Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Tom D'Arcy"'
Autor:
John J. O'Leary, Sharon A. O'Toole, Feras Abu Saadeh, Charles d'Adhemar, Lucy Norris, Ream Langhe, Tom D'Arcy, Noreen Gleeson, Margaret Lawson, Orla Sheils, Martina Ring, Anthony Davies, Cara Martin, Lynda McEvoy, Stephen Finn, Michael Gallagher, Lynne Kelly, Alexandros Laios, Richard Flavin, Bashir M. Mohamed
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 1, Pp 2085-2103 (2013)
Platinum resistance is a major cause of treatment failure in ovarian cancer. We previously identified matrix metalloproteinase 9 (MMP-9) as a potential therapeutic target of chemoresistant disease. A2780cis (cisplatin-resistant) and A2780 (cisplatin-
Externí odkaz:
https://doaj.org/article/0d99f081f1714192ac999e0a3c2c6efd
Autor:
Charles J d'Adhemar, Cathy D Spillane, Michael F Gallagher, Mark Bates, Katie M Costello, Jacqui Barry-O'Crowley, Kathryn Haley, Niamh Kernan, Ciara Murphy, Paul C Smyth, Ken O'Byrne, Stephen Pennington, Aoife A Cooke, Brendan Ffrench, Cara M Martin, Dearbhaile O'Donnell, Bryan Hennessy, Britta Stordal, Stephen Finn, Amanda McCann, Noreen Gleeson, Tom D'Arcy, Brian Flood, Luke A J O'Neill, Orla Sheils, Sharon O'Toole, John J O'Leary
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100816 (2014)
The prognosis of epithelial ovarian cancer is poor in part due to the high frequency of chemoresistance. Recent evidence points to the Toll-like receptor-4 (TLR4), and particularly its adaptor protein MyD88, as one potential mediator of this resistan
Externí odkaz:
https://doaj.org/article/208a05f77739491a8afed939f68cee69
Publikováno v:
Angewandte Chemie. 134
Hydroxylative dearomatization reactions of phenols (HPD) offer an efficient way to assemble complex, biologically relevant scaffolds. Despite this, enantioselective hydroxylative phenol dearomatizations for the construction of bicyclo[2.2.2]octenones
Autor:
Seamus McDonald, Yanmei Huang, Feras Abu Saadeh, Waseem Kamran, N. Ibrahim, Elizabeth A. Heron, Lucy A. Norris, Cliona Murphy, Nadine Farah, Rizmee Shireen, Noreen Gleeson, Tom D'Arcy, Megan Power Foley, Sharon O'Toole, C. Thompson, Mark Ward, John J. O'Leary
Publikováno v:
Gynecologic Oncology. 160:514-519
To investigate whether HE4 and CA125 could identify endometrioid adenocarcinoma patients who might most benefit from full staging surgery with lymphadenectomy.Sequential patients with a preoperative banked serum and histology of endometrioid adenocar
Autor:
Tom D'Arcy, Benjamin Buckley
Hydroxylative dearomatization reactions of phenols (HPD) offer an efficient way to assemble complex, biologically relevant scaffolds. Despite this, enantioselective hydroxylative phenol dearomatizations for the construction of bicy-clo[2.2.2]octenone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7f3f50cead12e5928285f2b5ee12e13
https://doi.org/10.26434/chemrxiv-2022-lv85f
https://doi.org/10.26434/chemrxiv-2022-lv85f
Autor:
Damien Traynor, Shiyamala Duraipandian, Ramya Bhatia, Kate Cuschieri, Prerna Tewari, Padraig Kearney, Tom D’Arcy, John J. O’Leary, Cara M. Martin, Fiona M. Lyng
Publikováno v:
Articles
Cancers; Volume 14; Issue 7; Pages: 1836
Cancers; Volume 14; Issue 7; Pages: 1836
The mortality associated with cervical cancer can be reduced if detected at the precancer stage, but current methods are limited in terms of subjectivity, cost and time. Optical spectroscopic methods such as Raman spectroscopy can provide a rapid, la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58bb2389b974d0c8019a63dd872acebd
https://arrow.tudublin.ie/radart/87
https://arrow.tudublin.ie/radart/87
Health-related quality of life in women after colposcopy: results from a longitudinal patient survey
Autor:
Mairead O'Connor, John J. O'Leary, Linda Sharp, Grainne Flannelly, Walter Prendiville, Katie M O'Brien, J McRae, Christine White, Alan Ó Céilleachair, Tom D'Arcy, Cara Martin, Carmel Ruttle, Loretto Pilkington
Background: Information concerning the health-related quality-of-life (HRQoL) consequences of colposcopy is limited, particularly over time. In a longitudinal study, we investigated women’s HRQoL at 4, 8 and 12 months post colposcopy and the factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa9c12731a88b6b0f69aa813e4f8077
https://hdl.handle.net/10468/11244
https://hdl.handle.net/10468/11244
Autor:
Linda Sharp, Catherine Comiskey, Christine White, Sharon O'Toole, Tom D'Arcy, Loretto Pilkington, Stephen Reynolds, Niamh Kernan, Cara Martin, Prakashini Banka, John J. O'Leary, Prerna Tewari, Cliona Murphy
Publikováno v:
Journal of oral pathologymedicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral PathologyREFERENCES. 50(7)
Background Considering the shared aetiology of Human Papillomavirus infections in oropharyngeal and cervical cancers and the possible role for sexual transmission, several key aspects of the relationship between cervical and oral infections merit inv
Autor:
Tom D'Arcy, Christine White, Loretto Pilkington, Helen Keegan, Prerna Tewari, Linda Sharp, Cara Martin, Lynne Kelly, John J. O'Leary, Sharon O’ Toole
Publikováno v:
Diagnostic Cytopathology. 46:987-992
Background The aim of this study was to evaluate the clinical performance of the Cobas 4800 HPV test and the Aptima HPV assay for the detection of CIN2+ disease in women referred to colposcopy with minor cytological abnormalities. Methods ThinPrep li
Autor:
S Rizmee, H O’Connor, M Foley, Noreen Gleeson, Waseem Kamran, N Farah, MA Anglim, John J. O'Leary, C. Thompson, Mark Ward, C Murphy, N. Ibrahim, Sharon O'Toole, F AbuSaadeh, Tom D'Arcy, Lucy A. Norris
Publikováno v:
ePoster.
Introduction/Background Endometrial cancer (EC) is the most common gynaecological malignancy. The mainstay of treatment is surgical resection. Currently, there are no sensitive and specific biomarkers for EC. Human Epididymis protein 4 (HE4) shows pr