Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Tomas, Strandin"'
Autor:
Luz E. Cabrera, Cienna Buckner, Veronica Then, Sanna Mäki, Olli Vapalahti, Antti Vaheri, Jussi Hepojoki, Johanna Tietäväinen, Satu Mäkelä, Jukka Mustonen, Tomas Strandin
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Old World Orthohantaviruses cause hemorrhagic fever with renal syndrome (HFRS) characterized by increased vascular permeability and acute kidney injury (AKI). Despite the systemic nature of the disease, the virus enters humans through inhalation and
Externí odkaz:
https://doaj.org/article/e6a9904351c1449caff1047639d20e12
Autor:
Luz E Cabrera, Suvi T Jokiranta, Sanna Mäki, Simo Miettinen, Ravi Kant, Lauri Kareinen, Tarja Sironen, Jukka-Pekka Pietilä, Anu Kantele, Eliisa Kekäläinen, Hanna Lindgren, Pirkko Mattila, Anja Kipar, Olli Vapalahti, Tomas Strandin
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012368 (2024)
The severity of COVID-19 is linked to excessive inflammation. Neutrophils represent a critical arm of the innate immune response and are major mediators of inflammation, but their role in COVID-19 pathophysiology remains poorly understood. We conduct
Externí odkaz:
https://doaj.org/article/d08c9a0c6bf14abc8cfd31ca9ef6a0ed
Autor:
Marina García, Anna Carrasco García, Whitney Weigel, Wanda Christ, Ronaldo Lira-Junior, Lorenz Wirth, Johanna Tauriainen, Kimia Maleki, Giulia Vanoni, Antti Vaheri, Satu Mäkelä, Jukka Mustonen, Johan Nordgren, Anna Smed-Sörensen, Tomas Strandin, Jenny Mjösberg, Jonas Klingström
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012390 (2024)
Hantaviruses cause the acute zoonotic diseases hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Infected patients show strong systemic inflammation and immune cell activation. NK cells are highly activated in HFRS
Externí odkaz:
https://doaj.org/article/20bc63d9ae5a4700b41d8af98795e89a
Autor:
Luz E. Cabrera, Johanna Tietäväinen, Suvi T. Jokiranta, Satu Mäkelä, Antti Vaheri, Jukka Mustonen, Olli Vapalahti, Mari Kanerva, Tomas Strandin
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Puumala orthohantavirus-caused hemorrhagic fever with renal syndrome (PUUV-HFRS) is characterized by strong neutrophil activation. Neutrophils are the most abundant immune cell type in the circulation and are specially equipped to rapidly respond to
Externí odkaz:
https://doaj.org/article/f7cefbbd26e74301a8b96906d0789b61
Publikováno v:
Viruses, Vol 16, Iss 10, p 1591 (2024)
The articles in this Special Issue, “Hantavirus Research in Finland”, were published between 2021 and 2022 [...]
Externí odkaz:
https://doaj.org/article/d8183ea3ed7c4ea0ba6bb636d509f186
Autor:
Liina Hannula, Suvi Kuivanen, Jonathan Lasham, Ravi Kant, Lauri Kareinen, Mariia Bogacheva, Tomas Strandin, Tarja Sironen, Jussi Hepojoki, Vivek Sharma, Petri Saviranta, Anja Kipar, Olli Vapalahti, Juha T. Huiskonen, Ilona Rissanen
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 4 (2024)
ABSTRACTIn response to the ongoing COVID-19 pandemic, the quest for coronavirus inhibitors has inspired research on a variety of small proteins beyond conventional antibodies, including robust single-domain antibody fragments, i.e., “nanobodies.”
Externí odkaz:
https://doaj.org/article/cecbf8f257de4f2482e0413c26276bab
Autor:
Xiaobo Huang, Jonas Kantonen, Kirsten Nowlan, Ngoc Anh Nguyen, Suvi T. Jokiranta, Suvi Kuivanen, Nelli Heikkilä, Shamita Mahzabin, Anu Kantele, Olli Vapalahti, Liisa Myllykangas, Santtu Heinonen, Mikko I. Mäyränpää, Tomas Strandin, Eliisa Kekäläinen
Publikováno v:
Virus Research, Vol 341, Iss , Pp 199315- (2024)
Prolonged T cell lymphopenia is common in COVID-19, caused by SARS-CoV-2. While the mechanisms of lymphopenia during COVID-19 remain elusive, it is especially pronounced in a specialized innate-like T cell population called Mucosal Associated Invaria
Externí odkaz:
https://doaj.org/article/a896fc2014e74f6486d979727fa98e2c
Autor:
Sohvi Kääriäinen, Jukka Ollgren, Timothee Dub, Outi Laine, Marjatta Sinisalo, Jussi Hepojoki, Tomas Strandin, Eliisa Kekäläinen, Jussi Sane, Outi Lyytikäinen
Publikováno v:
International Journal of Infectious Diseases, Vol 131, Iss , Pp 1-6 (2023)
Objectives: The Puumala virus (PUUV) is a hantavirus that causes hemorrhagic fever with renal syndrome. Studies showing an increased risk of lymphoid malignancies after hantavirus infection, together with the observation that PUUV infects B cells, mo
Externí odkaz:
https://doaj.org/article/cbb173e785ff4836ae827c62354763b4
Autor:
Anna R. Mäkelä, Hasan Uğurlu, Liina Hannula, Ravi Kant, Petja Salminen, Riku Fagerlund, Sanna Mäki, Anu Haveri, Tomas Strandin, Lauri Kareinen, Jussi Hepojoki, Suvi Kuivanen, Lev Levanov, Arja Pasternack, Rauno A. Naves, Olli Ritvos, Pamela Österlund, Tarja Sironen, Olli Vapalahti, Anja Kipar, Juha T. Huiskonen, Ilona Rissanen, Kalle Saksela
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Here the authors describe a small antibody-like protein that can prevent infection by diverse SARS-CoV-2 variants in cell culture and in mice that were intranasally treated with this inhibitor before or shortly after being exposed to the virus.
Externí odkaz:
https://doaj.org/article/326654b56d2c4bd89b56074f0855fd2f
Autor:
Jenni Virtanen, Kirsi Aaltonen, Kristel Kegler, Vinaya Venkat, Thanakorn Niamsap, Lauri Kareinen, Rasmus Malmgren, Olga Kivelä, Nina Atanasova, Pamela Österlund, Teemu Smura, Antti Sukura, Tomas Strandin, Lara Dutra, Olli Vapalahti, Heli Nordgren, Ravi Kant, Tarja Sironen
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 6, Pp 1286-1288 (2022)
We report an experimental infection of American mink with SARS-CoV-2 Omicron variant and show that mink remain positive for viral RNA for days, experience clinical signs and histopathologic changes, and transmit the virus to uninfected recipients. Pr
Externí odkaz:
https://doaj.org/article/27838fc2a4e6443399222da568473deb