Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tomas Edgren"'
Autor:
Sofie Ekestubbe, Jeanette E Bröms, Tomas Edgren, Maria Fällman, Matthew S Francis, Ake Forsberg
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 6 (2016)
Type III secretion systems (T3SS) are dedicated to targeting anti-host effector proteins into the cytosol of the host cell to promote bacterial infection. Delivery of the effectors requires three specific translocator proteins, of which the hydrophil
Externí odkaz:
https://doaj.org/article/7b4a4e92e34545b8964089ccad79b6ed
Publikováno v:
PLoS Pathogens, Vol 8, Iss 5, p e1002669 (2012)
Externí odkaz:
https://doaj.org/article/db1c6165c0584d0398245268877d87c6
Autor:
Sara E Thorslund, Tomas Edgren, Jonas Pettersson, Roland Nordfelth, Mikael E Sellin, Ekaterina Ivanova, Matthew S Francis, Elin L Isaksson, Hans Wolf-Watz, Maria Fällman
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16784 (2011)
Many gram-negative bacteria use type III secretion systems to translocate effector proteins into host cells. These effectors interfere with cellular functions in a highly regulated manner resulting in effects that are beneficial for the bacteria. The
Externí odkaz:
https://doaj.org/article/f8575204e05b413b8a943f5318ca02bc
Yersinia pathogenicity depends mainly on a Type III Secretion System (T3SS) responsible for translocating effector proteins into the eukaryotic target cell cytosol. The T3SS is encoded on a 70 kb, low copy number virulence plasmid, pYV. A key T3SS re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe6da4856357c731f44cba6819432c8
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-208085
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-208085
Autor:
Stephan Schneiders, Maria Fällman, Anna Fahlgren, Tomas Edgren, Helen Wang, Kemal Avican, Tifaine Hechard
PathogenicYersinia spp.depend on the activity of a potent virulence plasmid-encodedysc/yoptype 3 secretion system (T3SS) to colonize hosts and cause disease. It was recently shown thatY. pseudotuberculosisup-regulates the virulence plasmid copy numbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c08f8cabe07e3697bf2aa888e5520ab
https://doi.org/10.1101/2020.11.04.369199
https://doi.org/10.1101/2020.11.04.369199
Publikováno v:
Journal of Biological Chemistry. 292:3299-3311
Many pathogenic Gram-negative bacteria use the type III secretion system (T3SS) to deliver effector proteins into eukaryotic host cells. In Yersinia the switch to secretion of effector proteins is ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9ab6a6dc1a3c6f1f6e8bf31e4f8e5f7
https://doi.org/10.1074/jbc.m116.770255
https://doi.org/10.1074/jbc.m116.770255
Publikováno v:
Methods in Molecular Biology ISBN: 9781493995400
Many Gram-negative pathogens produce a type III secretion system capable of intoxicating eukaryotic cells with immune-modulating effector proteins. Fundamental to this injection process is the prior secretion of two translocator proteins destined for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d79db6cad094a1b4a233aae59153eb35
https://doi.org/10.1007/978-1-4939-9541-7_15
https://doi.org/10.1007/978-1-4939-9541-7_15
Autor:
Ulrike Resch, Anetta Härtlova, Faizal A.M. Raffi, Maria Fällman, Saskia F. Erttmann, Nelson O. Gekara, Reza Rofougaran, Tomas Edgren, Ava Hosseinzadeh, Marta Sloniecka, Torben Ek
Publikováno v:
Immunity. 45:106-118
The ATM kinase is a central component of the DNA damage repair machinery and redox balance. ATM dysfunction results in the multisystem disease ataxia-telangiectasia (AT). A major cause of mortality in AT is respiratory bacterial infections. Whether A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b4947a8f80173010cd7e617db979787
https://doi.org/10.1016/j.immuni.2016.06.018
https://doi.org/10.1016/j.immuni.2016.06.018
Autor:
Tomas Edgren, Tiago R. D. Costa, Hans Wolf-Watz, Anna Fahlgren, Salah I. Farag, Ayad A. A. Amer, Maria Fällman, Matthew S. Francis
Publikováno v:
Cellular Microbiology. 15:1088-1110
Type III secretion enables bacteria to intoxicate eukaryotic cells with anti-host effectors. A class of secreted cargo are the two hydrophobic translocators that form a translocon pore in the host ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae93761432fc043ccbb4485b9c6cce5e
https://doi.org/10.1111/cmi.12100
https://doi.org/10.1111/cmi.12100
Publikováno v:
The Journal of biological chemistry. 292(8)
Many pathogenic Gram-negative bacteria use the type III secretion system (T3SS) to deliver effector proteins into eukaryotic host cells. In Yersinia, the switch to secretion of effector proteins is induced first after intimate contact between the bac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be7174ecc01021cff21584dd28e87b7e
https://pubmed.ncbi.nlm.nih.gov/28039361
https://pubmed.ncbi.nlm.nih.gov/28039361