Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Tom Burdon"'
Autor:
Emily M. Randall, Paul Sopp, Anna Raper, Inga Dry, Tom Burdon, Jayne C. Hope, Lindsey A. Waddell
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Bovine alveolar macrophages (AMs) defend the lungs against pathogens such as Mycobacterium bovis (M. bovis), the causative agent of bovine tuberculosis. However, little is known about the surface molecules expressed by bovine AMs and whether
Externí odkaz:
https://doaj.org/article/9d805f08c2534f1cb1610ca379492d1e
Autor:
Raphaël Pantier, Megan Brown, Sicheng Han, Katie Paton, Stephen Meek, Thomas Montavon, Nicholas Shukeir, Toni McHugh, David A. Kelly, Tino Hochepied, Claude Libert, Thomas Jenuwein, Tom Burdon, Adrian Bird
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Correlative evidence has suggested that the methyl-CpG-binding protein MeCP2 contributes to the formation of heterochromatin condensates via liquid-liquid phase separation. This interpretation has been reinforced by the observation that hete
Externí odkaz:
https://doaj.org/article/8624fe27fea0477cbeee8d7082173fcb
Autor:
Celina M. Yong, Laura Graham, Tariku J. Beyene, Shirin Sadri, Juliette Hong, Tom Burdon, William F. Fearon, Steven M. Asch, Mintu Turakhia, Paul Heidenreich
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 14 (2023)
Background Cardiovascular procedural treatments were deferred at scale during the COVID‐19 pandemic, with unclear impact on patients presenting with non–ST‐segment–elevation myocardial infarction (NSTEMI). Methods and Results In a retrospecti
Externí odkaz:
https://doaj.org/article/85cd28e769a44d0abe68c559f9e0fde4
Autor:
Stephen Meek, Tom Watson, Lel Eory, Gus McFarlane, Felicity J. Wynne, Stephen McCleary, Laura E. M. Dunn, Emily M. Charlton, Chloe Craig, Barbara Shih, Tim Regan, Ryan Taylor, Linda Sutherland, Anton Gossner, Cosmin Chintoan-Uta, Sarah Fletcher, Philippa M. Beard, Musa A. Hassan, Finn Grey, Jayne C. Hope, Mark P. Stevens, Monika Nowak-Imialek, Heiner Niemann, Pablo J. Ross, Christine Tait-Burkard, Sarah M. Brown, Lucas Lefevre, Gerard Thomson, Barry W. McColl, Alistair B. Lawrence, Alan L. Archibald, Falko Steinbach, Helen R. Crooke, Xuefei Gao, Pentao Liu, Tom Burdon
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Infectious diseases of farmed and wild animals pose a recurrent threat to food security and human health. The macrophage, a key component of the innate immune system, is the first line of defence against many infectious agents and
Externí odkaz:
https://doaj.org/article/cf7ad4f4a1df46abb42ac71785840eab
Autor:
Stephen Meek, Jun Wei, Taeho Oh, Tom Watson, Jaime Olavarrieta, Linda Sutherland, Daniel F. Carlson, Angela Salzano, Tamir Chandra, Anagha Joshi, Tom Burdon
Publikováno v:
Stem Cell Reports, Vol 14, Iss 1, Pp 154-166 (2020)
Summary: Rat embryonic stem cells (rESCs) are capable of contributing to all differentiated tissues, including the germ line in chimeric animals, and represent a unique, authentic alternative to mouse embryonic stem cells for studying stem cell pluri
Externí odkaz:
https://doaj.org/article/73abfeba6940457291fa0e02eb90fc60
Autor:
Stephen Meek, Mia Buehr, Linda Sutherland, Alison Thomson, John J Mullins, Andrew J Smith, Tom Burdon
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14225 (2010)
The rat is the preferred experimental animal in many biological studies. With the recent derivation of authentic rat embryonic stem (ES) cells it is now feasible to apply state-of-the art genetic engineering in this species using homologous recombina
Externí odkaz:
https://doaj.org/article/8c371ef902a24926b1013cf4c7153a9b
Autor:
