Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Tom Truong"'
Autor:
Navid Nouri, Bailey Hannon Gussler, Amy Stockwell, Tom Truong, Gyeong Jin Kang, Kristen C. Browder, Yann Malato, Abdoulaye Sene, Sherri Van Everen, Charles C. Wykoff, David Brown, Arthur Fu, James D. Palmer, Jose Ronaldo Lima de Carvalho, Ehsan Ullah, Ranya Al Rawi, Emily Y. Chew, Wadih M. Zein, Bin Guan, Mark I. McCarthy, Jeffrey W. Hofmann, Shawnta Y. Chaney, Heinrich Jasper, Brian L. Yaspan
Publikováno v:
npj Genomic Medicine, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Age-related macular degeneration (AMD), a complex neurodegenerative disease, is a leading cause of visual impairment worldwide with a strong genetic component. Genetic studies have identified several loci, but few causal genes with functiona
Externí odkaz:
https://doaj.org/article/ab0df09aee6145bab141375377878984
Autor:
Melissa K. Jones, Luz D. Orozco, Han Qin, Tom Truong, Patrick Caplazi, Justin Elstrott, Zora Modrusan, Shawnta Y. Chaney, Marion Jeanne
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Rare DRAM2 coding variants cause retinal dystrophy with early macular involvement via unknown mechanisms. We found that DRAM2 is ubiquitously expressed in the human eye and expression changes were observed in eyes with more common maculopathy such as
Externí odkaz:
https://doaj.org/article/4d5ae22863834591822d2aa0e0991e50
Autor:
Martin Weber, Sang-Won Min, Tom Truong, Jeffrey Hung, Stephanie Dale, Mike Reichelt, Savita Ubhayakar, Carol Cain-Hom, Miriam Baca, Zhiyu Jiang, Qingling Li, Robert Brendza, Han Lin, Chung Kung, William F. Forrest, Cristine Quiason-Huynh, Wendy Sandoval, Buyun Chen, Yuzhong Deng, Amy Easton, Oded Foreman, Abdoulaye Sene, Baris Bingol
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Mutations in the GBA1 gene encoding glucocerebrosidase (GCase) are linked to Gaucher (GD) and Parkinson’s Disease (PD). Since some GD and PD patients develop ocular phenotypes, we determined whether ocular phenotypes might result from impa
Externí odkaz:
https://doaj.org/article/08dc67cbf02f4f9ab4c713dcac4d0867
Autor:
Klaus P. Hoeflich, Mark X. Sliwkowski, Lori S. Friedman, Lesley J. Murray, Marcia Belvin, Bert Gunter, Nicholas Lewin-Koh, Jeffrey Eastham-Anderson, Peter M. Haverty, Tom Truong, Si Tuen Lee-Hoeflich, Wei Zhou, Evelyn Yao
Purpose: Oncogenic activation of the phosphatidylinositol 3-kinase (PI3K) signaling pathway is prevalent in breast cancer and has been associated with resistance to HER2 inhibitors in the clinic. We therefore investigated the combinatorial activity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47fd590db93aa99ce95ad46b18daa8e8
https://doi.org/10.1158/1078-0432.c.6517759.v1
https://doi.org/10.1158/1078-0432.c.6517759.v1
Autor:
Mark R. Lackner, Lori S. Friedman, Marcia Belvin, Lukas Amler, Lesley Murray, Leanne Berry, Wei Zhou, Tom Truong, Elizabeth Punnoose, Heidi Savage, Tom Januario, Kenneth Jung, Steve Guerrero, Guy Cavet, Zachary Boyd, Carol O'Brien, Klaus P. Hoeflich
Purpose: The pathways underlying basal-like breast cancer are poorly understood, and as yet, there is no approved targeted therapy for this disease. We investigated the role of mitogen-activated protein kinase kinase (MEK) and phosphatidylinositol 3-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b168ddd5fe9feef9198511f1a99af2
https://doi.org/10.1158/1078-0432.c.6517446.v1
https://doi.org/10.1158/1078-0432.c.6517446.v1
Autor:
Mark R. Lackner, Lori S. Friedman, Marcia Belvin, Lukas Amler, Lesley Murray, Leanne Berry, Wei Zhou, Tom Truong, Elizabeth Punnoose, Heidi Savage, Tom Januario, Kenneth Jung, Steve Guerrero, Guy Cavet, Zachary Boyd, Carol O'Brien, Klaus P. Hoeflich
Supplementary Data from In vivo Antitumor Activity of MEK and Phosphatidylinositol 3-Kinase Inhibitors in Basal-Like Breast Cancer Models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88dbb088331655cbbdf912262e9aeb6c
https://doi.org/10.1158/1078-0432.22440072.v1
https://doi.org/10.1158/1078-0432.22440072.v1
Autor:
Klaus P. Hoeflich, Mark X. Sliwkowski, Lori S. Friedman, Lesley J. Murray, Marcia Belvin, Bert Gunter, Nicholas Lewin-Koh, Jeffrey Eastham-Anderson, Peter M. Haverty, Tom Truong, Si Tuen Lee-Hoeflich, Wei Zhou, Evelyn Yao
Supplementary Data from Suppression of HER2/HER3-Mediated Growth of Breast Cancer Cells with Combinations of GDC-0941 PI3K Inhibitor, Trastuzumab, and Pertuzumab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8806fd4fdefebede873da4612013d796
https://doi.org/10.1158/1078-0432.22440430.v1
https://doi.org/10.1158/1078-0432.22440430.v1
Autor:
Ron Firestein, Jiping Zha, Marie Evangelista, Laura Corson, Elizabeth M. Blackwood, Georgia Hatzivassiliou, Marcia Belvin, Jean-Philippe Stephan, Benjamin Haley, Li Li, Eric Torres, David Peterson, Tom Truong, Thomas Hunsaker, Yonglei Shang, Adam S. Adler, Mark L. McCleland
PDF file - 95K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::480c1992d905cab65f4b0f74e79ecc0e
https://doi.org/10.1158/0008-5472.22394598
https://doi.org/10.1158/0008-5472.22394598
Autor:
Ron Firestein, Jiping Zha, Marie Evangelista, Laura Corson, Elizabeth M. Blackwood, Georgia Hatzivassiliou, Marcia Belvin, Jean-Philippe Stephan, Benjamin Haley, Li Li, Eric Torres, David Peterson, Tom Truong, Thomas Hunsaker, Yonglei Shang, Adam S. Adler, Mark L. McCleland
PDF file - 6626K, Validation of IHC antibody specificity for LDHB, LDHA, MCT1, and MCT4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22600026dbf51a00a8c1f8e317f11ecf
https://doi.org/10.1158/0008-5472.22394601.v1
https://doi.org/10.1158/0008-5472.22394601.v1
Autor:
Ron Firestein, Jiping Zha, Marie Evangelista, Laura Corson, Elizabeth M. Blackwood, Georgia Hatzivassiliou, Marcia Belvin, Jean-Philippe Stephan, Benjamin Haley, Li Li, Eric Torres, David Peterson, Tom Truong, Thomas Hunsaker, Yonglei Shang, Adam S. Adler, Mark L. McCleland
PDF file - 963K, Additional top targets from RNAi screen that are specifically required for triple negative breast cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00756adb9f6aaf384f338f6a1ad6df9a
https://doi.org/10.1158/0008-5472.22394616.v1
https://doi.org/10.1158/0008-5472.22394616.v1