Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tom R Geisbush"'
Autor:
Jia Li, Tom R Geisbush, William D Arnold, Glenn D Rosen, Phillip G Zaworski, Seward B Rutkove
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111428 (2014)
OBJECTIVES:There is a need for better, noninvasive quantitative biomarkers for assessing the rate of progression and possible response to therapy in spinal muscular atrophy (SMA). In this study, we compared three electrophysiological measures: compou
Externí odkaz:
https://doaj.org/article/b447b257d2d344159e88b398c2f64ddd
Publikováno v:
Neurographics. 10:88-91
A congenital dilated imperforate submandibular duct is a rare condition that presents early in neonates. Treatment can vary considerably from other lesions more commonly found in the floor of the mouth. Here we describe the case of a 1-week-old neona
Publikováno v:
Interv Neuroradiol
The use of flow diverting stents for wide based, intracranial aneurysms has become an invaluable treatment option. While intracranial hemorrhage and ischemic stroke from dislodged atherosclerotic emboli are common adverse events, the potential for de
Autor:
Adam Pacheck, Tom R. Geisbush, Courtney E. McIlduff, Sung Yim, Seward B. Rutkove, Aleksandar S. Mijailovic
Publikováno v:
Clinical Neurophysiology. 127:932-935
Objectives Electrical impedance myography (EIM) measurements of the tongue could provide valuable information about bulbar dysfunction in amyotrophic lateral sclerosis (ALS). A prototype tongue depressor EIM array produced gag reflexes. The objective
Publikováno v:
Muscle & Nerve. 52:598-604
Introduction: Similar to magnetic resonance imaging (MRI), electrical impedance myography (EIM) is dependent on the presence and location of water in muscle to assess neuromuscular diseases. We compared the 2 technologies in mdx mice to better unders
Autor:
Aleksandar S. Mijailovic, Stefan Schwartz, Tom R. Geisbush, Seward B. Rutkove, Amy Pasternak, Basil T. Darras
Publikováno v:
Clinical Neurophysiology. 126:202-208
Electrical impedance myography (EIM) is an electrophysiological technique for neuromuscular evaluation that is impacted by subcutaneous fat (SF). Exploiting the differing frequency dependences of muscle and fat, we assessed a 2-frequency EIM phase ra
Autor:
Aleksandar S. Mijialovic, Tom R. Geisbush, Seward B. Rutkove, Basil T. Darras, Jim S. Wu, Craig M. Zaidman, Irina Shklyar, Amy Pasternak
Publikováno v:
Muscle & Nerve. 51:207-213
Introduction Muscle pathology in Duchenne muscular dystrophy (DMD) can be quantified using ultrasound by measuring either the amplitudes of sound-waves scattered back from the tissue [quantitative backscatter analysis (QBA)] or by measuring these bac
Autor:
Anthony R. West, Shreaya Chakroborty, Alan L. Pehrson, Tom R. Geisbush, Elena Dale, Connie Sanchez
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 8 (2017)
Chakroborty, S, Geisbush, T R, Dale, E, Pehrson, A L, Sanchez, C & West, A R 2017, ' Impact of Vortioxetine on Synaptic Integration in Prefrontal-Subcortical Circuits : Comparisons with Escitalopram ', Frontiers in Pharmacology, vol. 8, 764 . https://doi.org/10.3389/fphar.2017.00764
Frontiers in Pharmacology, Vol 8 (2017)
Chakroborty, S, Geisbush, T R, Dale, E, Pehrson, A L, Sanchez, C & West, A R 2017, ' Impact of Vortioxetine on Synaptic Integration in Prefrontal-Subcortical Circuits : Comparisons with Escitalopram ', Frontiers in Pharmacology, vol. 8, 764 . https://doi.org/10.3389/fphar.2017.00764
Prefrontal-subcortical circuits support executive functions which often become dysfunctional in psychiatric disorders. Vortioxetine is a multimodal antidepressant that is currently used in the clinic to treat major depressive disorder. Mechanisms of
Autor:
Jim S. Wu, Nicole Visyak, Craig M. Zaidman, Tom R. Geisbush, Seward B. Rutkove, Basil T. Darras, Amy Pasternak, Aleksandar S. Mijailovic, Irina Shklyar
Publikováno v:
Pediatric Neurology. 51:88-92
Electrical impedance myography and quantitative ultrasound are two noninvasive, painless, and effort-independent approaches for assessing neuromuscular disease. Both techniques have potential to serve as useful biomarkers in clinical trials in Duchen
Publikováno v:
Muscle & Nerve. 49:829-835
Introduction: Sensitive, non-invasive techniques are needed that can provide biomarkers of disease status and the effects of therapy in muscular dystrophy. Methods: We evaluated electrical impedance myography (EIM) to serve in this role by studying 2