Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Tom Rolf"'
Autor:
Rhea N. Coler, Tracey A. Day, Ruth Ellis, Franco M. Piazza, Anna Marie Beckmann, Julie Vergara, Tom Rolf, Lenette Lu, Galit Alter, David Hokey, Lakshmi Jayashankar, Robert Walker, Margaret Ann Snowden, Tom Evans, Ann Ginsberg, Steven G. Reed, The TBVPX-113 Study Team
Publikováno v:
npj Vaccines, Vol 3, Iss 1, Pp 1-9 (2018)
NPJ Vaccines
NPJ Vaccines
Tuberculosis (TB) is the leading cause of infectious death worldwide. Development of improved TB vaccines that boost or replace BCG is a major global health goal. ID93 + GLA-SE is a fusion protein TB vaccine candidate combined with the Toll-like Rece
Autor:
Julia Amsterdam, Alessandro Companie, Fajwa Opperman, Justin Shenje, Steven G. Reed, Elma Van Rooyen, Sandra Goliath, Julia Noble, Tom Rolf, Friedrich Thienemann, Ann Swarts, Rhea N. Coler, Amaryl Van Schalkwyk, Linda-Gail Bekker, Sarah Albertson, Alessandro Sette, Erica Smit, Angelique Mouton, Michele Tameris, Zachary K. Sagawa, Lebohang Makhethe, Yolandi Herselman, Aude Frevol, Yolundi Cloete, Simbarashe Mabwe, Nicole Bilek, Angelique Kany Kany Luabeya, Alana Keyser, Cecilia S. Lindestam Arlehamn, Andrew Fiore-Gartland, Tracey A. Day, Asma Toefy, Carolyn Jones, Thomas J. Scriba, Linda van der Merwe, Constance Schreuder, Natasja Botes, Susan Rossouw, Andreas H. Diacon, Humphrey Mulenga, Adam Penn-Nicholson, Devona Hofmeester, Sandra Kruger, Nelita du Plessis, Fan-Chi Hsu, Jill A. Ashman, Julie Vergara, Anna Marie Beckmann, Eunice Sinandile, Andre G. Loxton, Elisabeth Filander, Ashley Veldsman, Andrea Gutschmidt, Marwou de Kock, Leya Hassanally, Hadn Africa, Stuart Kahn, Yiwen Lu, Marcia Steyn, Timothy D. Reid, Gerhard Walzl, Gail Jacobs, Elize van der Riet, Mark Hatherill, Cynthia Ontong, Nambitha Quaqua, H. Geldenhuys
Publikováno v:
The Lancet. Respiratory medicine. 9(4)
Summary Background A therapeutic vaccine that prevents recurrent tuberculosis would be a major advance in the development of shorter treatment regimens. We aimed to assess the safety and immunogenicity of the ID93 + GLA-SE vaccine at various doses an
Autor:
Tracey A Day, Darrick Carter, Tom Rolf, Malcolm S. Duthie, Jeffrey A. Guderian, Hong Liang, Steven G. Reed, Zachary K. Sagawa, Anthony L. Desbien, Mark T. Orr, Christopher B. Fox, Rhea N. Coler, Julie Vergara, Greg C. Ireton
Publikováno v:
Clinical & Translational Immunology
Adjuvants are combined with vaccine antigens to enhance and modify immune responses, and have historically been primarily crude, undefined entities. Introducing toll-like receptor (TLR) ligands has led to a new generation of adjuvants, with TLR4 liga