Zobrazeno 1 - 10
of 446
pro vyhledávání: '"Tomas, Hudlicky"'
Publikováno v:
Molecules, Vol 27, Iss 12, p 3809 (2022)
A 15-step chemoenzymatic total synthesis of C-1 methoxycarbonyl narciclasine (10) was accomplished. The synthesis began with the toluene dioxygenase-mediated dihydroxylation of ortho-dibromobenzene to provide the corresponding cis-dihydrodiol (12) as
Externí odkaz:
https://doaj.org/article/94d46c11a84b4e0f86f9436b8ec3c162
Autor:
Juana Goulart Stollmaier, Jared Thomson, Mary Ann Endoma-Arias, Razvan Simionescu, Alexandra Vernaza, Nakya Mesa-Diaz, Mitchell Smith, Liqin Du, Alexander Kornienko, Tomas Hudlicky
Publikováno v:
Molecules, Vol 27, Iss 13, p 4141 (2022)
During the search for a general, efficient route toward the synthesis of C-1 analogues of narciclasine, natural narciclasine was protected and converted to its C-1 enol derivative using a novel semi-synthetic route. Attempted conversion of this mater
Externí odkaz:
https://doaj.org/article/9f9c0ee435974faa96ff85226fb24787
Autor:
Tomas Hudlicky
Publikováno v:
ACS Omega, Vol 3, Iss 12, Pp 17326-17340 (2018)
Externí odkaz:
https://doaj.org/article/89a38b4f75c4465eae4ea4ee65c610c5
Publikováno v:
Molecules, Vol 24, Iss 19, p 3477 (2019)
The total synthesis of (+)-10-keto-oxycodone was attained from phenethyl acetate in a stereoselective manner. Absolute stereochemistry was established via enzymatic dihydroxylation of phenethyl acetate with the recombinant strain JM109 (pDTG601A) tha
Externí odkaz:
https://doaj.org/article/6c086a937fbf4043bd26600448eb7116
Publikováno v:
ChemistrySelect. 5:8241-8245
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bb1282960bc669f07a6df405a530f5c
https://doi.org/10.1002/slct.202001320
https://doi.org/10.1002/slct.202001320
Publikováno v:
Tetrahedron
A chemoenzymatic convergent synthesis of 10-benzyloxy narciclasine from bromobenzene was accomplished in 16 steps. The key transformations included toluene dioxygenase-mediated hydroxylation, nitroso Diels-Alder reaction and intramolecular Heck cycli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1630ba8be5d69e0b90b10af928490260
https://europepmc.org/articles/PMC8765737/
https://europepmc.org/articles/PMC8765737/
Publikováno v:
The Alkaloids. Chemistry and biology. 86
This chapter provides a short overview of the history of morphine since it's isolation by Sertürner in 1805. The biosynthesis of the title alkaloid as well as all total and formal syntheses of morphine and codeine published after 1996 are discussed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3dab764a46fcbf4f9e87e3e3b0e514eb
https://pubmed.ncbi.nlm.nih.gov/34565506
https://pubmed.ncbi.nlm.nih.gov/34565506
Autor:
Tomas Hudlicky
Publikováno v:
ARKIVOC, Vol 2006, Iss 7, Pp 276-291 (2006)
Externí odkaz:
https://doaj.org/article/c9f01d23c1064436bec36dabd592cc93
Publikováno v:
European Journal of Organic Chemistry. 2019:7590-7595
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13f983b6fa4f5ef7b475c2104a5c39e8
https://doi.org/10.1002/ejoc.201901549
https://doi.org/10.1002/ejoc.201901549
Publikováno v:
Angewandte Chemie. 131:18506-18558
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc69ad10fb813476777005fdb28a385c
https://doi.org/10.1002/ange.201901564
https://doi.org/10.1002/ange.201901564