Výsledky vyhledávání - "Tomas, Olejar"

Akademický článek

Biomarkers Analysis and Clinical Manifestations in Comorbid Creutzfeldt–Jakob Disease: A Retrospective Study in 215 Autopsy Cases

Autor: Nikol Jankovska, Robert Rusina, Jiri Keller, Jaromir Kukal, Magdalena Bruzova, Eva Parobkova, Tomas Olejar, Radoslav Matej

Publikováno v: Biomedicines, Vol 10, Iss 3, p 680 (2022)

Creutzfeldt–Jakob disease (CJD), the most common human prion disorder, may occur as “pure” neurodegeneration with isolated prion deposits in the brain tissue; however, comorbid cases with different concomitant neurodegenerative diseases have be

Externí odkaz: https://doaj.org/article/12872e8d15424f4893994aa58940fd61

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Akademický článek

Human Prion Disorders: Review of the Current Literature and a Twenty-Year Experience of the National Surveillance Center in the Czech Republic

Autor: Nikol Jankovska, Robert Rusina, Magdalena Bruzova, Eva Parobkova, Tomas Olejar, Radoslav Matej

Publikováno v: Diagnostics, Vol 11, Iss 10, p 1821 (2021)

Human prion disorders (transmissible spongiform encephalopathies, TSEs) are unique, progressive, and fatal neurodegenerative diseases caused by aggregation of misfolded prion protein in neuronal tissue. Due to the potential transmission, human TSEs a

Externí odkaz: https://doaj.org/article/760cf9e50f9e4926824bcfb6b79e2ff8

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PAR2: The Cornerstone of Pancreatic Diseases

Autor: Suhaj P, Tomas Olejar, Matej R

Publikováno v: Physiol Res
Europe PubMed Central

It has been 30 years since the first member of the protease-activated receptor (PAR) family was discovered. This was followed by the discovery of three other receptors, including PAR2. PAR2 is a G protein-coupled receptor activated by trypsin site-sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b146f965f05809fa58e9a5323bf8b8
https://europepmc.org/articles/PMC9841802/

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Unexpected infiltration of meninges by generalised diffuse large B-cell lymphoma manifesting as multiple cranial neuropathies in a patient with history of breast carcinoma

Autor: Ondřej Sobek, Adam Pavličko, Eva Malá, Radoslav Matěj, Robert Rusina, Tomas Olejar, Kateřina Matějová

Publikováno v: Neurologia i Neurochirurgia Polska. 55:499-501

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b30a8cda56015bdf46e91eacd5c3710
https://doi.org/10.5603/pjnns.a2021.0049

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Different Morphology of Neuritic Plaques in the Archicortex of Alzheimer’s Disease with Comorbid Synucleinopathy: A Pilot Study

Autor: Jaromir Kukal, Nikol Jankovska, Radoslav Matej, Tomas Olejar

Publikováno v: Current Alzheimer Research. 17:948-958

Background: Bulbous neuritic changes in neuritic plaques have already been described, and their possible effect on the clinical course of the disease has been discussed. Objective: In our study, we focused on the location and density of these structu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0123305906ec2690414d556ec85ec1
https://doi.org/10.2174/1875692117999201215162043

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Extracellular Prion Protein Aggregates in Nine Gerstmann–Sträussler–Scheinker Syndrome Subjects with Mutation P102L: A Micromorphological Study and Comparison with Literature Data

Autor: Tomas Olejar, Radoslav Matej, Nikol Jankovska

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 13303, p 13303 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13303

Gerstmann–Sträussler–Scheinker syndrome (GSS) is a hereditary neurodegenerative disease characterized by extracellular aggregations of pathological prion protein (PrP) forming characteristic plaques. Our study aimed to evaluate the micromorpholo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33035cb7759434410735efe7f5776af7
https://www.mdpi.com/1422-0067/22/24/13303

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The FSHR Expression in Head and Neck Squamous Cell Cancer. A Pilot Immunohistochemical Study

Autor: Michal Zabrodsky, Pavla Pouckova, Martina Kabesova, Jiri Benes, Tomas Olejar, Jan Bouček, David Vetvicka

Publikováno v: Anticancer Research. 40:349-356

BACKGROUND/AIM Follicle-stimulating hormone receptor (FSHr), expressed on endothelial cells of vessels in different malignant tumors, has been recently investigated as a potential pan-receptor of cancer treatment. However, the expression of this rece

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e73b14453be70c39ba0cd50b21827c
https://doi.org/10.21873/anticanres.13959

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Extracellular Protein Aggregates Colocalization and Neuronal Dystrophy in Comorbid Alzheimer’s and Creutzfeldt–Jakob Disease: A Micromorphological Pilot Study on 20 Brains

Autor: Tomas Olejar, Radoslav Matej, Nikol Jankovska

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 2099, p 2099 (2021)

Alzheimer’s disease (AD) and sporadic Creutzfeldt–Jakob disease (sCJD) are both characterized by extracellular pathologically conformed aggregates of amyloid proteins—amyloid β-protein (Aβ) and prion protein (PrPSc), respectively. To investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414083bfa4bde3ff20cbcada7d6c4da3
http://europepmc.org/articles/PMC7924045

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