Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Tom Lue"'
Autor:
Istvan Kovanecz, Robert Gelfand, Sheila Sharifzad, Alec Ohanian, William Brent DeCastro, Carley Cooper, Guiting Lin, Tom Lue, Nestor F. Gonzalez-Cadavid
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 5045 (2020)
Human stem cell therapy for type 2 diabetes/obesity (T2D/O) complications is performedwith stem cell autografts, exposed to the noxious T2D/O milieu, often with suboptimal results.We showed in the Obese Zucker (OZ) rat model of T2D/O that when their
Externí odkaz:
https://doaj.org/article/5e7785fbfefb480b9e48042b46e5f5de
Autor:
Istvan Kovanecz, Robert Gelfand, Guiting Lin, Sheila Sharifzad, Alec Ohanian, Randy Ricks, Tom Lue, Nestor F. Gonzalez-Cadavid
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 16, p 4044 (2019)
Female stress urinary incontinence (FSUI) is prevalent in women with type 2 diabetes/obesity (T2D/O), and treatment is not optimal. Autograph stem cell therapy surprisingly has poor efficacy. In the male rat model of T2D/O, it was demonstrated that e
Externí odkaz:
https://doaj.org/article/2baaa800a3084d2cb82627629e1bb185
Bone mineral density as a prognostic marker in patients with biliary tract cancer undergoing surgery
Autor:
Lisa Heinrichs, Georg Fluegen, Sven H. Loosen, Christina Loberg, Linda Wittig, Alexander Quaas, Patrick S. Plum, Nils Große Hokamp, Peter Minko, Andreas Krieg, Gerald Antoch, Wolfram T. Knoefel, Tom Luedde, Christoph Roderburg, Markus S. Jördens
Publikováno v:
BJC Reports, Vol 2, Iss 1, Pp 1-8 (2024)
Abstract Background Biliary tract cancer (BTC) is one of the most aggressive malignancies and surgery represents the only curative treatment approach. However, even in patients with complete tumor resection 5-year survival rates are below 30%. So far
Externí odkaz:
https://doaj.org/article/84a7fbf3c8d34f49a0f345ec8141c311
Publikováno v:
Gastroenterology Insights, Vol 15, Iss 3, Pp 764-785 (2024)
Background: The induced repolarization of tumor growth-promoting M2 macrophages into tumor growth-inhibiting M1 macrophages is a matter of intensive research and is expected to lead towards a novel targetable approach in HCC therapy. Methods: Differe
Externí odkaz:
https://doaj.org/article/76d77d6e0376414e835e5f58726358ea
Autor:
Carsten Berndt, Hamed Alborzinia, Vera Skafar Amen, Scott Ayton, Uladzimir Barayeu, Alexander Bartelt, Hülya Bayir, Christina M. Bebber, Kivanc Birsoy, Jan P. Böttcher, Simone Brabletz, Thomas Brabletz, Ashley R. Brown, Bernhard Brüne, Giorgia Bulli, Alix Bruneau, Quan Chen, Gina M. DeNicola, Tobias P. Dick, Ayelén Distéfano, Scott J. Dixon, Jan B. Engler, Julia Esser-von Bieren, Maria Fedorova, José Pedro Friedmann Angeli, Manuel A. Friese, Dominic C. Fuhrmann, Ana J. García-Sáez, Karolina Garbowicz, Magdalena Götz, Wei Gu, Linda Hammerich, Behrouz Hassannia, Xuejun Jiang, Aicha Jeridi, Yun Pyo Kang, Valerian E. Kagan, David B. Konrad, Stefan Kotschi, Peng Lei, Marlène Le Tertre, Sima Lev, Deguang Liang, Andreas Linkermann, Carolin Lohr, Svenja Lorenz, Tom Luedde, Axel Methner, Bernhard Michalke, Anna V. Milton, Junxia Min, Eikan Mishima, Sebastian Müller, Hozumi Motohashi, Martina U. Muckenthaler, Shohei Murakami, James A. Olzmann, Gabriela Pagnussat, Zijan Pan, Thales Papagiannakopoulos, Lohans Pedrera Puentes, Derek A. Pratt, Bettina Proneth, Lukas Ramsauer, Raphael Rodriguez, Yoshiro Saito, Felix Schmidt, Carina Schmitt, Almut Schulze, Annemarie Schwab, Anna Schwantes, Mariluz Soula, Benedikt Spitzlberger, Brent R. Stockwell, Leonie Thewes, Oliver Thorn-Seshold, Shinya Toyokuni, Wulf Tonnus, Andreas Trumpp, Peter Vandenabeele, Tom Vanden Berghe, Vivek Venkataramani, Felix C.E. Vogel, Silvia von Karstedt, Fudi Wang, Frank Westermann, Chantal Wientjens, Christoph Wilhelm, Michele Wölk, Katherine Wu, Xin Yang, Fan Yu, Yilong Zou, Marcus Conrad
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103211- (2024)
Ferroptosis is a pervasive non-apoptotic form of cell death highly relevant in various degenerative diseases and malignancies. The hallmark of ferroptosis is uncontrolled and overwhelming peroxidation of polyunsaturated fatty acids contained in membr
Externí odkaz:
https://doaj.org/article/704bf377a6004407992c3cd92011cf30
