Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Tom L Broderick"'
Autor:
Marek Jankowski, Bogdan A Danalache, Eric Plante, Ahmed Menaouar, Maria Florian, Ju Jing Tan, Ryszard Grygorczyk, Tom L Broderick, Jolanta Gutkowska
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219205 (2019)
In the rat, oxytocin (OT) produces dose-dependent diuretic and natriuretic responses. Post-translational enzymatic conversion of the OT biosynthetic precursor forms both mature and C-terminally extended peptides. The plasma concentrations of these C-
Externí odkaz:
https://doaj.org/article/e514b943d6284392a20e364c2c53b396
Publikováno v:
Frontiers in Aging Neuroscience, Vol 6 (2014)
Alzheimer’s disease (AD) is a chronic neurodegenerative disorder characterized by a progressive loss of cognitive and behavioral abilities. Extracellular senile plaques and intracellular neurofibrillary tangles are hallmarks of AD. Researchers aim
Externí odkaz:
https://doaj.org/article/73e999ff695a4f82b8858a3da5c9ea4e
Autor:
Janelle Lopez, Layla Al-Nakkash, Tom L. Broderick, Monica Castro, Brielle Tobin, Jeffrey H. Plochocki
Publikováno v:
Metabolites, Vol 13, Iss 9, p 1014 (2023)
Type 2 diabetes mellitus and osteoarthritis (OA) often present as comorbidities. We examined the role of plasma IL-6, chondrocyte MMP-13, and col10a expression in the development of OA in obese diabetic mice. We further investigated dietary genistein
Externí odkaz:
https://doaj.org/article/4cebb495794d4b3889b9e136edb7af9e
Publikováno v:
Metabolites, Vol 13, Iss 3, p 438 (2023)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder associated with cognitive decline and characterized by amyloid-β plaques and neurofibrillary tau tangles. Although AD’s exact pathophysiology remains unclear, oxidative stress
Externí odkaz:
https://doaj.org/article/d4489dadd5524686bfd55cd9d684e20a
Publikováno v:
Kidney & Blood Pressure Research, Vol 42, Iss 3, Pp 398-405 (2017)
Background/Aims: Carnitine is essential for the transport of long-chain FAs (FA) into the mitochondria for energy production. During acute exercise, the increased demand for FAs results in a state of free carnitine deficiency in plasma. The role of k
Externí odkaz:
https://doaj.org/article/7cd702459cfb469e997686c8252439e1
Publikováno v:
Journal of Nutrition and Metabolism, Vol 2018 (2018)
We determined whether one single bout of exercise stimulates carnitine biosynthesis and carnitine uptake in liver and heart. Free carnitine (FC) in plasma was assayed using acetyltransferase and [14C]acetyl-CoA in Swiss Webster mice after 1 hour of m
Externí odkaz:
https://doaj.org/article/7bf9e27b9fec4911b09b4d100a702a0d
Autor:
Roman A. Beltran, Kyle J. Zemeir, Chase R. Kimberling, Mary S. Kneer, Michelle D. Mifflin, Tom L. Broderick
Publikováno v:
International journal of environmental research and public health. 19(24)
Introduction: In the United States, a significant amount of the population is affected by hyperlipidemia, which is associated with increased levels of serum low-density lipoprotein (LDL-C) and risk of cardiovascular disease. As of 2019, the guideline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf45ea01eeb45d62a964ec2dda1e68f
https://pubmed.ncbi.nlm.nih.gov/36554779
https://pubmed.ncbi.nlm.nih.gov/36554779
Autor:
Rongzi Li, Megan Robinson, Xiaowen Ding, Thangiah Geetha, Layla Al‐Nakkash, Tom L. Broderick, Jeganathan Ramesh Babu
Publikováno v:
Journal of food biochemistryREFERENCES. 46(7)
Neurodegenerative diseases are caused by the progressive loss of function or structure of nerve cells in the central nervous system. The most common neurodegenerative diseases include Alzheimer's disease, Huntington's disease, motor neuron disease, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd1c04dc1046fcfde972094c7cba2a7
https://pubmed.ncbi.nlm.nih.gov/35460092
https://pubmed.ncbi.nlm.nih.gov/35460092
Autor:
Rongzi Li, Jeganathan Ramesh Babu, Xiao-Wen Ding, Tom L. Broderick, Layla Al-Nakkash, Thangiah Geetha
Publikováno v:
Drug Design, Development and Therapy. 14:3325-3336
Purpose Diabetes mellitus (DM)-induced brain damage is characterized by cellular, molecular and functional changes. The mechanisms include oxidative stress, neuroinflammation, reduction of neurotrophic factors, insulin resistance, excessive amyloid b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b31933c4d3846d56f79297cb5b1b417
https://doi.org/10.2147/dddt.s249608
https://doi.org/10.2147/dddt.s249608
Publikováno v:
Diabetes, metabolic syndrome and obesity : targets and therapy. 15
Chaheyla R St Aubin,1 Amy L Fisher,1 Jose A Hernandez,2 Tom L Broderick,3,4 Layla Al-Nakkash3 1Department of Biomedical Sciences, College of Graduate Studies, Midwestern University, Glendale, AZ, 85308, USA; 2Department of Biochemistry and Molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f20a2af0e707a0984e278ac4f45cc14f
https://pubmed.ncbi.nlm.nih.gov/35911503
https://pubmed.ncbi.nlm.nih.gov/35911503