Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tom Manczak"'
Autor:
Trine Bundgaard Andersen, Carmen Quiñonero López, Tom Manczak, Karen Martinez, Henrik Toft Simonsen
Publikováno v:
Molecules, Vol 20, Iss 4, Pp 6113-6127 (2015)
The sesquiterpene lactone thapsigargin is found in the plant Thapsia garganica L., and is one of the major constituents of the roots and fruits of this Mediterranean species. In 1978, the first pharmacological effects of thapsigargin were established
Externí odkaz:
https://doaj.org/article/75fb1e821dd241ee86ce451a26082541
Autor:
Tom Manczak, Trine Bundgaard Andersen, Carmen Quinonero Lopez, Karen Agatha Martinez, Henrik Toft Simonsen
Publikováno v:
Molecules
Andersen, T B, Quinonero Lopez, C, Manczak, T, Martinez, K A & Simonsen, H T 2015, ' Thapsigargin-from Thapsia L. to Mipsagargin ', Molecules, vol. 20, no. 4, pp. 6113-6127 . https://doi.org/10.3390/molecules20046113
Molecules, Vol 20, Iss 4, Pp 6113-6127 (2015)
Andersen, T B, Quinonero Lopez, C, Manczak, T, Martinez, K A & Simonsen, H T 2015, ' Thapsigargin-from Thapsia L. to Mipsagargin ', Molecules, vol. 20, no. 4, pp. 6113-6127 . https://doi.org/10.3390/molecules20046113
Molecules, Vol 20, Iss 4, Pp 6113-6127 (2015)
The sesquiterpene lactone thapsigargin is found in the plant Thapsia garganica L., and is one of the major constituents of the roots and fruits of this Mediterranean species. In 1978, the first pharmacological effects of thapsigargin were established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5941d8a515767e28709e65175bd0df4c
https://doi.org/10.3390/molecules20046113
https://doi.org/10.3390/molecules20046113
Autor:
Thomas Sundelin, Tom Manczak, Mikael Agerlin Petersen, Henrik Toft Simonsen, Birgit Jensen, Maciej Grajewski, Daniel Buchvaldt Amby, Corinna Weitzel
Publikováno v:
Amby, D B, Manczak, T, Petersen, M A, Sundelin, T, Weitzel, C, Grajewski, M, Simonsen, H T & Jensen, B 2016, ' Role of the Colletotrichum acutatum sesquiterpene synthase Ca TPS in the biosynthesis of sesquiterpenoids ', Microbiology, vol. 162, no. 10, pp. 1773-1783 . https://doi.org/10.1099/mic.0.000361
Colletotrichum acutatum is a major fungal pathogen of fruit crops, which causes severe yield losses in strawberry production. A potential key factor in plant–pathogen interactions is fungal sesquiterpenoids which have mycotoxic and phytotoxic activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f8a41b3550ecb7f76f786fdf57a09e3
https://curis.ku.dk/portal/da/publications/role-of-the-colletotrichum-acutatum-sesquiterpene-synthase-catps-in-the-biosynthesis-of-sesquiterpenoids(6ef80bc3-a0d5-4107-be64-8b62d8714b35).html
https://curis.ku.dk/portal/da/publications/role-of-the-colletotrichum-acutatum-sesquiterpene-synthase-catps-in-the-biosynthesis-of-sesquiterpenoids(6ef80bc3-a0d5-4107-be64-8b62d8714b35).html
Autor:
Henrik Toft Simonsen, Corinna Weitzel, Tom Manczak, Damian P. Drew, Dae-Kyun Ro, Benjamin Pickel
Publikováno v:
Biochemical Journal. 448:261-271
Thapsigargin is a major terpenoid constituent of Thapsia garganica root. Owing to its potent antagonistic effect on the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase, thapsigargin has been widely used to study Ca2+ signalling and is also a potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b2e358156d2a7ce2843055349dd480
https://doi.org/10.1042/bj20120654
https://doi.org/10.1042/bj20120654
Autor:
Henrik Toft Simonsen, Tom Manczak
Publikováno v:
Manczak, T & Simonsen, H T 2016, ' Insight into Biochemical Characterization of Plant Sesquiterpene Synthases ', Analytical Chemistry Insights, vol. 11, no. S1 . https://doi.org/10.4137/ACI.S40292
Manczak, T & Simonsen, H T 2016, ' Insight into biochemical characterization of plant sesquiterpene synthases ', Analytical Chemistry Insights, vol. 11, no. Suppl. 1, pp. 1-7 . https://doi.org/10.4137/ACI.S40292
Analytical Chemistry Insights, Vol 11s1 (2016)
Analytical Chemistry Insights
Analytical Chemistry Insights, Vol 2016, Iss Suppl. 1, Pp 1-7 (2016)
Manczak, T & Simonsen, H T 2016, ' Insight into biochemical characterization of plant sesquiterpene synthases ', Analytical Chemistry Insights, vol. 11, no. Suppl. 1, pp. 1-7 . https://doi.org/10.4137/ACI.S40292
Analytical Chemistry Insights, Vol 11s1 (2016)
Analytical Chemistry Insights
Analytical Chemistry Insights, Vol 2016, Iss Suppl. 1, Pp 1-7 (2016)
A fast and reproducible protocol was established for enzymatic characterization of plant sesquiterpene synthases that can incorporate radioactivity in their products. The method utilizes the 96-well format in conjunction with cluster tubes and enable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2072ba93f623eecb2997b7b97581d57d
https://doi.org/10.4137/aci.s40292
https://doi.org/10.4137/aci.s40292
Autor:
Madeleine Dahlbäck, Thor G. Theander, Mafalda Resende, Sisse B. Ditlev, Ali Salanti, Tom Manczak, Vera V. Pinto, Morten Nielsen, Gorm Andersen
Publikováno v:
Malaria Journal, Vol 9, Iss 1, p 11 (2010)
Malaria Journal
Malaria Journal
Background Malaria caused by Plasmodium falciparum can result in several different syndromes with severe clinical consequences for the about 200 million individuals infected each year. During pregnancy, women living in endemic areas become susceptibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8815534011097b6f4062597484d55bd
http://www.malariajournal.com/content/9/1/11
http://www.malariajournal.com/content/9/1/11