Autor:
Tom Luedde, Karel Kostev, Christoph Roderburg, Jennis Kandler, Alexander Mertens, Sven Heiko Loosen, Isabel Klein, Catherine Leyh, Sarah Krieg
Publikováno v:
BMJ Open Gastroenterology, Vol 11, Iss 1 (2024)
Background Helicobacter pylori (H. pylori) is a gram-negative gastrointestinal pathogen that colonises the human stomach and is considered a major risk factor for gastric cancer and mucosa-associated lymphoid tissue lymphoma. Furthermore, H. pylori i
Externí odkaz:
https://doaj.org/article/fa785caf714245de90b10effb8de5b4f
Autor:
Kaneschka Yaqubi, Karel Kostev, Isabel Klein, Sofia Schüssler, Petra May, Tom Luedde, Christoph Roderburg, Sven H. Loosen
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-7 (2024)
Abstract Background Recent data suggest a potential pathophysiological link between inflammatory bowel disease (IBD) and multiple sclerosis (MS), two immune-mediated diseases both of which can have a significant impact on patients' quality of life. I
Externí odkaz:
https://doaj.org/article/40ddeff5a8e44339be69c1c14e54a6aa
Autor:
Sven H. Loosen, Fabian Benz, Raphael Mohr, Philipp A. Reuken, Theresa H. Wirtz, Lioba Junker, Christian Jansen, Carsten Meyer, Michael Praktiknjo, Alexander Wree, Johanna Reißing, Münevver Demir, Wenyi Gu, Mihael Vucur, Robert Schierwagen, Andreas Stallmach, Anselm Kunstein, Johannes Bode, Christian Trautwein, Frank Tacke, Tom Luedde, Tony Bruns, Jonel Trebicka, Christoph Roderburg
Publikováno v:
JHEP Reports, Vol 6, Iss 5, Pp 101054- (2024)
Background & Aims: Transjugular intrahepatic portosystemic shunt (TIPS) is the most effective therapy for complications of portal hypertension. However, clinical outcomes following TIPS placement vary widely between patients and identifying ideal can
Externí odkaz:
https://doaj.org/article/1c0266d113654c7496f7e96b4601da0f
Autor:
Alexander Killer, Smaranda Gliga, Carolin Lohr, Christian Weigel, Björn-Erik Ole Jensen, Nadine Lübke, Andreas Walker, Jörg Timm, Johannes Bode, Tom Luedde, Hans H. Bock
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 3, Pp 353-360 (2024)
Background and Aims: The entry inhibitor bulevirtide represents the first specific treatment for hepatitis-D virus (HDV)-infected patients. In clinical trials, around 80% of patients achieve normalization of alanine aminotransferase (ALT) with about
Externí odkaz:
https://doaj.org/article/20cc424499e749c1ab58893002175fbd
Autor:
Julien Calderaro, Narmin Ghaffari Laleh, Qinghe Zeng, Pascale Maille, Loetitia Favre, Anaïs Pujals, Christophe Klein, Céline Bazille, Lara R. Heij, Arnaud Uguen, Tom Luedde, Luca Di Tommaso, Aurélie Beaufrère, Augustin Chatain, Delphine Gastineau, Cong Trung Nguyen, Hiep Nguyen-Canh, Khuyen Nguyen Thi, Viviane Gnemmi, Rondell P. Graham, Frédéric Charlotte, Dominique Wendum, Mukul Vij, Daniela S. Allende, Federico Aucejo, Alba Diaz, Benjamin Rivière, Astrid Herrero, Katja Evert, Diego Francesco Calvisi, Jérémy Augustin, Wei Qiang Leow, Howard Ho Wai Leung, Emmanuel Boleslawski, Mohamed Rela, Arnaud François, Anthony Wing-Hung Cha, Alejandro Forner, Maria Reig, Manon Allaire, Olivier Scatton, Denis Chatelain, Camille Boulagnon-Rombi, Nathalie Sturm, Benjamin Menahem, Eric Frouin, David Tougeron, Christophe Tournigand, Emmanuelle Kempf, Haeryoung Kim, Massih Ningarhari, Sophie Michalak-Provost, Purva Gopal, Raffaele Brustia, Eric Vibert, Kornelius Schulze, Darius F. Rüther, Sören A. Weidemann, Rami Rhaiem, Jean-Michel Pawlotsky, Xuchen Zhang, Alain Luciani, Sébastien Mulé, Alexis Laurent, Giuliana Amaddeo, Hélène Regnault, Eleonora De Martin, Christine Sempoux, Pooja Navale, Maria Westerhoff, Regina Cheuk-Lam Lo, Jan Bednarsch, Annette Gouw, Catherine Guettier, Marie Lequoy, Kenichi Harada, Pimsiri Sripongpun, Poowadon Wetwittayaklang, Nicolas Loménie, Jarukit Tantipisit, Apichat Kaewdech, Jeanne Shen, Valérie Paradis, Stefano Caruso, Jakob Nikolas Kather
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Primary liver cancer arises either from hepatocytic or biliary lineage cells, giving rise to hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (ICCA). Combined hepatocellular- cholangiocarcinomas (cHCC-CCA) exhibit equivocal
Externí odkaz:
https://doaj.org/article/ba65186be9624b389ea48c3c89596cfd