Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tomas Groh"'
Autor:
Yuriy Petrenko, Milada Chudickova, Irena Vackova, Tomas Groh, Eliska Kosnarova, Jitka Cejkova, Karolina Turnovcova, Alexander Petrenko, Eva Sykova, Sarka Kubinova
Publikováno v:
Stem Cells International, Vol 2019 (2019)
The wide use of human multipotent mesenchymal stromal cells (MSCs) in clinical trials requires a full-scale safety and identity evaluation of the cellular product and subsequent transportation between research/medical centres. This necessitates the p
Externí odkaz:
https://doaj.org/article/e74b66be2abb4b19b70e5cec5873ebd9
Autor:
Šárka Kubinová, Karolina Turnovcova, Yuriy A. Petrenko, Jitka Cejkova, Irena Vackova, Tomas Groh, Milada Chudíčková, Alexander Y. Petrenko, Eliska Kosnarova, Eva Syková
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Stem Cells International
Stem Cells International
The wide use of human multipotent mesenchymal stromal cells (MSCs) in clinical trials requires a full-scale safety and identity evaluation of the cellular product and subsequent transportation between research/medical centres. This necessitates the p
Autor:
Jan Hrabeta, Eva Frei, Helena Doktorova, Marie Stiborová, Tomas Groh, René Kizek, Jiri Uhlik, Mohamed Ashraf Khalil, Vojtech Adam, Tomas Eckschlager, Tereza Cerna, Jitka Poljaková
Publikováno v:
International journal of oncology. 47(3)
Neuroblastoma is the most common cancer in infants and the fourth most common cancer in children. Aggressive cell growth and chemoresistance are notorious obstacles in neuroblastoma therapy. Exposure to the anticancer drug ellipticine inhibits effici
Autor:
Mohammed Ashraf Khalil, Marie Stiborová, Jan Hrabeta, Tomas Groh, Helena Doktorova, Tomas Eckschlager
Publikováno v:
International journal of oncology. 47(1)
High-risk neuroblastoma remains one of the most important therapeutic challenges for pediatric oncologists. New agents or regimens are urgently needed to improve the treatment outcome of this fatal tumor. We examined the effect of histone deacetylase
Autor:
Tomas Eckschlager, Lucie Bořek‑Dohalská, Žaneta Omana Gudino, Tomas Groh, Helena Doktorova, Jan Hraběta, René Kizek, Marie Stiborová, Jitka Poljaková
Publikováno v:
Oncology reports. 31(4)
Cells of solid malignancies generally adapt to entire lack of oxygen. Hypoxia induces the expression of several genes, which allows the cells to survive. For DNA transcription, it is necessary that DNA structure is loosened. In addition to structural
Autor:
Tomas Eckschlager, Pavel Prochazka, Helena Doktorova, Mohamed Ashraf Khalil, Jan Hraběta, Tomas Groh
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162916 (2016)
PLoS ONE
PLoS ONE
Valproic acid (VPA) is a well-known antiepileptic drug that exhibits antitumor activities through its action as a histone deacetylase inhibitor. CD133 is considered to be a cancer stem cell marker in several tumors including neuroblastoma. CD133 tran
Publikováno v:
Neuro endocrinology letters. 33
Etoposide (Vepesid, VP-16), an inhibitor of topoisomerase II, is a chemotherapeutic drug commonly used for treatment of different types of malignant diseases. By inhibiting the topoisomerase II enzyme activity in cancer cells, this drug leads to DNA
Autor:
Patrick Polte, Tomas Gröhsler, Paul Kotterba, Lena von Nordheim, Dorothee Moll, Juan Santos, Paco Rodriguez-Tress, Yury Zablotski, Christopher Zimmermann
Publikováno v:
Frontiers in Marine Science, Vol 8 (2021)
Shallow estuaries, bays, and lagoons are generally considered hot spots of ocean productivity that often adjust rapidly to seasonal variations in atmospheric temperatures. During spring when biological reproductive processes begin in the temperate zo
Externí odkaz:
https://doaj.org/article/6d5ba9242143467388273692dd8a9cc2
Autor:
Mohamed Ashraf Khalil, Jan Hraběta, Tomáš Groh, Pavel Procházka, Helena Doktorová, Tomáš Eckschlager
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162916 (2016)
Valproic acid (VPA) is a well-known antiepileptic drug that exhibits antitumor activities through its action as a histone deacetylase inhibitor. CD133 is considered to be a cancer stem cell marker in several tumors including neuroblastoma. CD133 tran
Externí odkaz:
https://doaj.org/article/b1b3cf3f9c5c4093b1441c122357d8f1