Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Tomas, Buchler"'
Autor:
Martina Borcinova, Robin Bartolini, Lily Koumbas Foley, Vojtech Novak, Pavla Taborska, Dmitry Stakheev, Michal Rataj, Daniel Smrz, Martina Fialova, Jaromir Hacek, Martin Komarc, Stepan Vesely, Marek Babjuk, Ilja Striz, Jirina Bartunkova, Tomas Buchler, Zuzana Ozaniak Strizova
Publikováno v:
Translational Oncology, Vol 42, Iss , Pp 101891- (2024)
Renal cell carcinoma (RCC) is a common malignancy frequently diagnosed at the metastatic stage. We performed a comprehensive analysis of the tumor immune microenvironment (TIME) in RCC patients, including the peritumoral tissue microenvironment, to c
Externí odkaz:
https://doaj.org/article/b45ce9ed86cf4aa798f89ac36853a827
Autor:
Viktor Grünwald, Thomas Powles, Masatoshi Eto, Evgeny Kopyltsov, Sun Young Rha, Camillo Porta, Robert Motzer, Thomas E. Hutson, María José Méndez-Vidal, Sung-Hoo Hong, Eric Winquist, Jeffrey C. Goh, Pablo Maroto, Tomas Buchler, Toshio Takagi, Joseph E. Burgents, Rodolfo Perini, Cixin He, Chinyere E. Okpara, Jodi McKenzie, Toni K. Choueiri
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
Externí odkaz:
https://doaj.org/article/3d4ee96893544a25bb56c9e784f1f819
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/5bc119eab61947b4917dfff1dfd3a809
Autor:
Viktor Grünwald, Thomas Powles, Masatoshi Eto, Evgeny Kopyltsov, Sun Young Rha, Camillo Porta, Robert Motzer, Thomas E. Hutson, María José Méndez-Vidal, Sung-Hoo Hong, Eric Winquist, Jeffrey C. Goh, Pablo Maroto, Tomas Buchler, Toshio Takagi, Joseph E. Burgents, Rodolfo Perini, Cixin He, Chinyere E. Okpara, Jodi McKenzie, Toni K. Choueiri
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionThe phase 3 CLEAR study demonstrated that lenvatinib plus pembrolizumab significantly improved efficacy versus sunitinib as first-line treatment for patients with advanced renal cell carcinoma (RCC). Prognostic features including presence
Externí odkaz:
https://doaj.org/article/09be4e69130a41858b234cdb2b5887cc
Autor:
Otakar Semerad, Tomas Buchler, Jiri Vejmelka, Aneta Rozsypalova, Jitka Tomesova, Pavel Kohout
Publikováno v:
Biomedical Papers, Vol 166, Iss 1, Pp 91-96 (2022)
Background. Testicular cancer is associated with excellent prognosis and cure is achieved in most patients with advanced cancer treated with cisplatin-based chemotherapy. However, testicular cancer survivors are at increased risk of accelerated ather
Externí odkaz:
https://doaj.org/article/6e94ca63d14e486ea9e8993755fb1ec6
Autor:
Igor Richter, Alexandr Poprach, Anezka Zemankova, Tomas Buchler, Jiri Bartos, Vladimir Samal, Hana Studentova, Aneta Rozsypalova, Josef Dvorak, Ondrej Brom, Bohuslav Melichar
Publikováno v:
Biomedical Papers, Vol 166, Iss 1, Pp 97-104 (2022)
Aim. The aim of this study was to retrospectively analyze treatment outcomes and tolerance in patients in whom cabozantinib was used after previous targeted therapy. Patients and Methods. Cabozantinib was administered in dose 60 mg/day, a subset of p
Externí odkaz:
https://doaj.org/article/15cacfbb56434393aa47bcaf504f7acd
Publikováno v:
Current Oncology, Vol 28, Iss 5, Pp 3403-3407 (2021)
Spontaneous regression of metastatic renal cell carcinoma (mRCC) is a rare event, often associated with an activation of innate immunity by various triggers. SARS-CoV-2 infection induces a strong inflammatory response in some patients and a cytokine
Externí odkaz:
https://doaj.org/article/52ce574459ed451ba7cff1f616e7ba1e
Autor:
Michal Kroupa, Kristyna Tomasova, Miriam Kavec, Pavel Skrobanek, Tomas Buchler, Rajiv Kumar, Ludmila Vodickova, Pavel Vodicka
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Telomeres are complex protective structures located at the ends of linear eukaryotic chromosomes. Their purpose is to prevent genomic instability. Research progress in telomere biology during the past decades has identified a network of telomeric tra
Externí odkaz:
https://doaj.org/article/62b41bcb715b4e7fbf4ee3be041aeaf4
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
PurposeInsomnia in cancer patients is a common symptom contributing to poor quality of life and poor functioning. Sleep disturbances have been associated with inflammatory activity, and systemic cancer therapies chemotherapy, hormonal therapy, and im
Externí odkaz:
https://doaj.org/article/48b2a61741d14628871924795ce4ad52
Autor:
Tomas Buchler
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Approximately 4-5% of patients with metastatic colorectal cancer (mCRC) have mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) tumours. These tumours present challenges in the clinical practice due to variant response to fluoro
Externí odkaz:
https://doaj.org/article/bd9265968986465884640ff6714f54fd