Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Tomas Barrio"'
Autor:
Alba Marín-Moreno, Sylvie L. Benestad, Tomas Barrio, Laura Pirisinu, Juan Carlos Espinosa, Linh Tran, Alvina Huor, Michele Angelo Di Bari, Hasier Eraña, Ben C. Maddison, Claudia D’Agostino, Natalia Fernández-Borges, Sara Canoyra, Nuria Jerez-Garrido, Joaquín Castilla, John Spiropoulos, Keith Bishop, Kevin C. Gough, Romolo Nonno, Jorn Våge, Olivier Andréoletti, Juan María Torres
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-16 (2024)
Abstract The first case of CWD in a Norwegian red deer was detected by a routine ELISA test and confirmed by western blotting and immunohistochemistry in the brain stem of the animal. Two different western blotting tests were conducted independently
Externí odkaz:
https://doaj.org/article/51a3b8f500ba47a290cef12832a53307
Autor:
Christina D Orrú, Bradley R Groveman, Andrew G Hughson, Tomás Barrio, Kachi Isiofia, Brent Race, Natalia C Ferreira, Pierluigi Gambetti, David A Schneider, Kentaro Masujin, Kohtaro Miyazawa, Bernardino Ghetti, Gianluigi Zanusso, Byron Caughey
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1012175 (2024)
Prions or prion-like aggregates such as those composed of PrP, α-synuclein, and tau are key features of proteinopathies such as prion, Parkinson's and Alzheimer's diseases, respectively. Their presence on solid surfaces may be biohazardous under som
Externí odkaz:
https://doaj.org/article/e41f9f194a98464797ac114a7b488335
Detection of classical BSE prions in asymptomatic cows after inoculation with atypical/Nor98 scrapie
Autor:
Marina Betancor, Belén Marín, Alicia Otero, Carlos Hedman, Antonio Romero, Tomás Barrio, Eloisa Sevilla, Jean-Yves Douet, Alvina Huor, Juan José Badiola, Olivier Andréoletti, Rosa Bolea
Publikováno v:
Veterinary Research, Vol 54, Iss 1, Pp 1-7 (2023)
Abstract The emergence of bovine spongiform encephalopathy (BSE) prions from atypical scrapie has been recently observed upon experimental transmission to rodent and swine models. This study aimed to assess whether the inoculation of atypical scrapie
Externí odkaz:
https://doaj.org/article/2a677dd837164793b30505a9a15f2807
Autor:
Diego Sola, Marina Betancor, Paula A. Marco Lorente, Sonia Pérez Lázaro, Tomás Barrio, Eloisa Sevilla, Belén Marín, Bernardino Moreno, Marta Monzón, Cristina Acín, Rosa Bolea, Juan J. Badiola, Alicia Otero
Publikováno v:
Pathogens, Vol 12, Iss 12, p 1399 (2023)
Scrapie, a naturally occurring prion disease affecting goats and sheep, comprises classical and atypical forms, with classical scrapie being the archetype of transmissible spongiform encephalopathies. This review explores the challenges of scrapie di
Externí odkaz:
https://doaj.org/article/a09a68ca32cc40e7afbfe4f4d56f9e1e
Autor:
Alicia Otero, Tomás Barrio, Hasier Eraña, Jorge M Charco, Marina Betancor, Carlos M Díaz-Domínguez, Belén Marín, Olivier Andréoletti, Juan M Torres, Qingzhong Kong, Juan J Badiola, Rosa Bolea, Joaquín Castilla
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10, p e1010900 (2022)
The role of the glycosylation status of PrPC in the conversion to its pathological counterpart and on cross-species transmission of prion strains has been widely discussed. Here, we assessed the effect on strain characteristics of bovine spongiform e
Externí odkaz:
https://doaj.org/article/0b9b47e51bab4ad7aecf29df2bd11115
Autor:
Jean-Yves Douet, Alvina Huor, Hervé Cassard, Séverine Lugan, Naïma Aron, Chloé Mesic, Didier Vilette, Tomás Barrio, Nathalie Streichenberger, Armand Perret-Liaudet, Marie-Bernadette Delisle, Patrice Péran, Jean-Philippe Deslys, Emmanuel Comoy, Jean-Luc Vilotte, Katayoun Goudarzi, Vincent Béringue, Marcelo A. Barria, Diane L. Ritchie, James W. Ironside, Olivier Andréoletti
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-15 (2021)
Abstract Treatment with human pituitary-derived growth hormone (hGH) was responsible for a significant proportion of iatrogenic Creutzfeldt–Jakob disease (iCJD) cases. France and the UK experienced the largest case numbers of hGH-iCJD, with 122 and
Externí odkaz:
https://doaj.org/article/38331de11f744c59b42002fabad71f84
A Novel, Reliable and Highly Versatile Method to Evaluate Different Prion Decontamination Procedures
Autor:
Hasier Eraña, Miguel Ángel Pérez-Castro, Sandra García-Martínez, Jorge M. Charco, Rafael López-Moreno, Carlos M. Díaz-Dominguez, Tomás Barrio, Ezequiel González-Miranda, Joaquín Castilla
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Transmissible spongiform encephalopathies (TSEs) are a group of invariably fatal neurodegenerative disorders. The causal agent is an aberrantly folded isoform (PrPSc or prion) of the endogenous prion protein (PrPC) which is neurotoxic and amyloidogen
Externí odkaz:
https://doaj.org/article/3c7fb0c2119346d5957b782f69517a20
Autor:
Tomás Barrio, Enric Vidal, Marina Betancor, Alicia Otero, Inmaculada Martín-Burriel, Marta Monzón, Eva Monleón, Martí Pumarola, Juan José Badiola, Rosa Bolea
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2714 (2021)
Neurotrophins constitute a group of growth factor that exerts important functions in the nervous system of vertebrates. They act through two classes of transmembrane receptors: tyrosine-kinase receptors and the p75 neurotrophin receptor (p75NTR). The
Externí odkaz:
https://doaj.org/article/007e5c07bf974aa4b50a76ee9707a4d9
Autor:
Isabel M. Guijarro, Moisés Garcés, Pol Andrés-Benito, Belén Marín, Alicia Otero, Tomás Barrio, Margarita Carmona, Isidro Ferrer, Juan J. Badiola, Marta Monzón
Publikováno v:
Biomolecules, Vol 11, Iss 2, p 204 (2021)
The actual role of prion protein-induced glial activation and subsequent cytokine secretion during prion diseases is still incompletely understood. The overall aim of this study is to assess the effect of an anti-inflammatory treatment with dexametha
Externí odkaz:
https://doaj.org/article/0a23dc48962242a480362e13fec00973
Autor:
Isabel M. Guijarro, Moisés Garcés, Belén Marín, Alicia Otero, Tomás Barrio, Juan J. Badiola, Marta Monzón
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 16, p 5779 (2020)
A recently published report on chronic dexamethasone treatment for natural scrapie supported the hypothesis of the potential failure of astroglia in the advanced stage of disease. Herein, we aimed to extend the aforementioned study on the effect of t
Externí odkaz:
https://doaj.org/article/aec970ec83f1442d8dbfae2c9649da84