Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Tom C.-C. Hu"'
Autor:
Jonas W. Perez, Jill A. Harvilchuck, Tom C.-C. Hu, Brian S. Crow, Jerry D. Thomas, Jeffrey J. Wallery, Jennifer Quiñones-González, Brooke G. Pantazides, Rudolph C. Johnson, Thomas A. Blake
Publikováno v:
Anal Bioanal Chem
Chlorine is a toxic industrial chemical with a history of use as a chemical weapon. Chlorine is also produced, stored, and transported in bulk making it a high-priority pulmonary threat in the USA. Due to the high reactivity of chlorine, few biomarke
Autor:
Tom C.-C. Hu
Publikováno v:
The Protein Journal. 40:464-465
Publikováno v:
Magnetic Resonance in Medicine. 66:1353-1361
Myocardial infarction (MI) is a leading cause of death and disabilities. Inflammatory cells play a vital role in the process of postinfarction remodeling and repair. Inflammatory cell infiltration into the infarct site can be monitored using T-weight
Autor:
Autumn Schumacher, William D. Hill, Yidong Yang, Xingming Shi, Tom C.-C. Hu, Jimei Liu, Yuhui Yang
Publikováno v:
Magnetic Resonance in Medicine. 65:1430-1436
How stem cells promote myocardial repair in myocardial infarction (MI) is not well understood. The purpose of this study was to noninvasively monitor and quantify mesenchymal stem cells (MSC) from bone marrow to MI sites using magnetic resonance imag
Publikováno v:
NMR in Biomedicine. 24:46-53
Manganese ions (Mn(2+) ) enter viable myocardial cells via voltage-gated calcium channels. Because of its shortening of T(1) and its relatively long half-life in cells, Mn(2+) can serve as an intracellular molecular contrast agent to study indirect c
Autor:
Toshio Matsuda, Tom C.-C. Hu, Benjamin J. Waghorn, Nathan Yanasak, Jimei Liu, Autumn Schumacher, Akemichi Baba, Stephanie Jacobs
Publikováno v:
Magnetic Resonance in Medicine. 65:239-249
Prolonged ischemia causes cellular necrosis and myocardial infarction (MI) via intracellular calcium (Ca2+) overload. Manganese-enhanced MRI indirectly assesses Ca2+ influx movement in vivo as manganese (Mn2+) is a Ca2+ analog. To characterize myocar
Publikováno v:
Magnetic Resonance in Medicine. 63:33-40
Micrometer-sized iron oxide particles (MPIO) are a more sensitive MRI contrast agent for tracking cell migration compared to ultrasmall iron oxide particles. This study investigated the temporal relationship between inflammation and tissue remodeling
Autor:
Toshio Matsuda, Nathan Yanasak, Yuhui Yang, Ben Waghorn, Akemichi Baba, Tom C.-C. Hu, Autumn Schumacher
Publikováno v:
NMR in Biomedicine. 22:874-881
The sodium-calcium exchanger (NCX) is one of the transporters contributing to the control of intracellular calcium (Ca(2+)) concentration by normally mediating net Ca(2+) efflux. However, the reverse mode of the NCX can cause intracellular Ca(2+) con
The volume aim to be a comprehensive overview of the drug and biologic development process that is often called “the valley of death” (pre-IND through approval) where high costs of studies and high rates of product failure are part of the drug de
Autor:
Joni Taylor, Timothy F. Christian, Tom C.-C. Hu, Andrew E. Arai, Anthony H. Aletras, Alan P. Koretsky
Publikováno v:
Magnetic Resonance in Medicine. 54:196-200
The ability of MnCl2 to enhance canine myocardium and to delineate ischemic areas is demonstrated. A dose–response curve was measured using T1 weighted images in 11 dogs. MnCl2 (36, 113, 360, and 3600 mol) was infused over a period of 3 min. Signal