Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Tomas, Drgon"'
Publikováno v:
Annals of Biomedical Engineering. 51:6-9
Autor:
Chun-Ting Lee, Raphael M. Bendriem, Abigail A. Kindberg, Lila T. Worden, Melanie P. Williams, Tomas Drgon, Barbara S. Mallon, Brandon K. Harvey, Christopher T. Richie, Rebecca S. Hamilton, Jia Chen, Stacie L. Errico, Shang-Yi A. Tsai, George R. Uhl, William J. Freed
Publikováno v:
Cell Reports, Vol 10, Iss 4, Pp 616-632 (2015)
Human pluripotent stem cell (hPSC) lines exhibit repeated patterns of genetic variation, which can alter in vitro properties as well as suitability for clinical use. We examined associations between copy-number variations (CNVs) on chromosome 17 and
Externí odkaz:
https://doaj.org/article/270a8a7e6811439e9276a9c0231e0f07
Publikováno v:
Annals of biomedical engineering.
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e19210 (2011)
Declaring "replication" from results of genome wide association (GWA) studies is straightforward when major gene effects provide genome-wide significance for association of the same allele of the same SNP in each of multiple independent samples. Howe
Externí odkaz:
https://doaj.org/article/d1b443d5191e46acb736b423166ff5e9
Autor:
Tomas Drgon, Ping-Wu Zhang, Catherine Johnson, Donna Walther, Judith Hess, Michelle Nino, George R Uhl
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8832 (2010)
BackgroundVulnerabilities to dependence on addictive substances are substantially heritable complex disorders whose underlying genetic architecture is likely to be polygenic, with modest contributions from variants in many individual genes. "Nontempl
Externí odkaz:
https://doaj.org/article/ebe9c07740c54510988fa43695fa6a07
Autor:
Rebecca S. Hamilton, Raphael M. Bendriem, Stacie L. Errico, Tomas Drgon, Jia Chen, Chun Ting Lee, Barbara S. Mallon, Abigail A. Kindberg, Shang-Yi Tsai, George R. Uhl, Melanie P. Williams, William J. Freed, Brandon K. Harvey, Christopher T. Richie, Lila T. Worden
Publikováno v:
Cell Reports, Vol 10, Iss 4, Pp 616-632 (2015)
SummaryHuman pluripotent stem cell (hPSC) lines exhibit repeated patterns of genetic variation, which can alter in vitro properties as well as suitability for clinical use. We examined associations between copy-number variations (CNVs) on chromosome
Autor:
Tomas Drgon, Kuppuswamy N. Kasturi
Publikováno v:
Applied and Environmental Microbiology. 83
The methods currently used for detecting Salmonella in environmental samples require 2 days to produce results and have limited sensitivity. Here, we describe the development and validation of a real-time PCR Salmonella screening method that produces
Autor:
George R. Uhl, Paul Aveyard, Michael F. Murphy, Tomas Drgon, Marcus R. Munafò, Sean P. David, Donna Walther, Elaine C. Johnstone, Catherine Johnson
Aims: To confirm and extend to primary care settings prior genome-wide association results that distinguish smokers who successfully quit from individuals who were not able to quit smoking in clinical trials. Materials & methods: Affymetrix® 6.0 Arr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23866a3bbced7f7560c168fab7255cbc
https://doi.org/10.2217/pgs.09.156
https://doi.org/10.2217/pgs.09.156
Autor:
Marco F. Ramoni, George R. Uhl, Jed E. Rose, Tomas Drgon, Frederique M. Behm, Catherine Johnson
Publikováno v:
Molecular Medicine. 16:513-526
Abilities to successfully quit smoking display substantial evidence for heritability in classic and molecular genetic studies. Genome-wide association (GWA) studies have demonstrated single-nucleotide polymorphisms (SNPs) and haplotypes that distingu
Publikováno v:
Molecular Medicine. 15:268-274
The ability to quit smoking successfully displays substantial heritability in classical and molecular genetic studies. Twin studies suggest that some of the genetics for the ability to quit overlap with genetic components of nicotine dependence, but