Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Tomas, Eckschlager"'
Autor:
Miguel Angel Merlos Rodrigo, Hana Michalkova, Vladislav Strmiska, Berta Casar, Piero Crespo, Vivian de los Rios, J. Ignacio Casal, Yazan Haddad, Roman Guran, Tomas Eckschlager, Petra Pokorna, Zbynek Heger, Vojtech Adam
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Metallothionein-3 has poorly characterized functions in neuroblastoma. Cisplatin-based chemotherapy is a major regimen to treat neuroblastoma, but its clinical efficacy is limited by chemoresistance. We investigated the impact of human metal
Externí odkaz:
https://doaj.org/article/c380e720965d4d49b73aadef566e6723
Autor:
Katerina Kopeckova, Tomas Eckschlager, Jakub Sirc, Radka Hobzova, Johana Plch, Jan Hrabeta, Jiri Michalek
Publikováno v:
Biomedical Papers, Vol 163, Iss 2, Pp 122-131 (2019)
Cancer despite the introduction of new targeted therapy remains for many patients a fatal disease. Nanotechnology in cancer medicine has emerged as a promising approach to defeat cancer. Targeted delivery of anti-cancer drugs by different nanosystems
Externí odkaz:
https://doaj.org/article/12a95c3a29c2432da570dc4f529a1450
Autor:
Vladislav Strmiska, Petr Michalek, Zuzana Lackova, Roman Guran, Sona Krizkova, Lucie Vanickova, Ondrej Zitka, Marie Stiborova, Tomas Eckschlager, Borivoj Klejdus, Dalibor Pacik, Eliska Tvrdikova, Claudia Keil, Hajo Haase, Vojtech Adam, Zbynek Heger
Publikováno v:
Molecular Oncology, Vol 13, Iss 5, Pp 1002-1017 (2019)
DNA hypermethylation is one of the most common epigenetic modifications in prostate cancer (PCa). Several studies have delineated sarcosine as a PCa oncometabolite that increases the migration of malignant prostate cells while decreasing their doubli
Externí odkaz:
https://doaj.org/article/04f0e5a202ed485ea5b906c03279d789
Autor:
Jarmila Kruseova, Anna Sarah Kovacova, Michal Zapotocky, David Sumerauer, Ivana Pernikova, Darja Starkova, Adela Misove, Andrea Zichova, Vaclav Capek, Thorsten Langer, Antoinette Am Zehnhoff-Dinnesen, Tomas Eckschlager, Martin Kyncl
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243998 (2020)
The treatment of children with posterior fossa brain tumours (PFBT) impacts their long term functional and imaging outcomes. This study aimed to evaluate academic achievement correlated with long-term sequelae after different PFBT treatment modalitie
Externí odkaz:
https://doaj.org/article/510f59a9d5a949bcb5fe4098c2d6f23e
Publikováno v:
Biomedical Papers, Vol 159, Iss 2, Pp 166-177 (2015)
Background: The aim of this review is to provide the information about molecular basis of hypoxia-induced chemoresistance, focusing on the possibility of diagnostic and therapeutic use. Results: Hypoxia is a common feature of tumors and represents an
Externí odkaz:
https://doaj.org/article/9753e35b8886484eb8453acea3e74463
Publikováno v:
Oncology Letters. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc5a3169d6e82255750404826fe7f47d
https://doi.org/10.3892/ol.2022.13629
https://doi.org/10.3892/ol.2022.13629
Autor:
Jarmila Kruseova, Ales Luks, Barbora Gottfriedová, Karel Svojgr, Petr Hosek, Martin Kyncl, Tomas Eckschlager, Andrea Zichová
Publikováno v:
Clinical Epidemiology
Jarmila Kruseová,1 Barbora Gottfriedová,2 Andrea Zichová,1 Karel Å vojgr,1 Petr HoÅ¡ek,3 AleÅ¡ LukÅ¡,1 Martin Kynčl,2 Tomáš Eckschlager1 1Department of Paediatric Haematology and Oncology, 2nd Faculty of Medicine, Charles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59ee7665806e1a3a8f8e103d41c709a
https://doi.org/10.2147/clep.s317903
https://doi.org/10.2147/clep.s317903
Autor:
Martina Raudenska, Ludmila Krejcova, Lukas Richtera, Zbynek Heger, Jan Hrabeta, Tomas Eckschlager, Marie Stiborova, Vojtech Adam, Monika Kratochvilova, Michal Masarik, Jaromir Gumulec
Publikováno v:
Tumor Biology, Vol 39 (2017)
Neuroblastoma represents a malignancy of the sympathetic nervous system characteristic by biological heterogeneity. Thus, chemotherapy exhibits only low effectivity in curing high-risk forms. Previous studies revealed the cytotoxic potential of valpr
Externí odkaz:
https://doaj.org/article/b0971fb99a644becbfca7f7df620ebb9
Publikováno v:
Oncol Lett
Chemoresistance is a major problem in successful cancer therapy. Lysine-specific demethylase 5B (KDM5B), is a member of the KDM5 family of histone demethylases, whose dysregulation has been observed in numerous types of cancer and plays a role in dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9bcb21ef8fe0db815e44ef4728c556d
https://europepmc.org/articles/PMC9494299/
https://europepmc.org/articles/PMC9494299/
Autor:
Zbynek Heger, Miguel Angel Merlos Rodrigo, Petr Michalek, Hana Polanska, Michal Masarik, Vitezslav Vit, Mariana Plevova, Dalibor Pacik, Tomas Eckschlager, Marie Stiborova, Vojtech Adam
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165830 (2016)
The effects of sarcosine on the processes driving prostate cancer (PCa) development remain still unclear. Herein, we show that a supplementation of metastatic PCa cells (androgen independent PC-3 and androgen dependent LNCaP) with sarcosine stimulate
Externí odkaz:
https://doaj.org/article/e0dd4ea7f85c43e08a03d6591ff42422