Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tomas Forsberg"'
Publikováno v:
Journal of Clinical Nursing.
Autor:
Anna H. Persson, Sandra A.G. Visser, Lars B. Nilsson, Tomas Forsberg, Johan Gabrielsson, Anna Ollerstam, Jan-Arne Björkman, Ahmad Al-Saffar, Göran Duker
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 56:131-144
Introduction: The aim of the present study was to compare sensitivity in detecting the drug-induced QT interval prolongation in three dog models: conscious telemetered at sinus rhythm and conscious and anesthetized dogs during atrial pacing. The test
Autor:
Lars B. Nilsson, Göran Eklund, Stig Johan Wiklund, Göran Duker, Ahmad Al-Saffar, Tomas Forsberg, Johan Gabrielsson, Anna H. Persson, Anna Ollerstam, J. Magnus Fredriksson, Sandra A.G. Visser
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 55:35-48
Introduction: Drug-induced QT interval prolongation may lead to ventricular arrhythmias. The aim of the study was to optimize QT interval data processing to quantify drug-induced QT interval prolongation in the telemetry instrumented conscious dog mo
Two potentially protective responses to apnea were studied in obstructive sleep apnea (OSA) patients; the diving response and the increase in Hb concentration [Hb] via spleen contraction. Eight OSA patients and ten healthy controls performed apneas i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d9264efd896545dcecc8f3cf91848f
http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-25686
http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-25686
Autor:
Tomas Forsberg, Björn Sällström, Sandra A.G. Visser, Lambertus A. Peletier, Johan Gabrielsson
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 317:209-219
The aim of the present investigation was to develop a pharmacokinetic-pharmacodynamic model for the characterization of clomethiazole (CMZ)-induced hypothermia and the rapid development of long-lasting tolerance in rats while taking into account circ
Autor:
Björn Sällström, Ann-Christine Ericson, Lambertus A. Peletier, Johan Gabrielsson, Sandra A.G. Visser, Tomas Forsberg
Publikováno v:
Journal of Pharmacokinetics and Pharmacodynamics. 32:835-859
This study presents development and behaviour of a feedback turnover model that mimics asymmetric circadian oscillations of body temperature, blood pressure and heart rate in rats. The study also includes an application to drug-induced hypothermia, t
Autor:
Sofia Martinsson, Tomas Forsberg, Sandra A.G. Visser, Svante B. Ross, Johan Gabrielsson, Susanna Pozarek
Publikováno v:
European Journal of Pharmacology. 512:139-151
Mechanism, onset and duration of tolerance development to clomethiazole-induced hypothermia were investigated in rats using telemetry. The hypothermic effect of clomethiazole was completely abolished for 10 days after an s.c. injection of 300 micromo
Autor:
Anna Ollerstam, Sandra A.G. Visser, Lars B. Nilsson, Johan Gabrielsson, Ahmad Al-Saffar, Göran Duker, Stig Johan Wiklund, Anna H. Persson, Tomas Forsberg, Göran Eklund
Publikováno v:
Journal of pharmacological and toxicological methods. 53(2)
Introduction To assure drug safety, the investigation of the relationship between plasma concentration and drug-induced prolongation of the QT interval of the ECG is a challenge in drug discovery. For this purpose, dofetilide was utilized to demonstr
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 58:161-162
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 60:226