Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Tom Foltynie"'
Autor:
Alejandro Martinez-Carrasco, Raquel Real, Michael Lawton, Hirotaka Iwaki, Manuela M. X. Tan, Lesley Wu, Nigel M. Williams, Camille Carroll, Michele T. M. Hu, Donald G. Grosset, John Hardy, Mina Ryten, Tom Foltynie, Yoav Ben-Shlomo, Maryam Shoai, Huw R. Morris
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract The genetic basis of levodopa-induced-dyskinesia (LiD) is poorly understood, and there have been few well-powered genome-wide studies. We performed a genome-wide survival meta-analyses to study the effect of genetic variation on the developm
Externí odkaz:
https://doaj.org/article/cec4d30a7b3a4bf787d978b96c439ea7
Autor:
André Zacharia, Diego Kaski, Walid Bouthour, Viswas Dayal, Matthieu Bereau, Philipp Mahlknecht, Dejan Georgiev, Julie Péron, Tom Foltynie, Ludvic Zrinzo, Marjan Jahanshahi, John Rothwell, Patricia Limousin
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for Parkinson’s disease (PD). Varying the frequency DBS has differential effects on axial and distal limb functions, suggesting differing modulation of
Externí odkaz:
https://doaj.org/article/6ea3bc85784d45b9a13ea5ba6b5a20c5
Autor:
John Eraifej, Joana Cabral, Henrique M. Fernandes, Joshua Kahan, Shenghong He, Laura Mancini, John Thornton, Mark White, Tarek Yousry, Ludvic Zrinzo, Harith Akram, Patricia Limousin, Tom Foltynie, Tipu Z. Aziz, Gustavo Deco, Morten Kringelbach, Alexander L. Green
Publikováno v:
Network Neuroscience, Vol 7, Iss 2, Pp 478-495 (2023)
AbstractBeyond the established effects of subthalamic nucleus deep brain stimulation (STN-DBS) in reducing motor symptoms in Parkinson’s disease, recent evidence has highlighted the effect on non-motor symptoms. However, the impact of STN-DBS on di
Externí odkaz:
https://doaj.org/article/d227c8202a6641dbac584674101c912f
Autor:
Ashwini Oswal, Chunyan Cao, Chien-Hung Yeh, Wolf-Julian Neumann, James Gratwicke, Harith Akram, Andreas Horn, Dianyou Li, Shikun Zhan, Chao Zhang, Qiang Wang, Ludvic Zrinzo, Tom Foltynie, Patricia Limousin, Rafal Bogacz, Bomin Sun, Masud Husain, Peter Brown, Vladimir Litvak
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
In Parkinson’s disease (PD), beta frequency oscillations are synchronised across the cortico-basal-ganglia circuit. The authors show in human participants that high beta frequencies propagate from the cortex to the basal ganglia via the hyperdirect
Externí odkaz:
https://doaj.org/article/cdfc65b27df649a2be40ee8e183add84
Autor:
Friederike Leimbach, James Gratwicke, Tom Foltynie, Patricia Limousin, Ludvic Zrinzo, Marjan Jahanshahi
Publikováno v:
Clinical Parkinsonism & Related Disorders, Vol 1, Iss , Pp 48-51 (2019)
Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) is a relatively new treatment approach for the axial symptoms of Parkinson's disease (PD) and Progressive Supranuclear Palsy (PSP). The results concerning the clinical benefits are va
Externí odkaz:
https://doaj.org/article/2d03ef41f43c41ffac5dedcdf05ac94c
Autor:
Tolga Esat Özkurt, Harith Akram, Ludvic Zrinzo, Patricia Limousin, Tom Foltynie, Ashwini Oswal, Vladimir Litvak
Publikováno v:
NeuroImage, Vol 223, Iss , Pp 117356- (2020)
This study offers a novel and efficient measure based on a higher order version of autocorrelative signal memory that can identify nonlinearities in a single time series. The suggested method was applied to simultaneously recorded subthalamic nucleus
Externí odkaz:
https://doaj.org/article/234d03d12f4243718cb46c4f407938a8
Autor:
James Gratwicke, Ashwini Oswal, Harith Akram, Marjan Jahanshahi, Marwan Hariz, Ludvic Zrinzo, Tom Foltynie, Vladimir Litvak
Publikováno v:
NeuroImage, Vol 221, Iss , Pp 117184- (2020)
Parkinson's disease dementia (PDD) and dementia with Lewy bodies (DLB) are two related diseases which can be difficult to distinguish. There is no objective biomarker which can reliably differentiate between them. The synergistic combination of elect
Externí odkaz:
https://doaj.org/article/81c6b3270069463abecf3f984452146d
Autor:
Tom Foltynie, Tim Grover
Publikováno v:
EClinicalMedicine, Vol 24, Iss , Pp 100456- (2020)
Externí odkaz:
https://doaj.org/article/abbbb8a688c74682a42cfc15d054c403
Autor:
Weihua Li, Nick P. Lao-Kaim, Andreas-Antonios Roussakis, Antonio Martín-Bastida, Natalie Valle-Guzman, Gesine Paul, Eyal Soreq, Richard E. Daws, Tom Foltynie, Roger A. Barker, Adam Hampshire, Paola Piccini
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss , Pp 102409- (2020)
Background: Resting-state functional magnetic resonance imaging (fMRI) studies have demonstrated that basal ganglia functional connectivity is altered in Parkinson’s disease (PD) as compared to healthy controls. However, such functional connectivit
Externí odkaz:
https://doaj.org/article/cee514e0611341078b47e5c3368e9331
Autor:
Antonella Macerollo, Patricia Limousin, Prasad Korlipara, Tom Foltynie, Mark J. Edwards, James Kilner
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Background and Aims: Pathological high amplitude of beta oscillations is thought as the underlying mechanism of motor symptoms in Parkinson's disease (PD), in particular with regard to bradykinesia. In addition, abnormality in a neurophysiological ph
Externí odkaz:
https://doaj.org/article/29e6399ec2b141a79a8a4bdec53281a4