Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tomaž Büdefeld"'
Autor:
Matthew S Stratton, Michelle Staros, Tomaz Budefeld, Brian T Searcy, Connor Nash, Chad Eitel, David Carbone, Robert J Handa, Gregor Majdic, Stuart A Tobet
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e106015 (2014)
Neurons of the paraventricular nucleus of the hypothalamus (PVN) regulate the hypothalamic- pituitary-adrenal (HPA) axis and the autonomic nervous system. Females lacking functional GABA(B) receptors because of a genetic disruption of the R1 subunit
Externí odkaz:
https://doaj.org/article/bad640f52130422aac37d9f8199260fc
Autor:
Larisa Goričan, Tomaž Büdefeld, Helena Čelešnik, Matija Švagan, Boštjan Lanišnik, Uroš Potočnik
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 6, Pp 4632-4646 (2023)
Epigenetic studies on the role of DNA-modifying enzymes in HNSCC tumorigenesis have focused on a single enzyme or a group of enzymes. To acquire a more comprehensive insight into the expression profile of methyltransferases and demethylases, in the p
Externí odkaz:
https://doaj.org/article/1fcb549ecc914b4db9f2893be45dc050
Autor:
Živa Ledinek, Monika Sobočan, Damjan Sisinger, Marko Hojnik, Tomaž Büdefeld, Uroš Potočnik, Jure Knez
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Endometrial cancer is the most common gynecologic malignancy in the developed world. Risk stratification and treatment approaches are changing due to better understanding of tumor biology. Upregulated Wnt signaling plays an important role in cancer i
Externí odkaz:
https://doaj.org/article/fa60fda95c914cfab0366d15d6bab815
Autor:
Jakob Kljun, Renata Pavlič, Eva Hafner, Tanja Lipec, Sara Moreno-Da Silva, Primož Tič, Iztok Turel, Tomaž Büdefeld, Jure Stojan, Tea Lanišnik Rižner
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
In this study, we present the synthesis, kinetic studies of inhibitory activity toward aldo-keto reductase 1C (AKR1C) enzymes, and anticancer potential toward chemoresistant ovarian cancer of 10 organoruthenium compounds bearing diketonate (1–6) an
Externí odkaz:
https://doaj.org/article/f20c38b2a3054eb28ff3e7533d899f2f
Autor:
Maša Sinreih, Rebeka Jójárt, Zoltán Kele, Tomaž Büdefeld, Gábor Paragi, Erzsébet Mernyák, Tea Lanišnik Rižner
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1499-1507 (2021)
Enzymes AKR1C regulate the action of oestrogens, androgens, and progesterone at the pre-receptor level and are also associated with chemo-resistance. The activities of these oestrone halides were investigated on recombinant AKR1C enzymes. The oestron
Externí odkaz:
https://doaj.org/article/85552082a3ce4fee999b489015b2a35d
Autor:
Renata Pavlič, Suzana Vidic, Maja Anko, Tamara Knific, Tomaž Büdefeld, Kristina Marton, Maša Sinreih, Stefan Poschner, Walter Jäger, Snježana Frković-Grazio, Tea Lanišnik Rižner
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 3819 (2021)
Endometrial cancer (EC) is associated with increased estrogen actions. Locally, estrogens can be formed from estrone-sulphate (E1-S) after cellular uptake by organic anion-transporting polypeptides (OATP) or organic anion transporters (OAT). Efflux o
Externí odkaz:
https://doaj.org/article/2a297a4741604ca5a2beb4738fff4867
Publikováno v:
Cancers; Volume 14; Issue 19; Pages: 4681
Background: Acute myeloid leukemia (AML) and chronic myeloid leukemia (CML) represent a group of hematological malignancies characterized by the pathogenic clonal expansion of leukemic myeloid cells. The diagnosis and clinical outcome of AML and CML
Autor:
Tomaž Büdefeld, Maša Sinreih, Zoltán Kele, Rebeka Jójárt, Gábor Paragi, Erzsébet Mernyák, Tea Lanišnik Rižner
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of enzyme inhibition and medicinal chemistry, vol. 36, no. 1, 2021.
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1499-1507 (2021)
article-version (VoR) Version of Record
Journal of enzyme inhibition and medicinal chemistry, vol. 36, no. 1, 2021.
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1499-1507 (2021)
Enzymes AKR1C regulate the action of oestrogens, androgens, and progesterone at the pre-receptor level and are also associated with chemo-resistance. The activities of these oestrone halides were investigated on recombinant AKR1C enzymes. The oestron
Autor:
Tea Lanišnik Rižner, Tomaž Büdefeld, Snježana Frković-Grazio, Walter Jäger, Renata Pavlič, Tamara Knific, Maša Sinreih, Maja Anko, Suzana Vidic, Kristina Marton, Stefan Poschner
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 3819, p 3819 (2021)
Volume 22
Issue 8
International Journal of Molecular Sciences, Vol 22, Iss 3819, p 3819 (2021)
Volume 22
Issue 8
Endometrial cancer (EC) is associated with increased estrogen actions. Locally, estrogens can be formed from estrone-sulphate (E1-S) after cellular uptake by organic anion-transporting polypeptides (OATP) or organic anion transporters (OAT). Efflux o
Publikováno v:
Journal of oral pathologymedicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral PathologyREFERENCES. 50(9)
BACKGROUND Head and neck cancer (HNSCC) is one of the most lethal cancers characterized by high relapse and poor prognosis. Several miRNAs have been implicated in HNSCC, including the tumor suppressor miR-137. A large CpG island (CpG73) spans most of