Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Tomas, Perecko"'
Autor:
Jana Pereckova, Silvia Martiniakova, Juraj Payer, Martin Falk, Zdenko Killinger, Tomas Perecko
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 21, Pp 580-594 (2022)
Administration of biological therapy (BT) in rheumatoid arthritis (RA) patients is often associated with hematological complications, which result in switching among therapies. Thus, there is an instant need for suitable screening parameters that wil
Externí odkaz:
https://doaj.org/article/186326ca42464d5d93efac113a1d3a21
Publikováno v:
ACS Applied Nano Materials. 5:13267-13275
Autor:
Jana Pereckova, Michaela Pekarova, Nikoletta Szamecova, Zuzana Hoferova, Kristyna Kamarytova, Martin Falk, Tomas Perecko
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9981 (2021)
Nitro-oleic acid (NO2-OA), pluripotent cell-signaling mediator, was recently described as a modulator of the signal transducer and activator of transcription 3 (STAT3) activity. In our study, we discovered new aspects of NO2-OA involvement in the reg
Externí odkaz:
https://doaj.org/article/b68695ed57fb42ee96c4c4ff608ed3d0
Publikováno v:
Life sciences. 310
Limited number of agents that provide protection against hematopoietic acute radiation syndrome led us to the evaluation of nitro-oleic acid (NONOOur results show that NOIn conclusion, our data show that NO
Autor:
Nikoletta Szamecova, Tomas Perecko, Jana Pereckova, Michaela Pekarova, Kristyna Kamarytova, Martin Falk, Zuzana Hoferová
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9981, p 9981 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 18
International Journal of Molecular Sciences
Volume 22
Issue 18
Nitro-oleic acid (NO2-OA), pluripotent cell-signaling mediator, was recently described as a modulator of the signal transducer and activator of transcription 3 (STAT3) activity. In our study, we discovered new aspects of NO2-OA involvement in the reg
Autor:
Jaroslav Kočišek, Nail L. Asfandiarov, Martin Falk, Thomas F. M. Luxford, Stanislav A. Pshenichnyuk, Tomas Perecko
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 8173, p 8173 (2020)
Volume 21
Issue 21
International Journal of Molecular Sciences, Vol 21, Iss 8173, p 8173 (2020)
Volume 21
Issue 21
We report experimental results of low-energy electron interactions with 5-nitro-2,4-dichloropyrimidine isolated in the gas phase and hydrated in a cluster environment. The molecule exhibits a very rare combination of many so far hypothesized low-ener
Publikováno v:
Interdisciplinary Toxicology
Interdisciplinary Toxicology, Vol 10, Iss 2, Pp 61-65 (2017)
Interdisciplinary Toxicology, Vol 10, Iss 2, Pp 61-65 (2017)
The health benefits of berberine have been recognized for years. Even so, its effects on human neutrophils, the first line of immune defense, have not been reported. The purpose of this study was to investigate the effects of berberine on the human n
Autor:
Ondřej Hylse, Jakub Švenda, Tomas Perecko, Aneta Svobodová, Roman Kučera, Kamil Paruch, Lukáš Kubala, Lukáš Maier
Publikováno v:
Angewandte Chemie International Edition. 56:12586-12589
A 24-step synthesis of (±)-forskolin is presented, which delivered hundred milligram quantities of this complex diterpene in one pass. Transformations key to our approach include: a) a strategic allylic transposition, b) stepwise assembly of a steri
Autor:
Michaela Pekarova, Gabriela Ambrozova, Adolf Koudelka, Ondrej Vasicek, Steven R. Woodcock, Tanja K. Rudolph, Hana Verescakova, Tomas Perecko, Anna Klinke, Lukáš Kubala, Bruce A. Freeman
Publikováno v:
Free Radical Biology and Medicine. 104:10-19
Many diseases accompanied by chronic inflammation are connected with dysregulated activation of macrophage subpopulations. Recently, we reported that nitro-fatty acids (NO2-FAs), products of metabolic and inflammatory reactions of nitric oxide and ni
Autor:
Jason P. Eiserich, Tomas Perecko, Stephan Baldus, Silvie Kremserová, Lukáš Kubala, Anna Klinke, Karel Souček
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2016 (2016)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Systemic inflammation accompanying diseases such as sepsis affects primarily lungs and induces their failure. This remains the most common cause of sepsis induced mortality. While neutrophils play a key role in pulmonary failure, the mechanisms remai