Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tom Quaiser"'
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 8, p e1007961 (2020)
Tumour spheroids are widely used as an in vitro assay for characterising the dynamics and response to treatment of different cancer cell lines. Their popularity is largely due to the reproducible manner in which spheroids grow: the diffusion of nutri
Externí odkaz:
https://doaj.org/article/99d7b95699f64d4489e431f58cdd5e9a
Autor:
David Johnson, Anthony J. Connor, Steve McKeever, Zhihui Wang, Thomas S. Deisboeck, Tom Quaiser, Eliezer Shochat
Publikováno v:
Cancer Informatics, Vol 2014, Iss Suppl. 1, Pp 133-143 (2014)
Externí odkaz:
https://doaj.org/article/3c17407ffae6410dbbc1e8b2815f88f9
Autor:
Tom Quaiser, Sarah L. Waters, Philip S. Macklin, Christopher W. Pugh, Helen M. Byrne, Franziska Braun, Joshua A. Bull
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Digital pathology enables computational analysis algorithms to be applied at scale to histological images. An example is the identification of immune cells within solid tumours. Image analysis algorithms can extract precise cell locations from immuno
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 16, Iss 8, p e1007961 (2020)
PLoS Computational Biology, Vol 16, Iss 8, p e1007961 (2020)
Tumour spheroids are widely used as an in vitro assay for characterising the dynamics and response to treatment of different cancer cell lines. Their popularity is largely due to the reproducible manner in which spheroids grow: the diffusion of nutri
Autor:
Eduard Resch, Tom Quaiser, Anna Starzinski-Powitz, Gisbert Schneider, Alexander Schreiner, Saskia Quaiser
Publikováno v:
Traffic. 9:1344-1353
Signal peptides (SP) and transmembrane segments (TMS) ensure proper subcellular targeting and localization of proteins. Thus, understanding the molecular variability of this targeting information is essential. In this study, we functionally analyzed
Autor:
Philip K. Maini, Joe Pitt-Francis, Jonathan Cooper, Erica Lorenzon, Frank Herting, Markus Thomas, Tom Quaiser, Helen M. Byrne, Radosław P. Nowak, Eliezer Shochat, Stefan Hoert, Anthony J. Connor
Publikováno v:
Interface. 12(110)
Angiogenesis, the process by which new vessels form from existing ones, plays an important role in many developmental processes and pathological conditions. We study angiogenesis in the context of a highly controllable experimental environment: the c
Publikováno v:
BMC Systems Biology
BMC systems biology 5, 30 (2011). doi:10.1186/1752-0509-5-30
BMC Systems Biology, Vol 5, Iss 1, p 30 (2011)
BMC systems biology 5, 30 (2011). doi:10.1186/1752-0509-5-30
BMC Systems Biology, Vol 5, Iss 1, p 30 (2011)
BMC systems biology 5, 30 (2011). doi:10.1186/1752-0509-5-30
Published by BioMed Central, London
Published by BioMed Central, London
Autor:
Tom Quaiser, Martin Mönnigmann
Publikováno v:
BMC Systems Biology
BMC systems biology 3, (2009). doi:10.1186/1752-0509-3-50 special issue: "2nd International Conference on Foundations of Systems Biology in Engineering, Stuttgart, Germany, Sep, 2007"
BMC Systems Biology, Vol 3, Iss 1, p 50 (2009)
BMC systems biology 3, (2009). doi:10.1186/1752-0509-3-50 special issue: "2nd International Conference on Foundations of Systems Biology in Engineering, Stuttgart, Germany, Sep, 2007"
BMC Systems Biology, Vol 3, Iss 1, p 50 (2009)
Background When creating mechanistic mathematical models for biological signaling processes it is tempting to include as many known biochemical interactions into one large model as possible. For the JAK-STAT, MAP kinase, and NF-κ B pathways a lot of
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 28(4)
Wnt proteins form a family of secreted signaling proteins that play a key role in various developmental events such as cell differentiation, cell migration, cell polarity and cell proliferation. It is currently thought that Wnt proteins activate at l
Autor:
Zhihui Wang, Steve McKeever, Tom Quaiser, Eliezer Shochat, Anthony J. Connor, David Johnson, Thomas S. Deisboeck
Publikováno v:
Cancer Informatics, Vol 13s1 (2014)
Cancer Informatics
Cancer Informatics, Vol 2014, Iss Suppl. 1, Pp 133-143 (2014)
Cancer Informatics
Cancer Informatics, Vol 2014, Iss Suppl. 1, Pp 133-143 (2014)
Multiscale models are commonplace in cancer modeling, where individual models acting on different biological scales are combined within a single, cohesive modeling framework. However, model composition gives rise to challenges in understanding interf