Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tom Kozlek"'
Autor:
Amer M Zeidan, Amir Fathi, Ghayas Issa, Harry Erba, Julie Ahsan Mackey, Daniel Corum, Blake Tomkinson, Tom Kozlek, Mollie Leoni, Eunice Wang
Publikováno v:
HemaSphere, Vol 7, p e56956b1 (2023)
Externí odkaz:
https://doaj.org/article/aeae90bfcff5428fb9b933f79cb199f8
Treatment Patterns of Real-World Patients with TRK Fusion Cancer Treated by US Community Oncologists
Publikováno v:
Targeted Oncology. 17:549-561
Neurotrophic tyrosine receptor kinase (NTRK) gene fusions are present across various tumor types with an estimated overall prevalence of less than 1%. Tropomyosin receptor kinase inhibitors (TRKis) block the constitutively activated tyrosine receptor
Publikováno v:
Targeted Oncology.
Neurotrophic tyrosine receptor kinase (NTRK) gene fusions are oncogenic drivers with an estimated prevalence of less than 1% across all solid tumors. Tropomyosin receptor kinase inhibitors (TRKis) block the constitutively activated tyrosine receptor
Publikováno v:
Molecular Cancer Therapeutics. 20:P022-P022
Introduction: NTRK gene fusions have been observed across age groups in a variety of tumor types and are implicated in approximately 1% of all solid tumor cancers. The FDA approved larotrectinib (2018) and entrectinib (2019) for the treatment of TRK