Raphaël Pantier, Megan Brown, Sicheng Han, Katie Paton, Stephen Meek, Thomas Montavon, Toni McHugh, David A. Kelly, Tino Hochepied, Claude Libert, Thomas Jenuwein, Tom Burdon, Adrian Bird
Correlative evidence has suggested that DNA methylation promotes the formation of transcriptionally silent heterochromatin. Accordingly, the methyl-CpG binding domain protein MeCP2 is often portrayed as a constituent of heterochromatin. This interpre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d69aa2cb100d0541ef4b5596d423395
https://doi.org/10.1101/2023.05.09.539985
https://doi.org/10.1101/2023.05.09.539985
Autor:
Celina Yong, Laura Graham, Tariku J. Beyene, Shirin Sadri, Juliette Hong, Tom Burdon, William F. Fearon, Steven M. Asch, Mintu Turakhia, Paul Heidenreich
BackgroundCardiovascular procedural treatments were deferred at scale during the COVID-19 pandemic, with unclear impact on patients presenting with Non-ST Elevation Myocardial Infarction (NSTEMI).MethodsIn a retrospective cohort study of all patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1585646a63ce38f29b777842e51332b
https://doi.org/10.1101/2023.03.07.23286963
https://doi.org/10.1101/2023.03.07.23286963
Autor:
Richard A Axton, Michael Jackson, Maria Kydonaki, Tom Burdon, Stephen Meek, A. H. Taylor, Alexander Medvinsky, Antonella Fidanza, Stanislav Rybtsov, Lesley M. Forrester
Publikováno v:
Stem Cell Reports
Jackson, M, Fidanza, A, Taylor, H, Rybtsov, S, Axton, R, Kydonaki, M, Meek, S, Burdon, T, Medvinsky, A & Forrester, L M 2021, ' Modulation of Aplnr signaling is required during the development and maintenance of the hematopoietic system ', Stem Cell Reports . https://doi.org/10.1016/j.stemcr.2021.02.003
Jackson, M, Fidanza, A, Taylor, H, Rybtsov, S, Axton, R, Kydonaki, M, Meek, S, Burdon, T, Medvinsky, A & Forrester, L M 2021, ' Modulation of Aplnr signaling is required during the development and maintenance of the hematopoietic system ', Stem Cell Reports . https://doi.org/10.1016/j.stemcr.2021.02.003
Summary Apelin receptor (APLNR/AGTRLl1/APJ) marks a transient cell population during the differentiation of hematopoietic stem and progenitor cells (HSPCs) from pluripotent stem cells, but its function during the production and maintenance of hematop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3326f93dc1bd43c9cbb9090ce37c768a
https://doi.org/10.1016/j.stemcr.2021.02.003
https://doi.org/10.1016/j.stemcr.2021.02.003
Autor:
Jaime Olavarrieta, Stephen Meek, Angela Salzano, Tamir Chandra, Jun Wei, Linda Sutherland, Thomas C Watson, Taeho Oh, Anagha Joshi, Tom Burdon, Daniel F. Carlson
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 14, Iss 1, Pp 154-166 (2020)
Meek, S, Wei, J, Oh, T, Olavarrieta, J, Sutherland, L, Carlson, D F, Salzano, A, Chandra, T, Joshi, A & Burdon, T 2020, ' A stem cell reporter for investigating pluripotency and self-renewal in the rat. ', Stem Cell Reports . https://doi.org/10.1016/j.stemcr.2019.12.001
Stem Cell Reports, Vol 14, Iss 1, Pp 154-166 (2020)
Meek, S, Wei, J, Oh, T, Olavarrieta, J, Sutherland, L, Carlson, D F, Salzano, A, Chandra, T, Joshi, A & Burdon, T 2020, ' A stem cell reporter for investigating pluripotency and self-renewal in the rat. ', Stem Cell Reports . https://doi.org/10.1016/j.stemcr.2019.12.001
Summary Rat embryonic stem cells (rESCs) are capable of contributing to all differentiated tissues, including the germ line in chimeric animals, and represent a unique, authentic alternative to mouse embryonic stem cells for studying stem cell plurip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55334f9a88e35d5468f1fe725aab9f2a
https://doi.org/10.1016/j.stemcr.2019.12.001
https://doi.org/10.1016/j.stemcr.2019.12.001