Dabigatran etexilate for the treatment of acute venous thromboembolism in children (DIVERSITY): a randomised, controlled, open-label, phase 2b/3, non-inferiority trial

Autor: Jacqueline Halton, Leonardo R Brandão, Matteo Luciani, Lisa Bomgaars, Elizabeth Chalmers, Lesley G Mitchell, Ildar Nurmeev, Anjali Sharathkumar, Pavel Svirin, Kirill Gorbatikov, Igor Tartakovsky, Monika Simetzberger, Fenglei Huang, Zhichao Sun, Jörg Kreuzer, Savion Gropper, Paul Reilly, Martina Brueckmann, Manuela Albisetti, Asiya Safina, Ondrej Zapletal, Tomas Kuhn, Tomas Votava, Judy Felgenhauer, Ali Amid, Paola Saracco, Csongor Kiss, Susan Halimeh, Madlen Reschke, Beate Wulff, Michele David, Zbynek Novak, Inna Trunina, Tony Frisk, Heidi Glosli, Andreas Groll, Olga Lvova, Ilgen Sasmaz, Darintr Sosothikul, Virginija Zilinskaite, Erin Cockrell, Valeriy Digtyar, Ivana Hadacova, Sauli Palmu, Anjali Pawar, Joyce Maria Annichino Bizzacchi, Umran Caliskan, Tiraje Celkan, Dmytro Dmytriiev, Colleen Harkins Druzgal, Graciela Onelda Elena, Antonis Kattamis, Ramazan Kaan Kavakli, Christoph Male, Nihal Ozdemir, An Van Damme, Tatiana Zvereva, Aanen Aarli, Rogelio Alejandro Paredes Aguilera, Selin Aytac, Jorge Carneiro, Antonio Chistolini, Maria Gabriela Mazzucconi, Fernando Corrales-Medina, Francis Couturaud, Stacey E Croteau, Cameron Trenor III, Michael Damgaard, Natalia Dixon, Anna Galustyan, Jiri Hak, Marianne Hoffmann, Alphan Kupesiz, Veerle Labarque, Christel van Geet, Ming-Chih Lin, Yun-Ching Fu, Sandra Loggetto, Veerle Mondelaers, Irena Odri-Komazec, Shoshana Revel-Vilk, Julian Sevilla, Luciano Fuzzato Silva, José Kerr Saraiva, Fernando Felix Montes Tapia, Wendy Woods-Swafford

Publikováno v: The Lancet. Haematology, Vol. 8, no.1, p. e22-e33 (2021)

BACKGROUND: Dabigatran etexilate is a direct oral anticoagulant with potential to overcome the limitations of standard of care in children with venous thromboembolism. The aims of this clinical trial were to study the appropriateness of a paediatric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6576a5afe58bf10852f806c3c8eb49
https://hdl.handle.net/2078.1/260410

First 2 cases with thiamine-responsive megaloblastic anemia in the Czech Republic, a rare form of monogenic diabetes mellitus: a novel mutation in the thiamine transporter SLC19A2 gene-intron 1 mutation c.204+2T>G

Autor: Jiří Dort, Zdeňka Černá, Ivan Subrt, Jana Zamboryová, Václav Lád, Eva Dortová, Karel Fiklík, Josef Sýkora, Petr Jehlička, Petra Paterová, Renata Pomahačová, Tomas Votava

Publikováno v: Pediatric Diabetes. 18:844-847

Thiamine-responsive megaloblastic anemia (TRMA) is a rare autosomal recessive disorder caused by mutations in the SLC19A2 gene. To date at least 43 mutations have been reported for the gene encoding a plasma membrane thiamine transporter protein (THT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2aa740a49e33beaecc8bdc884f936666
https://doi.org/10.1111/pedi.12479

P5.05 REACTIVE HYPEREMIA INDEX AND DETECTION OF ENDOTHELIAL DYSFUNCTION IN CHILDREN

Autor: Tomas Votava, Michal Huml, J. Kobr, Petr Jehlička

Publikováno v: Artery Research, Vol 4, Iss 4 (2010)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a6c4247782b3dde527a18b7e818d9a
https://www.atlantis-press.com/article/125929394/view

Identification of a new in-frame deletion of six amino acids in ribosomal protein S19 in a patient with Diamond-Blackfan anemia

Autor: Jana Cmejlova, Dagmar Pospisilova, Tomas Votava, Radek Cmejla, Zdena Cerna

Publikováno v: Blood cells, moleculesdiseases. 36(3)

Ribosomal protein S19 ( RPS19 ) is currently the only gene associated with Diamond-Blackfan anemia (DBA), a rare congenital pure red cell aplasia characterized by normochromic macrocytic anemia, reticulocytopenia, and normocellular bone marrow with a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::887e8b8b3a4c34b6e397fd2c2a123f6f
https://pubmed.ncbi.nlm.nih.gov/16531079

P8.05 REACTIVE HYPEREMIA INDEX AND DETECTION OF ENDOTHELIAL DYSFUNCTION IN PAEDIATRIC HEMATO/ONCOLOGY PATIENTS

Autor: Petr Jehlička, Tomas Votava, J. Kobr, Michal Huml

Publikováno v: Artery Research, Vol 5, Iss 4 (2011)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f03cada9c6def3d7eb64551cf22d24a
https://doi.org/10.1016/j.artres.2011.10.127