Distinct HLA associations with autoantibody-defined subgroups in idiopathic inflammatory myopathiesResearch in context

Autor: Valérie Leclair, Angeles S. Galindo-Feria, Simon Rothwell, Olga Kryštůfková, Sepehr Sarrafzadeh Zargar, Herman Mann, Louise Pyndt Diederichsen, Helena Andersson, Martin Klein, Sarah Tansley, Lars Rönnblom, Kerstin Lindblad-Toh, Ann-Christine Syvänen, Marie Wahren-Herlenius, Johanna K. Sandling, Neil McHugh, Janine A. Lamb, Jiri Vencovský, Hector Chinoy, Marie Holmqvist, Matteo Bianchi, Leonid Padyukov, Ingrid E. Lundberg, Lina-Marcela Diaz-Gallo, Sergey V. Kozyrev, Maija-Leena Eloranta, Dag Leonard, Johanna Dahlqvist, Maria Lidén, Argyri Mathioudaki, Jennifer RS. Meadows, Jessika Nordin, Gunnel Nordmark, Antonella Notarnicola, Anna Tjärnlund, Maryam Dastmalchi, Daniel Eriksson, Øyvind Molberg, Fabiana H.G. Farias, Awat Jalal, Balsam Hanna, Helena Hellström, Tomas Husmark, Åsa Häggström, Anna Svärd, Thomas Skogh, Robert G. Cooper, Gerli Rosengren Pielberg, Anna Lobell, Åsa Karlsson, Eva Murén, Kerstin M. Ahlgren, Göran Andersson, Nils Landegren, Olle Kämpe, Peter Söderkvis

Publikováno v: EBioMedicine, Vol 96, Iss , Pp 104804- (2023)

Summary: Background: In patients with idiopathic inflammatory myopathies (IIM), autoantibodies are associated with specific clinical phenotypes suggesting a pathogenic role of adaptive immunity. We explored if autoantibody profiles are associated wit

Externí odkaz: https://doaj.org/article/f34c318e869f47ad9bf811500507e9f3

Active conventional treatment and three different biological treatments in early rheumatoid arthritis:phase IV investigator initiated, randomised, observer blinded clinical trial

Autor: Giovanni Cagnotto, Dan Nordström, Joakim Lindqvist, Lise Hyldstrup, Jon Lampa, Anna-Karin H. Ekwall, Gerdur Gröndal, Torkell Ellingsen, Tomas Husmark, Oliver Hendricks, Kim Hørslev-Petersen, Meliha C Kapetanovic, Daisy Vedder, Merete Lund Hetland, Marte Schrumpf Heiberg, Kristina Lend, Espen A Haavardsholm, David John Stevens, F. Faustini, Riitta Tuompo, Annika Soderbergh, T. Sokka-Isler, Tove Lorenzen, Per Larsson, Jos W. R. Twisk, Anna Rudin, Milad Rizk, Bjorn Gudbjornsson, Ronald F van Vollenhoven, Inge C. Olsen, M. T. Nurmohamed, Søren Andreas Just, Eli Brodin, Gunnstein Bakland, Mikkel Østergaard, Åsa Reckner Olsson, Line Uhrenholt, Kathrine Lederballe Grøn, Trine Bay Laurberg, Eva Baecklund, Simon Krabbe, Till Uhlig, Maud Kristine Aga Ljoså

