Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tom Godthelp"'
Autor:
T. M. Vroom, W. J. Fokkens, E. A. W. F. M. Severijnen, Paul G.H. Mulder, E. Rijntjes, Adriaan Holm, Tom Godthelp
Publikováno v:
Clinical & Experimental Allergy. 29:1356-1366
Background The effect of long-term topical nasal corticosteroid therapy on nasal inflammatory cells is unclear. Objectives To investigate the long-term effect of fluticasone propionate aqueous nasal spray (FPANS) on nasal mucosal inflammatory cells a
Publikováno v:
American journal of rhinology, 12(1), 21-26. OceanSide Publications Inc.
American Journal of Rhinology, 12, 21-26. OceanSide Publications Inc.
American Journal of Rhinology, 12, 21-26. OceanSide Publications Inc.
Regular and prophylactic use of topical corticosteroids is a well tolerated and effective treatment for allergic rhinitis. The symptomatology of allergic rhinitis is considered to be the result of the accumulation and activation of infiltrating infla
Publikováno v:
Clinical otolaryngology and allied sciences, 23(1), 69-73. Wiley-Blackwell
Clinical Otolaryngology, 23, 69-73. Wiley-Blackwell Publishing Ltd
Clinical Otolaryngology, 23, 69-73. Wiley-Blackwell Publishing Ltd
In a 1-year, placebo-controlled, double-blind, randomized study the long-term effect of Fluticasone Propionate Aqueous Nasal Spray (FPANS) in 42 patients with a perennial allergic rhinitis was studied with regard to safety and efficacy. Twenty-nine p
Publikováno v:
Allergy, 52, 29-32. Wiley-Blackwell Publishing Ltd
Allergy, 52(36 Suppl), 29-32. Wiley-Blackwell
Allergy, 52(36 Suppl), 29-32. Wiley-Blackwell
Topical corticosteroids have proved to be effective in the treatment of allergic rhinitis. The symptomatology of allergic rhinitis is considered to be the result of the accumulation and activation of inflammatory cells and cytokine release and hence
Publikováno v:
Journal of Allergy and Clinical Immunology, 99, 515-521. Mosby Inc.
Journal of allergy and clinical immunology, 99(4), 515-521. Mosby Inc.
Journal of allergy and clinical immunology, 99(4), 515-521. Mosby Inc.
Background: Until now, it has not been possible to identify specific IgE locally in the airway mucosa. In this study we investigated the possibility of determining specific allergen binding locally in the nasal mucosa. Methods: Nasal mucosal biopsy s
Publikováno v:
Journal of Allergy and Clinical Immunology, 100, 739-747. Mosby Inc.
Journal of allergy and clinical immunology, 100(6 Part 1), 739-747. Mosby Inc.
Journal of allergy and clinical immunology, 100(6 Part 1), 739-747. Mosby Inc.
Topical corticosteroids are the therapy of choice for nonallergic, noninfectious perennial rhinitis (NANIPER). However, the efficacy of steroid therapy in NANIPER is controversial, as is its mode of action. To our surprise, of 300 patients initially
Autor:
Paul G.H. Mulder, E. Rijntes, Errol P. Prens, Adriaan Holm, W. J. Fokkens, Alex KleinJan, Tom Godthelp
Publikováno v:
Clinical & Experimental Allergy, 26, 677-688. Wiley-Blackwell Publishing Ltd
Clinical and experimental allergy, 26(6), 677-688. Wiley-Blackwell
Clinical and experimental allergy, 26(6), 677-688. Wiley-Blackwell
Summary Background The role of antigen presenting cells (APC) in allergic rhinitis is underexposed. Allergen presentation to T lymphocytes is probably an important aspect of the pathophysiological mechanism of allergic rhinitis. Objectives The aim of
Autor:
Errol P. Prens, Alex KleinJan, E. C. M. Hoefsmit, Adriaan Holm, Tom Godthelp, Peter Doornenbal, E. Rijntjes, Paul G.H. Mulder, W. J. Fokkens
Publikováno v:
Journal of Allergy and Clinical Immunology. 97:800-811
Background: Eosinophils are thought to play an important role in the symptomatology and pathophysiology of allergic rhinitis. Most quantitative studies on eosinophils in nasal mucosa have focused on the dynamics of eosinophils in the acute and late p
Publikováno v:
Allergy, 51(9), 614-620. Wiley-Blackwell
Mast cells in the nasal mucosa can be studied by means of monoclonal antibodies (mAb) against tryptase (T+MC) and chymase (C+MC). Fixation with acetone gives more positive cells than does fixation with Carnoy's fluid. In frozen biopsy specimens of al
Publikováno v:
Allergy, 50(23 Suppl), 21-24. Wiley-Blackwell
Mast cell degranulation, and the subsequent recruitment of infiltrating inflammatory cells, such as eosinophils, into the nasal mucosa has long been considered the most important model to explain allergic rhinitis. Several studies show a decrease in