Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Tom P Monie"'
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e76237 (2013)
Autophagy is a fundamental cellular process required for organelle degradation and removal of invasive pathogens. Autophagosome formation involves the recruitment of, and interaction between, multiple proteins produced from autophagy-related (ATG) ge
Externí odkaz:
https://doaj.org/article/a824037531144a2ab38db6f2186195b4
Autor:
Ricardo Núñez Miguel, Joyce Wong, Julian F Westoll, Heather J Brooks, Luke A J O'Neill, Nicholas J Gay, Clare E Bryant, Tom P Monie
Publikováno v:
PLoS ONE, Vol 2, Iss 8, p e788 (2007)
The Toll-like receptor 4 (TLR4) is a class I transmembrane receptor expressed on the surface of immune system cells. TLR4 is activated by exposure to lipopolysaccharides derived from the outer membrane of Gram negative bacteria and forms part of the
Externí odkaz:
https://doaj.org/article/079e7fe1244f4808a5ecec4901e95213
Autor:
Tom P. Monie, Clare Bryant
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Pattern Recognition Receptors (PRRs, [110]) (nomenclature as agreed by NC-IUPHAR sub-committee on Pattern Recognition Receptors, [20]) participate in the innate immune response to microbial agents, the stimulation of which leads to activation of intr
Autor:
Tom P. Monie, Simon D. Harding, Csaba Szabó, Lincoln R. Potter, Stephen P.H. Alexander, Peter Brouckaert, Jamie A. Davies, Harald H.H.W. Schmidt, Elena Faccenda, Christopher Southan, Eamonn Kelly, John Garthwaite, Scott A. Waldman, Jane F. Armstrong, Andreas Papapetropoulos, Michaela Kuhn, Adam J. Pawson, John A. Peters, David J. MacEwan, John C. Burnett, Clare E. Bryant, Annie Beuve, Richard W. Farndale, Andreas Friebe, Adrian J. Hobbs, Emma L. Veale, Gavin E. Jarvis, Alistair Mathie, Doriano Fabbro
Publikováno v:
British Journal of Pharmacology, 178, S264-S312. Wiley
BRITISH JOURNAL OF PHARMACOLOGY
BRITISH JOURNAL OF PHARMACOLOGY
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on select
Autor:
Tom P. Monie, Clare E. Bryant
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2021
Pattern Recognition Receptors (PRRs, [104]) (nomenclature as agreed by NC-IUPHAR sub-committee on Pattern Recognition Receptors, [18]) participate in the innate immune response to microbial agents, the stimulation of which leads to activation of intr
Autor:
Robert J. Pickering, Lee Hopkins, Panagiotis Tourlomousis, Joseph P. Boyle, James Rooney, Tom P. Monie, Søren Warming, Nobuhiko Kayagaki, Betsaida Bibo-Verdugo, Zsofia Digby, Steve J. Webster, Guy S. Salvesen, Clare E. Bryant, Lucy A. Weinert
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109614-(2021)
Cell Reports
Cell Reports
Summary Zoonotic pathogens, such as COVID-19, reside in animal hosts before jumping species to infect humans. The Carnivora, like mink, carry many zoonoses, yet how diversity in host immune genes across species affect pathogen carriage is poorly unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df4b31528ec19572257040cf0ef6a0e
https://www.repository.cam.ac.uk/handle/1810/326412
https://www.repository.cam.ac.uk/handle/1810/326412
Publikováno v:
Open Biology, Vol 4, Iss 12 (2014)
The cytosolic pattern recognition receptor NOD2 is activated by the peptidoglycan fragment muramyl dipeptide to generate a proinflammatory immune response. Downstream effects include the secretion of cytokines such as interleukin 8, the upregulation
Externí odkaz:
https://doaj.org/article/5e6df64afcc04d46baa9ae26868279fa
Autor:
Zsofia Digby, Robert J. Pickering, Lee Hopkins, Nobuhiko Kayagaki, Joseph P. Boyle, Betsy Bibo Verdugo, Clare E. Bryant, Tom P. Monie, Søren Warming, James Rooney, Guy S. Salvesen, Steve J. Webster, Lucy A. Weinert
Publikováno v:
SSRN Electronic Journal.
Zoonotic infections, such as COVID-19, reside in animal hosts before jumping species to humans. The Carnivora, like mink, carry many zoonoses yet how diversity in host immune genes across species impact upon pathogen carriage are poorly understood. H
Autor:
Tom P. Monie, Rachel E. Hewitt, Bradley Vis, Jonathan J. Powell, Stephen D. Kinrade, Camilla Fairbairn, Suzanne D. Turner
Publikováno v:
Proc Natl Acad Sci U S A
The impact of ultrasmall nanoparticles (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf5c449d9e2bd78c3a99496d57a0fc5
https://www.repository.cam.ac.uk/handle/1810/300665
https://www.repository.cam.ac.uk/handle/1810/300665
Publikováno v:
Clinical and Developmental Immunology, Vol 2011 (2011)
The gastrointestinal microbiota is a major source of immune stimulation. The interaction between host pattern-recognition receptors and conserved microbial ligands profoundly influences infection dynamics. Identifying and understanding the nature of
Externí odkaz:
https://doaj.org/article/70e9610d71e54acabbb3667e5ffdf7eb