Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Tom S. Weber"'
Autor:
Tom S. Weber
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Adaptation of antibody-mediated immunity occurs in germinal centers (GC). It is where affinity maturation, class switching, memory and plasma cell differentiation synergize to generate specific high-affinity antibodies that aid both to clear and prot
Externí odkaz:
https://doaj.org/article/ea2bf97ce4be46fb89f7bb9fcf01e025
Autor:
Tom S. Weber, Christine Biben, Denise C. Miles, Stefan Glaser, Sara Tomei, Stephen Zhang, Patrick P. L. Tam, Samir Taoudi, Shalin H. Naik
Contribution of the mammalian epiblast to fetal organs during embryogenesis has been investigated using reporters of marker genes, or through single cell or spatial RNA sequencing to infer differentiation trajectories. However, much remains to be lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1db86fc92d1177c437df38e49b42f47a
https://doi.org/10.1101/2023.01.02.522501
https://doi.org/10.1101/2023.01.02.522501
Autor:
Katie A. Fennell, Dane Vassiliadis, Enid Y. N. Lam, Luciano G. Martelotto, Jesse J. Balic, Sebastian Hollizeck, Tom S. Weber, Timothy Semple, Qing Wang, Denise C. Miles, Laura MacPherson, Yih-Chih Chan, Andrew A. Guirguis, Lev M. Kats, Emily S. Wong, Sarah-Jane Dawson, Shalin H. Naik, Mark A. Dawson
Publikováno v:
Nature. 601:125-131
Autor:
Kaspar Bresser, Lianne Kok, Arpit C. Swain, Lisa A. King, Laura Jacobs, Tom S. Weber, Leïla Perié, Ken R. Duffy, Rob J. de Boer, Ferenc A. Scheeren, Ton N. Schumacher
Publikováno v:
Nature Immunology. 23:1132-1132
Autor:
Kaspar Bresser, King L, Swain A, Leïla Perié, Kok L, Scheeren F, Tom S. Weber, Ton N. Schumacher, Ken R. Duffy, Jacobs L, Boer Rd
Clonal expansion is a core aspect of T cell immunity. However, little is known with respect to the relationship between replicative history and the formation of distinct CD8+ memory T cell subgroups. To address this issue, we developed a genetic-trac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4d10cbba662bad22cfd7d707989fd6f
https://doi.org/10.21203/rs.3.rs-310238/v1
https://doi.org/10.21203/rs.3.rs-310238/v1
Autor:
Kaspar, Bresser, Lianne, Kok, Arpit C, Swain, Lisa A, King, Laura, Jacobs, Tom S, Weber, Leïla, Perié, Ken R, Duffy, Rob J, de Boer, Ferenc A, Scheeren, Ton N, Schumacher
Publikováno v:
Nature immunology. 23(5)
Clonal expansion is a core aspect of T cell immunity. However, little is known with respect to the relationship between replicative history and the formation of distinct CD8
Autor:
Katie A, Fennell, Dane, Vassiliadis, Enid Y N, Lam, Luciano G, Martelotto, Jesse J, Balic, Sebastian, Hollizeck, Tom S, Weber, Timothy, Semple, Qing, Wang, Denise C, Miles, Laura, MacPherson, Yih-Chih, Chan, Andrew A, Guirguis, Lev M, Kats, Emily S, Wong, Sarah-Jane, Dawson, Shalin H, Naik, Mark A, Dawson
Publikováno v:
Nature. 601(7891)
All cancers emerge after a period of clonal selection and subsequent clonal expansion. Although the evolutionary principles imparted by genetic intratumour heterogeneity are becoming increasingly clear
Autor:
Olivia Stonehouse, Philip D. Hodgkin, Tom S. Weber, Tracey M. Baldwin, Samir Taoudi, Jai Rautela, Matthew E. Ritchie, Sara Tomei, Daniela Amann-Zalcenstein, Stephen L. Nutt, Dawn S. Lin, Ashley P. Ng, Nicholas D. Huntington, Luyi Tian, Shalin H. Naik, Jaring Schreuder
Publikováno v:
Nature cell biology. 23(3)
Regulation of haematopoietic stem and progenitor cell (HSPC) fate is crucial during homeostasis and under stress conditions. Here we examine the aetiology of the Flt3 ligand (Flt3L)-mediated increase of type 1 conventional dendritic cells (cDC1s). Us
Autor:
Stephen L. Nutt, Tracey M. Baldwin, Jaring Schreuder, Shalin H. Naik, Nicholas D. Huntington, Olivia Stonehouse, Samir Taoudi, Philip D. Hodgkin, Jai Rautela, Daniela Amann-Zalcenstein, Sara Tomei, Tom S. Weber, Luyi Tian, Ashley P. Ng, Matthew E. Ritchie, Dawn S. Lin
SummaryExtrinsic regulation of single haematopoietic stem and progenitor cell (HSPC) fate is crucial for immune cell development. Here, we examine the aetiology of Flt3 ligand (Flt3L)-mediated emergency development of type 1 conventional dendritic ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f97b3b81c1e46df112a80117374faae8
https://doi.org/10.1101/2020.05.28.120188
https://doi.org/10.1101/2020.05.28.120188
Autor:
Lev Kats, Peter Diakumis, Timothy Patton, Sara Tomei, Cindy Audiger, Meredith O'Keeffe, Toby Sargeant, Shalin H. Naik, Daniela Amann-Zalcenstein, Jessica Tran, Melanie Bahlo, Ee Shan Pang, Luyi Tian, Matthew E. Ritchie, Dawn S. Lin, Ashley P. Ng, Madison J. Kelly, Adrienne A. Hilton, Andrew Jarratt, Tracy A. Willson, Jaring Schreuder, Tom S. Weber, Quentin Gouil, Mathew Chu, Philip D. Hodgkin, Shian Su
Publikováno v:
Immunity. 54:1338-1351.e9
Despite advances in single-cell multi-omics, a single stem or progenitor cell can only be tested once. We developed clonal multi-omics, in which daughters of a clone act as surrogates of the founder, thereby allowing multiple independent assays per c