Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Tomas Gonec"'
Autor:
Andrzej Bak, Jiri Kos, Gilles Degotte, Aleksandra Swietlicka, Tomas Strharsky, Dominika Pindjakova, Tomas Gonec, Adam Smolinski, Pierre Francotte, Michel Frederich, Violetta Kozik, Josef Jampilek
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3611 (2023)
A series of seventeen 4-chlorocinnamanilides and seventeen 3,4-dichlorocinnamanilides were characterized for their antiplasmodial activity. In vitro screening on a chloroquine-sensitive strain of Plasmodium falciparum 3D7/MRA-102 highlighted that 23
Externí odkaz:
https://doaj.org/article/0dc5f882afc74f9d96aec6749923e6f1
Autor:
Tomas Strharsky, Dominika Pindjakova, Jiri Kos, Lucia Vrablova, Pavel Smak, Hana Michnova, Tomas Gonec, Jan Hosek, Michal Oravec, Izabela Jendrzejewska, Alois Cizek, Josef Jampilek
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15090 (2022)
A series of thirty-two anilides of 3-(trifluoromethyl)cinnamic acid (series 1) and 4-(trifluoromethyl)cinnamic acid (series 2) was prepared by microwave-assisted synthesis. All the compounds were tested against reference strains Staphylococcus aureus
Externí odkaz:
https://doaj.org/article/d8c593c0c037450d9f72b8368464fa22
Autor:
Tomas Gonec, Lucia Vrablova, Dominika Pindjakova, Tomas Strharsky, Michal Oravec, Josef Jampilek
Publikováno v:
Chemistry Proceedings, Vol 12, Iss 1, p 28 (2022)
A series of twenty-two monosubstituted N-aryl-4-hydroxyquinoline-3-carboxanilides designed as dual anti-invasive agents was prepared and characterized. Lipophilicity significantly affects biological activities of compounds and ADME properties; theref
Externí odkaz:
https://doaj.org/article/8af370489ae143228517e73ed4a5ef00
Autor:
Jiri Kos, Gilles Degotte, Dominika Pindjakova, Tomas Strharsky, Timotej Jankech, Tomas Gonec, Pierre Francotte, Michel Frederich, Josef Jampilek
Publikováno v:
Molecules, Vol 27, Iss 22, p 7799 (2022)
Due to the urgent need of innovation in the antimalarial therapeutic arsenal, a series of thirty-seven ring-substituted N-arylcinnamanilides prepared by microwave-assisted synthesis were subjected to primary screening against the chloroquine-sensitiv
Externí odkaz:
https://doaj.org/article/168f27855ded41ada34cba2b3a7867c2
Autor:
Tomas Gonec, Dominika Pindjakova, Lucia Vrablova, Tomas Strharsky, Hana Michnova, Tereza Kauerova, Peter Kollar, Michal Oravec, Izabela Jendrzejewska, Alois Cizek, Josef Jampilek
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 715 (2022)
Pattern 1-hydroxy-N-(2,4,5-trichlorophenyl)-2-naphthamide and the thirteen original carbamates derived from it were prepared and characterized. All the compounds were tested against Staphylococcus aureus ATCC 29213 as a reference and quality control
Externí odkaz:
https://doaj.org/article/2c64d5829d484f489b761af2dfd8a399
Publikováno v:
Chemistry Proceedings, Vol 8, Iss 1, p 40 (2021)
2-Hydroxy-N-phenylnaphthalene-1-carboxamide, three fluoro monosubstituted and five fluoro disubstituted 2-hydroxynaphthalene-1-carboxanilides were prepared by microwave-assisted synthesis and characterized. All the compounds were evaluated for their
Externí odkaz:
https://doaj.org/article/6b6cecf575904535930ffae9247d0e41
Publikováno v:
Molecules, Vol 26, Iss 14, p 4336 (2021)
A set of twenty-four 3-hydroxynaphthalene-2-carboxanilides, disubstituted on the anilide ring by combinations of methoxy/methyl/fluoro/chloro/bromo and ditrifluoromethyl groups at different positions, was prepared. The compounds were tested for their
Externí odkaz:
https://doaj.org/article/810a17363b64449a97af11aba780fb86
Autor:
Andrzej Bak, Jiri Kos, Hana Michnova, Tomas Gonec, Sarka Pospisilova, Violetta Kozik, Alois Cizek, Adam Smolinski, Josef Jampilek
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6583 (2020)
A series of twenty-two novel N-(disubstituted-phenyl)-3-hydroxynaphthalene- 2-carboxamide derivatives was synthesized and characterized as potential antimicrobial agents. N-[3,5-bis(trifluoromethyl)phenyl]- and N-[2-chloro-5-(trifluoromethyl)phenyl]-
Externí odkaz:
https://doaj.org/article/64ea26f81f884131b359082e54a7c5eb
Autor:
Tomas Gonec, Jiri Kos, Eoghan Nevin, Rodney Govender, Matus Pesko, Jan Tengler, Ivan Kushkevych, Vendula Stastna, Michal Oravec, Peter Kollar, Jim O'Mahony, Katarina Kralova, Aidan Coffey, Josef Jampilek
Publikováno v:
Molecules, Vol 19, Iss 7, Pp 10386-10409 (2014)
In this study, a series of twenty-two ring-substituted naphthalene-1-carboxanilides were prepared and characterized. Primary in vitro screening of the synthesized carboxanilides was performed against Mycobacterium avium subsp. paratuberculosis. N-(2-
Externí odkaz:
https://doaj.org/article/6751b2c353e84eefbce4dbaef1816a85
Autor:
Katarina Kralova, Josef Jampilek, Aidan Coffey, Alois Cizek, Ales Imramovsky, Jim O'Mahony, Peter Kollar, Diogo Pereira, Barbara Chambel, Stanislava Keltosova, Matus Pesko, Rodney Govender, Iveta Zadrazilova, Jiri Kos, Tomas Gonec
Publikováno v:
Molecules, Vol 18, Iss 8, Pp 9397-9419 (2013)
In this study, a series of twenty-two ring-substituted 2-hydroxynaphthalene-1‑carboxanilides were prepared and characterized. Primary in vitro screening of the synthesized compounds was performed against Staphylococcus aureus, three methicillin-res
Externí odkaz:
https://doaj.org/article/34c3f6e8edb14ed98ce1e3e7a0d13dd7