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pro vyhledávání: '"Tom M. Thomas"'
Autor:
John S. Yu, J. Manuel Perez, Roberta A. Gottlieb, Kamel Khalili, Miqin Zhang, Allen M. Andres, Justin S. Michael, Daniel Braas, Yizhou Wang, Ramachandran Murali, Li Aiguo, Hassen Wollebo, Hongqiang Wang, Lincoln A. Edwards, Ken Miyaguchi, Tom M. Thomas
S1. Clinical and molecular profile of gliomas by ASNS status S2. CDKN2A and ASNS KM survival plots by IDH status S3. ASNS copy-number gain compared to ASNS mRNA & protein expression S4. IDH mutation inversely correlate to ASNS copy number gain S5. GS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3940a3168f3c4aa132950083fdc0f2
https://doi.org/10.1158/1541-7786.22517671.v1
https://doi.org/10.1158/1541-7786.22517671.v1
Autor:
John S. Yu, J. Manuel Perez, Roberta A. Gottlieb, Kamel Khalili, Miqin Zhang, Allen M. Andres, Justin S. Michael, Daniel Braas, Yizhou Wang, Ramachandran Murali, Li Aiguo, Hassen Wollebo, Hongqiang Wang, Lincoln A. Edwards, Ken Miyaguchi, Tom M. Thomas
Asparagine synthetase (ASNS) is a gene on the long arm of chromosome 7 that is copy-number amplified in the majority of glioblastomas. ASNS copy-number amplification is associated with a significantly decreased survival. Using patient-derived glioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095bdac82cdf7d36a96ec56ba3662c92
https://doi.org/10.1158/1541-7786.c.6541795.v1
https://doi.org/10.1158/1541-7786.c.6541795.v1
Publikováno v:
Advances in experimental medicine and biology. 853
For decades human brain tumors have confounded our efforts to effectively manage and treat patients. In adults, glioblastoma multiforme is the most common malignant brain tumor with a patient survival of just over 14 months. In children, brain tumors