Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Tom Kruitwagen"'
Publikováno v:
eLife, Vol 4 (2015)
The segregation of eukaryotic chromosomes during mitosis requires their extensive folding into units of manageable size for the mitotic spindle. Here, we report on how phosphorylation at serine 10 of histone H3 (H3 S10) contributes to this process. U
Externí odkaz:
https://doaj.org/article/faa96747915d4ae58605988931c2bf4d
Autor:
Tom Kruitwagen, Thalia Martins Rebelo, Barbara Maierhofer, Gerwin Heller, Halenya Monticelli, Arthur G. Taveras, Chi Nguyen
Publikováno v:
Cancer Research. 83:5866-5866
Despite advances in therapies for B-cell lymphoma, patients may still develop resistance and often relapse. Contributing factors may include interactions between lymphoma cells (LCs) or leukemia cells and bone marrow microenvironment (BMM). Overexpre
Autor:
Chi Nguyen, Halenya Monticelli, Tom Kruitwagen, Matteo Tardelli, Barbara Maierhofer, Thalia Martins Rebelo, Sabine Maier-Munsa, Katarina Zmajkovicova, Lukas Dillinger, Adriana Badarau, Arthur G. Taveras
Publikováno v:
Cancer Research. 82:6093-6093
Waldenström’s macroglobulinemia (WM) is a rare B-cell malignancy characterized by monoclonal immunoglobulin M (IgM) hypersecretion and invasion of B cells in the bone marrow (BM) and lymphoid tissues. >90% of WM cases show mutations in MYD88 and 3
Publikováno v:
Cell, 175 (3)
Cell
Cell
Summary During mitosis, chromatin condensation shapes chromosomes as separate, rigid, and compact sister chromatids to facilitate their segregation. Here, we show that, unlike wild-type yeast chromosomes, non-chromosomal DNA circles and chromosomes l
Publikováno v:
eLife
eLife, Vol 4 (2015)
eLife, 4
eLife, Vol 4 (2015)
eLife, 4
The segregation of eukaryotic chromosomes during mitosis requires their extensive folding into units of manageable size for the mitotic spindle. Here, we report on how phosphorylation at serine 10 of histone H3 (H3 S10) contributes to this process. U
Autor:
Tom Kruitwagen, Nils A. Rall, Yves Barral, Yogesh B. Ostwal, Wolfgang Fischle, Bryan J. Wilkins, Heinz Neumann, Kyoko Hiragami-Hamada, Marco Winkler
Publikováno v:
Science
Chromosome Condensation The forces that shape the structure of the highly condensed metaphase chromosomes seen during cell division in eukaryotes are still largely unknown. In vitro evidence suggests that the amino-terminal tails of the histones—su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255b1ec43d87842c9efb9375a753c66d
https://hdl.handle.net/11858/00-001M-0000-0015-11C4-E11858/00-001M-0000-0015-11C0-511858/00-001M-0000-0015-11C3-0
https://hdl.handle.net/11858/00-001M-0000-0015-11C4-E11858/00-001M-0000-0015-11C0-511858/00-001M-0000-0015-11C3-0
Autor:
Sascha Dehler, Kota Miura, Jean-Karim Hériché, Tom Kruitwagen, Boryana Petrova, Christian H. Haering
Publikováno v:
Molecular and cellular biology. 33(5)
Chromosomes undergo extensive conformational rearrangements in preparation for their segregation during cell divisions. Insights into the molecular mechanisms behind this still poorly understood condensation process require the development of new app