Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Tom Schilling"'
Autor:
Michael J. D. Daniels, Jack Rivers-Auty, Tom Schilling, Nicholas G. Spencer, William Watremez, Victoria Fasolino, Sophie J. Booth, Claire S. White, Alex G. Baldwin, Sally Freeman, Raymond Wong, Clare Latta, Shi Yu, Joshua Jackson, Nicolas Fischer, Violette Koziel, Thierry Pillot, James Bagnall, Stuart M. Allan, Pawel Paszek, James Galea, Michael K. Harte, Claudia Eder, Catherine B. Lawrence, David Brough
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
NSAID-induced analgesia is typically induced by inhibition of COX enzymes. Here the authors show instead that fenamate NSAIDs inhibit the Nlrp3 inflammasome via an effect on volume-regulated anion channel function and also repurpose these drugs for t
Externí odkaz:
https://doaj.org/article/dca8360eb57c4ee588985f6c192c8a0c
Mechanisms Underlying Interferon-γ-Induced Priming of Microglial Reactive Oxygen Species Production.
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162497 (2016)
Microglial priming and enhanced reactivity to secondary insults cause substantial neuronal damage and are hallmarks of brain aging, traumatic brain injury and neurodegenerative diseases. It is, thus, of particular interest to identify mechanisms invo
Externí odkaz:
https://doaj.org/article/359418bb6bb4496cb836372666c7472c
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128463 (2015)
Brain tissue damage following stroke or traumatic brain injury is accompanied by neuroinflammatory processes, while microglia play a central role in causing and regulating neuroinflammation via production of proinflammatory substances, including cyto
Externí odkaz:
https://doaj.org/article/220babd36e5146aea66b3737bf392be1
This publication presents the results of the fundamental research on the interaction of laser radiation and lignocellulosic fibres with respect to the melting of the fibre main components cellulose, hemicellulose and lignin. In the first part, hand s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7fc35bcd57d9def7ad3c2a461b0316
https://publica.fraunhofer.de/handle/publica/419202
https://publica.fraunhofer.de/handle/publica/419202
Publikováno v:
Laser-based Micro- and Nanoprocessing XV.
This paper presents the results of fundamental studies on the interaction of laser radiation with classical paper materials regarding the melting of the main paper components cellulose, hemicellulose and lignin. Different papers were irradiated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6cfef6e9c062f8551bcae01e96448f2
https://doi.org/10.1117/12.2577097
https://doi.org/10.1117/12.2577097
Autor:
Tom Schilling, Claudia Eder
Publikováno v:
Glia
The K(+) channel expression pattern of microglia strongly depends on the cells' microenvironment and has been recognized as a sensitive marker of the cells' functional state. While numerous studies have been performed on microglia in vitro, our knowl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d81b5c82b55e2696dfcfaf08f621b8
https://doi.org/10.1002/glia.22776
https://doi.org/10.1002/glia.22776
Autor:
Tom Schilling, Claudia Eder
Publikováno v:
Cellular Immunology. 265:87-90
Lipid rafts play an important role in regulating cellular processes and functions. Here, we demonstrate that in microglia stimulated with the pro-inflammatory lipid lysophosphatidylcholine (LPC), caspase-1 activation and NADPH oxidase activity depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b284c5df4165df0e4e0ab8ac361dd9d6
https://doi.org/10.1016/j.cellimm.2010.08.003
https://doi.org/10.1016/j.cellimm.2010.08.003
Autor:
Claudia Eder, Tom Schilling
Publikováno v:
Journal of Neuroimmunology. 216:118-121
Activated microglial cells generate reactive oxygen species (ROS), which have detrimental effects in neuroinflammatory and neurodegenerative diseases. In the present study, we have identified a novel mechanism involved in microglial NADPH oxidase-med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453d20279607ec54059774d027b913df
https://doi.org/10.1016/j.jneuroim.2009.07.008
https://doi.org/10.1016/j.jneuroim.2009.07.008
Autor:
Claudia Eder, Tom Schilling
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 454:559-563
TRAM-34 has been demonstrated to inhibit intermediate-conductance Ca(2+)-activated K(+) channels in a wide variety of cell types, including immune cells. In the present study, we investigated effects of TRAM-34 on microglial cells stimulated with lys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68dc775ec03edd6c03b5b617252dacff
https://doi.org/10.1007/s00424-007-0232-4
https://doi.org/10.1007/s00424-007-0232-4
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128463 (2015)
PLoS ONE
PLoS ONE
Brain tissue damage following stroke or traumatic brain injury is accompanied by neuroinflammatory processes, while microglia play a central role in causing and regulating neuroinflammation via production of proinflammatory substances, including cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f97b135922483c31159303f26fc88cb
http://europepmc.org/articles/PMC4444306?pdf=render
http://europepmc.org/articles/PMC4444306?pdf=render