Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tomas Hejhal"'
Autor:
Ana Filipa Gonçalves, Mojca Adlesic, Simone Brandt, Tomas Hejhal, Sabine Harlander, Lukas Sommer, Olga Shakhova, Peter J. Wild, Ian J. Frew
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Renal angiomyolipomas (AML) contain a mix of clonal tumour cells. Here, through reverse tumour engineering experiments, mouse genetics and analyses of human AML tumours, the authors provide evidence that these mesenchymal tumours originate from renal
Externí odkaz:
https://doaj.org/article/7f63d8e6ed024233ba49cb91bfbd8004
Autor:
Antonella Catalano, Mojca Adlesic, Thorsten Kaltenbacher, Rhena F. U. Klar, Joachim Albers, Philipp Seidel, Laura P. Brandt, Tomas Hejhal, Philipp Busenhart, Niklas Röhner, Kyra Zodel, Kornelia Fritsch, Peter J. Wild, Justus Duyster, Ralph Fritsch, Tilman Brummer, Ian J. Frew
Publikováno v:
Cancers, Vol 13, Iss 8, p 1852 (2021)
Oncogenic mutations in RAS family genes arise frequently in metastatic human cancers. Here we developed new mouse and cellular models of oncogenic HrasG12V-driven undifferentiated pleomorphic sarcoma metastasis and of KrasG12D-driven pancreatic ducta
Externí odkaz:
https://doaj.org/article/847afd0f532a45c886ce0c5af605fd82
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186102 (2017)
The uterine corpus represents the most common site for tumour development in the female genital system. Uterine neoplasms are categorised as epithelial, mesenchymal, mixed epithelial-mesenchymal or trophoblastic tumours. In this study we employed a m
Externí odkaz:
https://doaj.org/article/af611dcad9dd4fdb8c9cb7f804c083a3
Autor:
Ian J. Frew, Carsten Lundby, Peter J. Wild, Tomas Hejhal, Mojca Adlesic, Anne-Kristine Lundby, Robert A. Jacobs, Michal Rajski, Sabine Harlander, Désirée Schönenberger
The von Hippel–Lindau (VHL) tumor suppressor gene is inactivated in the majority of clear cell renal cell carcinomas (ccRCC), but genetic ablation of Vhl alone in mouse models is insufficient to recapitulate human tumorigenesis. One function of pVH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d857117041850dfb65b2c73b4ef60af
https://doi.org/10.1158/0008-5472.c.6507929
https://doi.org/10.1158/0008-5472.c.6507929
Autor:
Ian J. Frew, Carsten Lundby, Peter J. Wild, Tomas Hejhal, Mojca Adlesic, Anne-Kristine Lundby, Robert A. Jacobs, Michal Rajski, Sabine Harlander, Désirée Schönenberger
Lists of Hif1a and Hif2a dependent genes induced by Vhl deletion in primary renal epithelial cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0e54454610f68cd5d6e2918eab19ea
https://doi.org/10.1158/0008-5472.22410152
https://doi.org/10.1158/0008-5472.22410152
Autor:
Ian J. Frew, Carsten Lundby, Peter J. Wild, Tomas Hejhal, Mojca Adlesic, Anne-Kristine Lundby, Robert A. Jacobs, Michal Rajski, Sabine Harlander, Désirée Schönenberger
Additional data related to histological analyses, establishing renal epithelial cell culture, analyses of microarray data and further analyses of Vhl/Trp53-, Vhl/Trp53/Hif1a- and Vhl/Trp53/Hif2a-deficient mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b000b6bb7b874066ad2e8ab5df5c24b
https://doi.org/10.1158/0008-5472.22410158.v1
https://doi.org/10.1158/0008-5472.22410158.v1
Autor:
Ian J. Frew, Carsten Lundby, Peter J. Wild, Tomas Hejhal, Mojca Adlesic, Anne-Kristine Lundby, Robert A. Jacobs, Michal Rajski, Sabine Harlander, Désirée Schönenberger
Contains figure legends for the Supplementary Figures S1-S8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1064f4e8c8765918b08b651ac9288a3e
https://doi.org/10.1158/0008-5472.22410161
https://doi.org/10.1158/0008-5472.22410161
Autor:
Ian J. Frew, Carsten Lundby, Peter J. Wild, Tomas Hejhal, Mojca Adlesic, Anne-Kristine Lundby, Robert A. Jacobs, Michal Rajski, Sabine Harlander, Désirée Schönenberger
Additional information related to antibodies, oligonucleotides, metabolic assays and respirometry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a97636c55af0156c357d79204df1b3f
https://doi.org/10.1158/0008-5472.22410155
https://doi.org/10.1158/0008-5472.22410155
Autor:
Ana Filipa Gonçalves, Tomas Hejhal, Antonella Catalano, Ian J. Frew, Svende Pfundstein, Laura P Brandt, Joachim Albers, Peter J. Wild
Publikováno v:
Oncotarget
Soft tissue sarcomas are rare mesenchymal tumours accounting for 1% of adult malignancies and are fatal in approximately one third of patients. Two of the most aggressive and lethal forms of soft tissue sarcomas are angiosarcomas and undifferentiated
Autor:
Michal Rajski, Robert A. Jacobs, Ian J. Frew, Anne-Kristine Meinild Lundby, Tomas Hejhal, Carsten Lundby, Sabine Harlander, Peter J. Wild, Mojca Adlesic, Désirée Schönenberger
Publikováno v:
Cancer research
The von Hippel–Lindau (VHL) tumor suppressor gene is inactivated in the majority of clear cell renal cell carcinomas (ccRCC), but genetic ablation of Vhl alone in mouse models is insufficient to recapitulate human tumorigenesis. One function of pVH