Publikováno v: Hetland, M L, Haavardsholm, E A, Rudin, A, Nordström, D, Nurmohamed, M, Gudbjornsson, B, Lampa, J, Hørslev-Petersen, K, Uhlig, T, Grondal, G, Østergaard, M, Heiberg, M S, Twisk, J, Lend, K, Krabbe, S, Hyldstrup, L H, Lindqvist, J, Hultgård Ekwall, A K, Grøn, K L, Kapetanovic, M, Faustini, F, Tuompo, R, Lorenzen, T, Cagnotto, G, Baecklund, E, Hendricks, O, Vedder, D, Sokka-Isler, T, Husmark, T, Ljoså, M K A, Brodin, E, Ellingsen, T, Söderbergh, A, Rizk, M, Olsson, Å R, Larsson, P, Uhrenholt, L, Just, S A, Stevens, D J, Laurberg, T B, Bakland, G, Olsen, I C, van Vollenhoven, R & NORD-STAR Study Group 2020, ' Active conventional treatment and three different biological treatments in early rheumatoid arthritis : phase IV investigator initiated, randomised, observer blinded clinical trial ', B M J, vol. 371, m4328 . https://doi.org/10.1136/bmj.m4328
BMJ. British Medical Journal
BMJ (Clinical research ed.), 371:m4328. British Medical Association
Hetland, M L, Haavardsholm, E A, Rudin, A, Nordström, D, Nurmohamed, M, Gudbjornsson, B, Lampa, J, Hørslev-Petersen, K, Uhlig, T, Grondal, G, Østergaard, M, Heiberg, M S, Twisk, J, Lend, K, Krabbe, S, Hyldstrup, L H, Lindqvist, J, Hultgård Ekwall, A-K, Grøn, K L, Kapetanovic, M, Faustini, F, Tuompo, R, Lorenzen, T, Cagnotto, G, Baecklund, E, Hendricks, O, Vedder, D, Sokka-Isler, T, Husmark, T, Ljoså, M-K A, Brodin, E, Ellingsen, T, Söderbergh, A, Rizk, M, Olsson, Å R, Larsson, P, Uhrenholt, L, Just, S A, Stevens, D J, Laurberg, T B, Bakland, G, Olsen, I C, van Vollenhoven, R & NORD-STAR Study Group 2020, ' Active conventional treatment and three different biological treatments in early rheumatoid arthritis : phase IV investigator initiated, randomised, observer blinded clinical trial ', The BMJ, vol. 371, m4328 . https://doi.org/10.1136/bmj.m4328
Hetland, M L, Haavardsholm, E A, Rudin, A, Nordström, D, Nurmohamed, M, Gudbjornsson, B, Lampa, J, Hørslev-Petersen, K, Uhlig, T, Grondal, G, Østergaard, M, Heiberg, M S, Twisk, J, Lend, K, Krabbe, S, Hyldstrup, L H, Lindqvist, J, Hultgård Ekwall, A K, Grøn, K L, Kapetanovic, M, Faustini, F, Tuompo, R, Lorenzen, T, Cagnotto, G, Baecklund, E, Hendricks, O, Vedder, D, Sokka-Isler, T, Husmark, T, Ljoså, M K A, Brodin, E, Ellingsen, T, Söderbergh, A, Rizk, M, Olsson, Å R, Larsson, P, Uhrenholt, L, Just, S A, Stevens, D J, Laurberg, T B, Bakland, G, Olsen, I C & Van Vollenhoven, R 2020, ' Active conventional treatment and three different biological treatments in early rheumatoid arthritis : Phase IV investigator initiated, randomised, observer blinded clinical trial ', The BMJ, vol. 371, m4328 . https://doi.org/10.1136/bmj.m4328
The BMJ, 371:m4328
Hetland, M L, Haavardsholm, E A, Rudin, A, Nordström, D, Nurmohamed, M, Gudbjornsson, B, Lampa, J, Hørslev-Petersen, K, Uhlig, T, Grondal, G, Østergaard, M, Heiberg, M S, Twisk, J, Lend, K, Krabbe, S, Hyldstrup, L H, Lindqvist, J, Hultgård Ekwall, A K, Grøn, K L, Kapetanovic, M, Faustini, F, Tuompo, R, Lorenzen, T, Cagnotto, G, Baecklund, E, Hendricks, O, Vedder, D, Sokka-Isler, T, Husmark, T, Ljoså, M K A, Brodin, E, Ellingsen, T, Söderbergh, A, Rizk, M, Olsson, Å R, Larsson, P, Uhrenholt, L, Just, S A, Stevens, D J, Laurberg, T B, Bakland, G, Olsen, I C, van Vollenhoven, R & NORD-STAR study group 2020, ' Active conventional treatment and three different biological treatments in early rheumatoid arthritis : phase IV investigator initiated, randomised, observer blinded clinical trial ', BMJ (Clinical research ed.), vol. 371, m4328 . https://doi.org/10.1136/bmj.m4328
The BMJ

