyperactivity leading to asthma. Enzymatic reactions initiating produc
Autor:
Tomas Paulenda, Petr Dráber
Publikováno v:
Allergy. 71:918-930
A family of widely expressed ORM-like (ORMDL) proteins has been recently linked to asthma in genomewide association studies in humans and extensively explored in in vivo studies in mice. ORMDL proteins are key regulators of serine palmitoyltransferas
Autor:
Petr Draber, Tomas Paulenda, Pavol Utekal, Ivana Halova, Ladislav Kuchar, Ondrej Kuda, Petra Vavrova, Bjoern Schuster, Lucie Potuckova, Sara Cernohouzova, Lubica Draberova, Monika Bambouskova, Viktor Bugajev
Publikováno v:
The Journal of Immunology. 204:152.18-152.18
Leukotrienes and sphingolipids are critical lipid mediators participating in cellular signal transduction and development of various diseases. Metabolic pathways initiating production of these lipid mediators involve 5-lipoxygenase (5-LO)-mediated co
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, Vol 9 (2018)
C-terminal Src kinase (CSK) is a major negative regulator of Src family tyrosine kinases (SFKs) that play critical roles in immunoreceptor signaling. CSK is brought in contiguity to the plasma membrane-bound SFKs via binding to transmembrane adaptor
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, Vol 9 (2018)
Mast cells play an effector role in innate immunity, allergy, and inflammation. Antigen-mediated activation of mast cells initiates signaling events leading to Ca2+ response and the release of inflammatory and allergic mediators from granules. Diseas