Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Tomas Krizek"'
Publikováno v:
Molecules, Vol 27, Iss 12, p 3723 (2022)
Analysis of protein glycosylation is challenging due to micro- and macro-heterogeneity of the attached glycans. Hydrophilic interaction liquid chromatography (HILIC) is a mode of choice for separation of intact glycopeptides, which are inadequately r
Externí odkaz:
https://doaj.org/article/c4416fcdd2634f749a19295a635dd75a
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 153:687-695
Liposomes are nowadays a matter of tremendous interest. Due to their amphiphilic character, various substances with different properties can be incorporated into them and they are especially suitable as a model system for controlled transport of bioa
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 153:659-686
Glycosylation is one of the most significant and abundant post-translational modifications in cells. Glycomic and glycoproteomic analyses involve the characterization of oligosaccharides (glycans) conjugated to proteins. Glycomic and glycoproteomic a
Glycan-specific precipitation of glycopeptides in high organic content sample solvents used in HILIC
Publikováno v:
J Chromatogr B Analyt Technol Biomed Life Sci
The composition of a sample solvent has a crucial impact on separations in hydrophilic interaction liquid chromatography (HILIC). In this short communication, we studied the effect of an organic modifier in the sample solvent on the solubility of dif
Autor:
Jan Bosák, Martin Šíma, Tereza Krejčí, Iva Obadalová, Jaroslava Šmardová, Petr Kozlík, Tomáš Křížek, Josef Beránek, Tomáš Hauser, Ondřej Slanař
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 5, Pp n/a-n/a (2024)
Abstract The bioavailability of rivaroxaban at the higher doses (15 and 20 mg) is considerably reduced when the drug is administered on an empty stomach. This can lead to inadequate anticoagulant effect, and therefore, it is recommended to use the hi
Externí odkaz:
https://doaj.org/article/a5bac16325a84301bee9ca4ced8a4c8a
Autor:
Alena Libánská, Tomáš Špringer, Lucie Peštová, Kevin Kotalík, Rafał Konefał, Alice Šimonová, Tomáš Křížek, Jiří Homola, Eva Randárová, Tomáš Etrych
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Nanomedicines, including polymer nanocarriers with controlled drug release, are considered next-generation therapeutics with advanced therapeutic properties and reduced side effects. To develop safe and efficient nanomedicines, it is crucial
Externí odkaz:
https://doaj.org/article/f26bc3d23c05402cb6b63f3b3eeaded9
Autor:
Jiří Pozniak, Pavel Ryšánek, David Smrčka, Petr Kozlík, Tomáš Křížek, Jaroslava Šmardová, Anežka Nováková, Debanjan Das, Daniel Bobek, Mahak Arora, Jiří Hofmann, Tereza Doušová, Martin Šíma, Ondřej Slanař
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: Ivacaftor is a modern drug used in the treatment of cystic fibrosis. It is highly lipophilic and exhibits a strong positive food effect. These characteristics can be potentially connected to a pronounced lymphatic transport after oral adm
Externí odkaz:
https://doaj.org/article/a97021bba87c4ffb97563ac5f4adf948
Publikováno v:
Results in Chemistry, Vol 7, Iss , Pp 101336- (2024)
This article demonstrates the potential of electrochemical oxidation as an alternative approach to studying the effect of oxidation on active pharmaceutical ingredients. The performance and the outcomes of the electrochemical approach are compared to
Externí odkaz:
https://doaj.org/article/32b986cfd48e48689357b5b069df5e83
Autor:
Veronika Hýsková, Michal Jakl, Jana Jaklová Dytrtová, Sanja Ćavar Zeljković, Ondřej Vrobel, Kateřina Bělonožníková, Daniel Kavan, Tomáš Křížek, Alice Šimonová, Marie Vašková, Ishak Kovač, Antoniana Račko Žufić, Helena Ryšlavá
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 268, Iss , Pp 115729- (2023)
Several 1,2,4-triazoles are widely used as systemic fungicides in agriculture because they inhibit fungal 14ɑ-demethylase. However, they can also act on many non-target plant enzymes, thereby affecting phytohormonal balance, free amino acid content,
Externí odkaz:
https://doaj.org/article/f5d2cf4eac374ed59c93ff93a6ab9bee
Publikováno v:
International Journal of Business and Social Research, Vol 2, Iss 7, Pp 21-32 (2013)
Financial literacy is very important element of everybody’s life. Papers and studies usually focus on general public or lower-educated group of people but we think that university educated people should not be out of scope of work done in the field