Objective To evaluate and compare benefits and harms of three biological treatments with different modes of action versus active conventional treatment in patients with early rheumatoid arthritis. Design Investigator initiated, randomised, open label

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1e4e2266731590418a688d446355fd
https://findresearcher.sdu.dk:8443/ws/files/175132336/bmj.m4328.full.pdf

OP0018 A MULTICENTER RANDOMIZED STUDY IN EARLY RHEUMATOID ARTHRITIS TO COMPARE ACTIVE CONVENTIONAL THERAPY VERSUS THREE BIOLOGICAL TREATMENTS: 24 WEEK EFFICACY RESULTS OF THE NORD-STAR TRIAL

Autor: Dan Nordström, Torkell Ellingsen, Kristina Lend, M.L. Hetland, Gerdur Gröndal, Bjorn Gudbjornsson, R. van Vollenhoven, Anna-Karin H. Ekwall, Oliver Hendricks, Espen A Haavardsholm, Maud-Kristine Aga Ljosa, F. Faustini, Annika Soderbergh, Eva Baecklund, Mikkel Ǿstergaard, Eli Brodin, Riitta Tuompo, T. Sokka-Isler, Inge C. Olsen, Å. Reckner, Line Uhrenholt, Simon Krabbe, Michael T. Nurmohamed, Daisy Vedder, Marte Schrumpf Heiberg, Tove Lorenzen, David John Stevens, Anna Rudin, Gunnstein Bakland, Milad Rizk, Giovanni Cagnotto, Joakim Lindqvist, Tomas Husmark, Per Larsson, Kim Hørslev-Petersen, Jos W. R. Twisk, Meliha C Kapetanovic, Søren Andreas Just, T. Uhlig, Jon Lampa, Kathrine Lederballe Grøn, Trine Bay Laurberg

Publikováno v: Annals of the Rheumatic Diseases. 79:13-14

Background:The optimal first-line treatment of patients (pts) with early rheumatoid arthritis (RA) is yet to be established.Objectives:The primary aim was to assess and compare the proportion of pts who achieved remission with active conventional the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::42bac2a53265459f6b91bedff620f22a
https://doi.org/10.1136/annrheumdis-2020-eular.689

DAPSA, DAS28 and MDA predict long-term treatment regime in psoriatic arthritis. The Swedish Early Psoriatic Arthritis Cohort

Autor: Ulla, Lindqvist, Mona-Lisa, Wernroth, Tomas, Husmark, Per, Larsson, Mats, Geijer, Annika, Teleman, Elke, Theander, Gerd-Marie, Alenius

Publikováno v: Clinical and experimental rheumatology. 35(6)

To describe treatment patterns in the Swedish early psoriatic arthritis cohort (SwePsA) of the mono-/oligo-arthritic (M/O) and polyarthritis (P) and identify early predictive factors for treatment with disease-modifying anti-rheumatic (DMARD), non-st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c91ccda1c89c79e2415b8598e3b1f842
https://pubmed.ncbi.nlm.nih.gov/28628468

The Swedish early psoriatic arthritis register-- 2-year followup: a comparison with early rheumatoid arthritis

Autor: Ulla R C, Lindqvist, Gerd-Marie, Alenius, Tomas, Husmark, Elke, Theander, Gunilla, Holmström, Per T, Larsson

Publikováno v: The Journal of rheumatology. 35(4)

Patients with symptoms and signs compatible with psoriatic arthritis (PsA), with or without psoriasis, have been documented in the Swedish Early Psoriatic Arthritis (SwePsA) register. Our aim was to find markers for disease progression and to evaluat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::79da9d00dabc82ea358ab8707eb63a0d
https://pubmed.ncbi.nlm.nih.gov/18278834