Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tomas Muthny"'
Publikováno v:
Journal of Physiology and Biochemistry. 66:311-319
β-Hydroxy-β-methylbutyrate (HMB) is a leucine metabolite that may have a positive effect in protein catabolic conditions. Therefore, we hypothesized that HMB treatment could attenuate the sepsis-induced protein catabolic state. The aims of our stud
Autor:
Tilser I, Miroslav Kovarik, Ludek Sispera, Milan Holecek, Oleg V. Larionov, A. De Meijere, Tomas Muthny
Publikováno v:
ResearcherID
The proteasome inhibitors are used as research tools to study of the ATP-dependent ubiquitin-proteasome system. Some of them are at present undergoing clinical trials to be used as therapeutic agents for cancer or inflammation. These diseases are oft
Publikováno v:
Food and Chemical Toxicology. 47:255-259
Beta-hydroxy-beta-methylbutyrate (HMB) is a leucine metabolite with protein anabolic effect. The aim of the study was to examine the role of exogenous HMB on leucine and protein metabolism in whole body and selected tissues. Rats were administered by
Publikováno v:
International Journal of Experimental Pathology. 89:64-71
The aim of our study was to evaluate the differences in protein and amino acid metabolism after subcutaneous turpentine administration in the soleus muscle (SOL), predominantly composed of red fibres, and the extensor digitorum longus muscle (EDL) co
Publikováno v:
Journal of Parenteral and Enteral Nutrition. 30:467-473
Glutamine and branched-chain amino acids (BCAA; valine, leucine, and isoleucine) are used as nutrition supplements in the treatment of proteocatabolic illness. We hypothesized that simultaneous administration of BCAA and glutamine affects protein met
Publikováno v:
Biochemical and Biophysical Research Communications. 345:38-42
Proteasome inhibitors are novel therapeutic agents which may be used in treatment of cancer and other severe disorders. We studied the effect of proteasome inhibitor MG-132 on protein and amino acid metabolism. In MG-132-treated rats we observed a si
Publikováno v:
Journal of physiology and biochemistry. 68(3)
Endotoxin administration is frequently used as a model of systemic inflammatory response which is considered the important pathogenetic factor in muscle wasting development in severe illness, such as sepsis, cancer, injury, AIDS and others. The main
Autor:
Lucie, Vistejnova, Jana, Dvorakova, Martina, Hasova, Tomas, Muthny, Vladimir, Velebny, Karel, Soucek, Lukas, Kubala
Publikováno v:
Neuro endocrinology letters. 30
Determination of cell numbers is a crucial step in studies focused on cytokinetics and cell toxicity. The impedance-based analysis employing electronic sensor array system xCELLigence System allowing label-free dynamic monitoring of relative viable a
Publikováno v:
Clinical Nutrition Supplements. 3:200