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of 17
pro vyhledávání: '"Tomas Doyle"'
Autor:
Tomas Doyle
Publikováno v:
Journal of Virus Eradication, Vol 2, Iss 2, Pp 121-123 (2016)
Interferons (IFNs) are a family of pleiotropic cytokines that are released when viral infection is sensed by pattern recognition receptors. They induce an antiviral state in target cells through influencing the expression of hundreds of genes termed
Externí odkaz:
https://doaj.org/article/d45192ee5ddc489e95bf85db225afb6a
Autor:
Paul D Griffiths, Emily Rothwell, Mohammed Raza, Stephanie Wilmore, Tomas Doyle, Mark Harber, James O'Beirne, Stephen Mackinnon, Gareth Jones, Douglas Thorburn, Frank Mattes, Gaia Nebbia, Sowsan Atabani, Colette Smith, Anna Stanton, Vincent C Emery
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185298 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0163722.].
Externí odkaz:
https://doaj.org/article/99f9e060d65948cba7bd397c1fb8aa07
Autor:
Paul D Griffiths, Emily Rothwell, Mohammed Raza, Stephanie Wilmore, Tomas Doyle, Mark Harber, James O'Beirne, Stephen Mackinnon, Gareth Jones, Douglas Thorburn, Frank Mattes, Gaia Nebbia, Sowsan Atabani, Colette Smith, Anna Stanton, Vincent C Emery
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163722 (2016)
To help decide when to start and when to stop pre-emptive therapy for cytomegalovirus infection, we conducted two open-label randomized controlled trials in renal, liver and bone marrow transplant recipients in a single centre where pre-emptive thera
Externí odkaz:
https://doaj.org/article/a73f4fbee9444bdabe09a02f4054da3d
Autor:
Darja Pollpeter, Caroline Goujon, Marine Tauziet, Luis Apolonia, Maria Teresa Catanese, Boris Bonaventure, Tomas Doyle, Michael H. Malim, Marion Lussignol, Olivier Moncorgé
Publikováno v:
Doyle, T, Moncorgé, O, Bonaventure, B, Pollpeter, D, Lussignol, M, Tauziet, M, Apolonia, L, Catanese, M T, Goujon, C & Malim, M 2018, ' The interferon inducible isoform of NCOA7 inhibits endosome-mediated viral entry ', Nature Microbiology, vol. 3, no. 12, pp. 1369–1376 . https://doi.org/10.1038/s41564-018-0273-9
Nature Microbiology
Nature Microbiology, Nature Publishing Group, 2018, 3 (12), pp.1369-1376. ⟨10.1038/s41564-018-0273-9⟩
Nature Microbiology, 2018, 3 (12), pp.1369-1376. ⟨10.1038/s41564-018-0273-9⟩
Nature microbiology
Nature Microbiology
Nature Microbiology, Nature Publishing Group, 2018, 3 (12), pp.1369-1376. ⟨10.1038/s41564-018-0273-9⟩
Nature Microbiology, 2018, 3 (12), pp.1369-1376. ⟨10.1038/s41564-018-0273-9⟩
Nature microbiology
Interferons (IFNs) mediate cellular defence against viral pathogens by upregulation of interferon-stimulated genes (ISGs) whose products interact with viral components or alter cellular physiology to suppress viral replication (1–3). Among the ISGs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88dfa5a9b2797ca8ea5ab4dd2acafa6
https://kclpure.kcl.ac.uk/en/publications/6fd7a32e-7e6b-4fd8-add0-4f2accd52a34
https://kclpure.kcl.ac.uk/en/publications/6fd7a32e-7e6b-4fd8-add0-4f2accd52a34
Publikováno v:
Nat Rev Microbiol
The ability of interferons (IFNs) to inhibit HIV-1 replication in cell culture models has long been recognized, and the therapeutic administration of IFNα to HIV-1-infected patients who are not receiving antiretroviral therapy produces a clear but t
Autor:
Caroline Goujon, Tomas Doyle, Michael H. Malim, Wendy S. Barclay, Hélène Bauby, Olivier Moncorgé
Publikováno v:
Journal of Virology. 88:9017-9026
The myxovirus resistance 2 (MX2) protein of humans has been identified recently as an interferon (IFN)-inducible inhibitor of human immunodeficiency virus type 1 (HIV-1) that acts at a late postentry step of infection to prevent the nuclear accumulat
Autor:
Caroline Goujon, Michael H. Malim, Luis Apolonia, Darja Pollpeter, Olivier Moncorgé, Boris Bonaventure, Tomas Doyle, Maria-Teresa Catanese, Marion Lussignol, Marine Tauziet
Publikováno v:
Nature Microbiology. 4:539-539
In the version of Supplementary Fig. 5a originally published with this Letter, the authors mistakenly duplicated images of LAMP1 staining in place of CD63 staining; this has now been amended to the correct version shown below.
Autor:
Anna Maria Geretti, Tomas Doyle
Publikováno v:
Current Opinion in Infectious Diseases. 25:17-25
The source, significance and optimal management of low-level viraemia during highly active antiretroviral therapy (HAART) are poorly defined. This review highlights recent observations that have implications for clinical practice.The definition of lo
Autor:
Valentina Cambiano, Colette Smith, Margaret Johnson, Tomas Doyle, Paola Vitiello, Anna Maria Geretti, Andrew N. Phillips, Andrew Owen
Publikováno v:
Clinical Infectious Diseases. 54:724-732
Plasma human immunodeficiency virus type 1 (HIV-1) RNA suppression50 copies/mL is regarded as the optimal outcome of highly active antiretroviral therapy (HAART). Current viral load (VL) assays show increased sensitivity, but the significance of RNA
Autor:
Tomas Doyle, Anna Maria Geretti
Publikováno v:
Current Opinion in Infectious Diseases. 23:32-38
This review summarizes recent literature addressing immunization in the setting of HIV infection, with a specific focus on emerging evidence that can guide the care of HIV-positive adults.There are few controlled studies on the clinical efficacy and